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个人简介

吴洋,博士,助理教授。2012年本科毕业于浙江大学,2016年获得新加坡国立大学博士学位。博士毕业后分别于新加坡国立大学机械系、美国宾州州立大学工程科学与力学系开展博士后研究工作。2020年1月入职哈尔滨工业大学(深圳)机电工程与自动化学院。深圳市海外高层次人才B类。 多年来主要从事生物3D打印技术研究,形成包括3D仿生医用支架设计、制备和应用在内完整的研究体系。利用各种3D打印技术制备可用于肌腱、软骨、多孔组织、皮肤修复等修复的组织替代物。目前共发表专著章节2篇,论文20余篇,并在多个国际会议上作学术报告。研究成果被美国系统工程协会杂志 (ISE Magazine) 等多个科技媒体报道。担任多个本领域著名期刊审稿人,包括Biofabrication, Acta Biomaterialia等。 教育经历 2012-2016 新加坡国立大学,博士学位 2008-2012 浙江大学,学士学位 研究与工作经历 2020.1至今 哈尔滨工业大学(深圳),助理教授 2017.4-2019.12 美国宾州州立大学,博士后 2016.10-2017.4 新加坡国立大学,博士后 科研项目 2023-2025,国家自然科学基金,青年科学基金项目,主持 2023-2025,广东省自然科学基金,面上项目,主持 2023-2025,深圳市科技创新委员会,重点项目,参与 2020-2023,广东省自然科学基金,区域联合基金-青年基金项目,主持 2020-2022,流体动力与机电系统国家重点实验室,开放基金项目,主持 2020-2022,哈尔滨工业大学(深圳)新教师科研启动项目,主持 2020-2022,深圳市海外高层次人才科研专项经费,主持

研究领域

3D打印技术开发及应用,具体包括: 生物3D打印技术在组织与器官修复方面的生物医学应用 细胞团簇打印技术 (Scaffold-free biopritning) 的开发与应用 术中打印技术 (Intraoperative bioprinting) 的开发与应用

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

专著 Wu Y*, Jerry FYH, Ozbolat IT. 3D Bioprinting in Tissue and Organ Regeneration, Elsevier, 2022.9.10 ISBN: 9780323859059/9780128242919 章节著作 Datta P, Wu Y, Yu Y, Moncal KK, Ozbolat IT*.2021. "A Scaffold Free 3D Bioprinted Cartilage Model for In Vitro Toxicology" in Computer-Aided Tissue Engineering. Springer. Wu Y, Zhang Y, Yu Y, Ozbolat IT*. 2020. "3D Coaxial Bioprinting of Vasculature" in 3D Bioprinting. Springer. Peng W, Datta P, Wu Y, Dey M, Ayan B, Dababneh A, Ozbolat IT*. 2017. "Challenges in bio-fabrication of organoid cultures" in Cell biology and translational medicine, vol 3: stem cells, bio-materials and tissue engineering. Springer. Wu Y*, Han Y. 2017.“3D functional scaffolds for tendon tissue engineering”in Functional three-dimensional tissue engineering scaffolds: Technologies and applications. Elsevier. 期刊文章(*为通讯作者, #为共同一作) Wu Y*, Li M, Su H, Chen H, Zhu Y. Up-to-date progress in bioprinting of bone tissue. International Journal of Bioprinting. 2022. 9(1) (IF=, JCR一区) Wu Y*. Electrohydrodynamic jet 3D printing in biomedical applications. Acta Biomaterialia. 2022. 128, 21-41 (IF=, JCR一区) Wu Y*,Ayan B,Moncal KK, Kang Y, Dhawan A,Koduru S, Ravnic D, Kamal F, Ozbolat IT*. Hybrid bioprinting of zonally stratified human articular cartilage using scaffold‐free tissue strands as building blocks. Advanced Healthcare Materials. 2020. 9(22), 2070081 (IF=7.367, JCR一区) Ayan B#, Wu Y#, Karuppagounder V, Kamal F, Ozbolat IT*. Aspiration-assisted bioprinting of the osteochondral interface. Scientific Reports. 10 (1), 1-12 (IF=3.998, JCR一区) Heo D, Alioglu M, Wu Y, Ozbolat V, Ayan B, Dey M, Kang Y, Ozbolat IT*. 3D Bioprinting of carbohydrazide-modified gelatin into microparticle-supended oxidized alginate for fabrication of complex-shaped tissue constructs. ACS Applied Materials & Interfaces. 2020. 12(18), 20295-20306 (IF=8.456, JCR一区) Wu Y, Ravnic DJ, Ozbolat IT*. Intraoperative bioprinting: repairing tissues and organs in a surgical setting. Trends in Biotechnology. 2020. 38(6), 594-605 (IF=13.747, JCR一区) Leberfinger AN, Dinda S, Wu Y, Koduru SV, Ozbolat V, Ravnic DJ, Ozbolat IT*. Bioprinting functional tissues. Acta Biomaterialia. 2018. 95, 32-49 (IF= 6.638, JCR一区) Wu Y*. Novel technique produces micropores, allowing diffusion of nutrients in biofabricated tissues. Journal of 3D printing in medicine. 2019. 3(2), 67-70 Wali A, Dodda A, Wu Y, Ponnone A, Reddy LK, Ozdemir S, Ozbolat IT, Das S*. Biological physically unclonable function. Communications Physics. 2019. 2 (1), 1-10 Dodda A, Wali A, Wu Y, Ponnone A, Reddy LK, Ozdemir S, Ozbolat IT, Das S*. Biological one-way function for secure key generation. Advanced Theory and Simulations 2 (2), 2019. 1800154 (封面文章). Satpathy A, Datta P, Wu Y, Ayan B, Ozbolat IT*. Developments with 3D Bioprinting for Novel Drug Discovery. Expert Opinion On Drug Discovery. 2018. 13 (12), 1115-1129 (IF=4.421, JCR一区). Wu Y, Hospodiuk M, Peng W, Gudapati H, Neuberger T, Koduru S, Ravnic D, Ozbolat IT*. Porous Tissue Strands: Avascular Building Blocks for Scalable Tissue Fabrication. Biofabrication. 2018. 11,015009 (IF=7.236, JCR一区) Sasmal P, Datta P, Wu Y, Ozbolat IT*. 3D bioprinting for modeling vasculature. Microphysiological Systems. 2018. DOI: 10.21037/mps.2018.10.02 Wu Y, Kennedy P, Bonazza N, Yu Y, Dhawan A, Ozbolat IT. Three-dimensional Bioprinting of Articular Cartilage, a Systematic Review. Cartilage. 2018. DOI: 10.1177/1947603518809410 (IF=2.961, JCR一区). Wu B, Takeshita N, Wu Y, Vijayavenkataraman S, Ho KY, Lu WF, Fuh JYH*. Pluronic F127 blended Polycaprolactone scaffolds via e-jetting for esophageal tissue engineering. Journal of Materials Science: Materials in Medicine. 2018. 29:140 (IF=2.448,JCR二区) Datta P, Barui A, Wu Y, Ozbolat V, Moncal KK, Ozbolat IT*. Essential steps in bioprinting: From pre-to post-bioprinting. Biotechnology advances. 2018. 36(5):1481-1504 (IF=12.831, JCR一区) Wu Y*, Han Y, Wong YS, Fuh JYH. Fiber-based scaffolding techniques for tendon tissue engineering. Journal of tissue engineering and regenerative medicine. 2018. 12(7): 1798-1821 (IF=3.319, JCR二区) Hospodiuk M, Dey M, Ayan B, Sosnoski D, Moncal KK, Wu Y, Ozbolat IT*. Sprouting angiogenesis in engineered pseudo islets. Biofabrication. 2018. 10 (3), 035003 (IF=7.236, JCR一区) Wu Y*, Fuh JYH, Wong YS, Sun J. A Hybrid Electrospinning and Electrospraying 3D Printing for Tissue Engineered Scaffolds. Rapid Prototyping Journal. 2017. 23(6):1011-1019 (IF=2.346,JCR二区) Wu Y*, Wu Bin, Vijayavenkataraman S, Wong YS, Fuh JYH. Crimped fiber with controllable patterns fabricated via electrohydrodynamic jet printing. Materials & Design. 2017. 131:384-393 (IF=5.77, JCR一区) Wu Y, Wong YS, Fuh JYH*. Degradation behaviors of geometric cues and mechanical properties in a 3D scaffold for tendon repair. Journal of Biomedical Materials Research Part A. 2017. 105(4):1138-1149 (IF=3.221,JCR二区) Wu Y, Wang Z, Fuh JYH, Wong YS, Wang W, Thian ES*. Direct E-jet printing of three-dimensional fibrous scaffold for tendon tissue engineering. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 2017. 105(3):616-627 (IF=2.674,JCR二区) Wu Y, Wang Z, Fuh JYH, Wong YS, Wang W, Thian ES*. Mechanically-enhanced three-dimensional scaffold with anisotropic morphology for tendon regeneration. Journal of Materials Science: Materials in Medicine. 2016. 27:115 (封面文章, IF= 2.448,JCR二区) Wu Y, Sriram G, Fawzy AS, Fuh JYH, Rosa V, Cao T, Wong YS*. Fabrication and Evaluation of Electrohydrodynamic Jet 3D Printed Polycaprolactone/Chitosan Cell Carriers using Human Embryonic Stem Cell-derived Fibroblasts. Journal of Biomaterials Applications. 2016. 31(2):181-192 (IF= 2.082,JCR二区) Wu Y*, Azmi DFB, Rosa V, Fawzy AS, Fuh JYH, Wong YS, Lu WF. Fabrication of Dentin-Like Scaffolds through Combined 3D Printing and Bio-Mineralisation. Cogent Engineering. 2016. 3(1), 1222777 Wang H, Vijayavenkataraman S, Wu Y, Shu Z, Sun J, Fuh JYH*. Investigation of process parameters of electrohydrodynamic jetting for 3D printed PCL fibrous scaffolds with complex geometries. International Journal of Bioprinting. 2016. 2(1): 63–71. 会议论文及发表演说 (*为通讯作者) Wu Y, Dhawan A, Ozbolat IT*. Scaffold-free Bioprinting of Zonally-stratified Human Articular Cartilage. 12th Annual Postdoc Research Exhibition of Penn State University. 2019 (墙报展示第一名) Wu Y, Dhawan A, Ozbolat IT*. Biofabrication of Zonally-Stratified Construct for Cartilage Repair. ASME 2018 International Mechanical Engineering Congress & Exposition (IMECE).2018 Wu Y, Dhawan A, Ozbolat IT*. Biofabrication of Scaffold-free Tissue Strands Using Human Adipose-derived Stem Cells for Cartilage Repair. The Penn State Bone and Joint Institute Department of Orthopaedics & Rehabilitation Annual Musculoskeletal Research Symposium. 2018 Wu Y, Fuh JYH*, Wong YS. Crimped Fiber Printing via E-jetting for Tissue Engineering. ASME 2017 Manufacturing Science and Engineering Conference. 2017. doi:10.1115/MSEC2017-2742 Wu B, Wu Y, Lu WF, Fuh JYH*. Polycaprolactone/Pluronic F127 tissue engineering scaffolds via electrohydrodynamic jetting for gastro intestinal repair. Procedia CIRP. 2017. 65: 184-188 Wu Y, Azmi DFB, Rosa V, Fawzy AS, Fuh JYH*, Wong YS, Lu WF. Fabrication of Dentin-Like Scaffolds through Combined 3D Printing and Bio-Mineralisation. International Conference on Innovative Design and Manufacturing (ICIDM). 2016. Sun J, Shu Z, Liu H, Fuh JYH*, Wu Y. Spiral Pattern Scaffold Fabrication Using Electrohydrodynamic Jetting. International Conference on Innovative Design and Manufacturing (ICIDM). 2016. Wu Y, Fuh JYH*, Wong YS, Sun J. Fabrication of 3D Scaffolds via E-jet Printing for Tendon Tissue Repair. ASME 2015 International Manufacturing Science and Engineering Conference. 2015. doi:10.1115/MSEC2015-9367 Wu Y, Fuh JYH*, Wong YS, Sun J. A Hybrid E-spinning and E-spraying Biofabrication for Tendon-to-bone Interface. The 2nd International Materials, Industrial, and Manufacturing Engineering Conference (MIMEC). 2015. Wu Y, Wang Z, Fuh JYH, Wong YS, Wang W, Thian ES*. Three-Dimensional Fibrous Scaffold with Geometric Anisotropy and Enhanced Mechanical Properties for Tendon Tissue Engineering. 8th International Conference on Materials for Advanced Technologies of the Materials Research Society of Singapore (ICMAT). 2015. Chen X, Fawzy AS, Chen WX, Wu Y, Sun J, Fuh JYH*. PCL Scaffold Fabrication for Dentin and Periodontal Healing. The 4th International Conference on Additive Manufacturing and Bio-Manufacturing (ICAM-BM). 2014. Wu Y, Yu X, Fuh JYH*, Wong YS, Sun J. Fabrication of Polycaprolactone Scaffolds Using an E-Jet 3D Printing System. 1st International Conference on Progress in Additive Manufacturing (Pro-AM). 2014. Wu Y, Fawzy AS, Li JL, Sun J, Fuh JYH, Thian ES*. Biofabrication of PCL and PCL/Chitosan Scaffolds via Electrohydrodynamic-Jetting for Dentin and Periodontal Healing. 2013 International Symposium on Nano Science and Technology (ISNST). 2013.

学术兼职

Bio-Design and Manufacturing (BDM),副编辑 (Associate Editor), Springer Nature BMC Biomedical Engineering,编委成员 (Editorial Board Member),Springer Nature 美国机械工程师协会 (ASME) 会员 期刊审稿人,包括Biofabrication, Acta Biomaterialia,Journal of Biomaterials Applications, Journal of Tissue Engineering and Regenerative Medicine, Rapid Prototyping Journal, Macromolecular Bioscience等

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