Callan, Anna - Edith Cowan University - School of Medical and Health Sciences

研究领域

Human Exposure to Environmental Contaminants and Associated Health Effects Exposure of susceptible groups, such as children, to persistent toxic substances and the resulting effects of exposure Assessment of the contribution of dietary exposure to persistent toxic substances to an individual’s total level of exposure. Monitoring the biological effects of persistent toxic substance exposure as determined by the measurement of biomarkers of disease, oxidative damage and DNA modifications I obtained my PhD in Biochemistry/Cell Biology however the focus of my research has changed and I am now involved in a number of projects relating to environmental exposures and their health effects. I have been involved in a number of research projects which include investigating the exposure of pregnant women to a range of environmental contaminants (metals, pesticides, persistent organic compounds and Bisphenol A) and children’s exposure to metals, emerging pollutants and particulate matter. Recently I have been working on a study examining exposure to metals in women aged 50 and above, and the effects o exposure on their bone density and kidney function. My background in biological sciences means that I am keen to explore ways of investigating not just personal exposure to environmental contaminants, but also the health effects of exposure and the biological mechanisms underlying those effects. I am particularly interested in environmental contaminants relating to health outcomes in susceptible population groups such as young children and the elderly. The effect of pre-natal exposure to environmental contaminants on pregnancy and birth outcomes is also an area of considerable interest to me. In addition I am keen to explore the contribution of dietary exposure of metals and pollutants to an individual’s total exposure. Environment exposure Biological effects of exposure to environmental contaminants Contribution of diet to exposure to metals and other contaminants

近期论文

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Callan, A., Devine, A., Qi, L., Ng, J., Hinwood, A., (2015), Investigation of the relationship between low environmental exposure to metals and bone mineral density, bone resorption and renal function. International Journal of Hygiene and Environmental Health, 218(5), 444-451, Muenchen, Germany, DOI: 10.1016/j.ijheh.2015.03.010. Hinwood, A., Stasinska, A., Callan, A., Heyworth, J., Ramalingam, M., Boyce, M., McCafferty, P., Odland, J., (2015), Maternal exposure to alkali, alkali earth, transition and other metals: Concentrations and predictors of exposure. Environmental Pollution, 204(2015), 256-263, Oxford, UK, DOI: 10.1016/j.envpol.2015.04.024. Hinwood, A., Callan, A., Heyworth, J., Rogic, D., De Araujo, J., Crough, R., Mamahit, G., Piro, N., Yates, A., Stevenson, G., Odland, J., (2014), Polychlorinated Biphenyl (PCB) and dioxin concentrations in residential dust of pregnant women. Environmental Science Processes and Impacts, 16(12), 2758-2763 , DOI: 10.1039/c4em00383g. Stasinska, A., Heyworth, J., Reid, A., Callan, A., Odland, JO., Duong, PT., Ho, QV., Hinwood, A., (2014), Polybrominated diphenyl ether (PBDE) concentrations in plasma of pregnant women from Western Australia. Science of the Total Environment, 493(2014), 554-561, DOI: 10.1016/j.scitotenv.2014.06.001. Hinwood, A., Callan, A., Heyworth, J., McCafferty, P., Sly, P., (2014), Children?s personal exposure to PM10 and associated metals in urban, rural and mining activity areas. Chemosphere, 108(2014), 125-133, United Kingdom, DOI: 10.1016/j.chemosphere.2014.02.071. Callan, A., Hinwood, A., Devine, A., (2014), Metals in commonly eaten groceries in Western Australia ? a market basket survey and dietary assessment. Food Additives and Contaminants Part A: Chemistry, Analysis, Control, Exposure and Risk Assessment, 31(12), 1968-1981, United Kingdom, DOI: 10.1080/19440049.2014.973457. Hinwood, A., Callan, A., Ramalingam, M., Boyce, M., Heyworth, J., McCafferty, P., Odland, J., (2013), Cadmium, lead and mercury exposure in non smoking pregnant women. Environmental Research, 126( October 2013), 118-124. Ndilila, W., Callan, A., McGregor, L., Kalin, R., Hinwood, A., (2013), Environmental and toenail metals concentrations in copper mining and non mining communities in Zambia. International Journal of Hygiene and Environmental Health , 217(1), 62-69, DOI: 10.1016/j.ijheh.2013.03.011. Reid, A., Callan, A., Stasinska, A., Heyworth, J., Phi, DT., Odland, J., Hinwood, A., (2013), Maternal Exposure to Organochlorine Pesticides in Western Australia. Science of the Total Environment, 449( 1 April 2013), 208-213, DOI: 10.1016/j.scitotenv.2013.01.067.. Stasinska, A., Reid, A., Hinwood, A., Stevenson, G., Callan, A., Odland, J., Heyworth, J., (2013), Concentrations of polybrominated diphenyl ethers (PBDEs) in residential dust samples from Western Australia. Chemosphere, 91(2), 187-193, United Kingdom, DOI: 10.1016/j.chemosphere.2012.12.044.. Callan, A., Hinwood, A., Ramalingam, M., Boyce, M., Heyworth, J., McCafferty, P., Odland, J., (2013), Maternal Exposure to Metals ? Concentrations and Predictors of Exposure. Environmental Research, 126( October 2013), 111-117, DOI: 10.1016/j.envres.2013.07.004. Callan, A., Hinwood, A., Heffernan, A., Eaglesham, G., Mueller, J., Odland, J., (2012), Urinary bisphenol A concentrations in pregnant women. International Journal of Hygiene and Environmental Health, 216(6), 641-644, DOI: 10.1016/j.ijheh.2012.10.002. Lazenby, V., Hinwood, A., Callan, A., Franklin, P., (2012), Formaldehyde Personal Exposure Measurements and Time Weighted Exposure Estimates in Children. Chemosphere, 88(8), 966-973, United Kingdom, DOI: 10.1016/j.chemosphere.2012.03.029. McQueen, HL., Callan, A., Hinwood, A., (2012), Estimating Maternal and Prenatal Exposure to Glyphosate in the Community Setting. International Journal of Hygiene and Environmental Health, 215(6), 570-576, Germany, DOI: 10.1016/j.ijheh.2011.12.002. McKibbin, C., Mares, A., Piacenti, M., Williams, H., Roboti, P., Puumalainen, M., Callan, A., Lesiak-Mieczkowska, K., Linder, S., Harant, H., High, S., Flitsch, S., Whitehead, R., Swanton, E., (2012), Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response. Biochemical Journal, 442(3), 639-648, DOI: doi:10.1042/BJ20111220. Callan, A., Hinwood, A., (2011), Exposures to lead. Reviews on Environmental Health, 26(1), 13-15, DOI: 10.1515/REVEH.2011.003. Callan, A., Winters, M., Barton, C., Boyce, M., Hinwood, A., (2011), Children's Exposure to Metals: A Community-Initiated Study. Archives of Environmental Contamination and Toxicology, 62(4), 714-722, DOI: 10.1007/s00244-011-9727-2.