Dharmarajan, Arunasalam - Curtin University - School of Biomedical Sciences

研究领域

Apoptosis Cell Signalling Cancer Biology Anagiogenesis Cancer Stem Cells

近期论文

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Goh, J., S. Loo, A. Datta, K. Siveen, W. Yap, W. Cai, E. Shin, C. Wang, J. Kim, M. Chan et al. 2016.“microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer.”Biological Reviews xx. In press. Perumal, V., S. Pohl, K. Keane, F. Arfuso, P. Newsholme, S. A. Fox, and A. M. Dharmarajan. 2016.“Therapeutic approach to target mesothelioma cancer cells using the Wnt antagonist, secreted frizzled-related protein 4: Metabolic state of cancer cells.”Experimental Cell Research 341 (2): 218-224. Carnagarin, R., R. Carlessi, P. Newsholme, A. M. Dharmarajan, and C. Dass. 2016.“Pigment epithelium-derived factor stimulates skeletal muscle glycolytic activity through NADPH oxidase-dependent reactive oxygen species production.”International Journal of Biochemistry and Cell Biology 78: 229-236. Warrier, S., R. Marimuthu, S. Sekhar, G. Bhuvanalakshmi, F. Arfuso, A. Das, R. Bhonde, R. Martins, and A. M. Dharmarajan. 2016.“SFRP-mediated Wnt sequestration as a potential therapeutic target for Alzheimer's disease.”International Journal of Biochemistry and Cell Biology 75: 104-111. Regan, S., P. Knight, J. Yovich, J. Stanger, Y. Leung, F. Arfuso, A. M. Dharmarajan, and G. Almahbobi. 2016.“Dysregulation of granulosal bone morphogenetic protein receptor 1B density is associated with reduced ovarian reserve and the age-related decline in human fertility.”Molecular and Cellular Endocrinology 425: 84-93. Carnagarin, R., A. M. Dharmarajan, and C. Dass. 2016.“PEDF attenuates insulin-dependent molecular pathways of glucose homeostasis in skeletal myocytes.”Molecular and Cellular Endocrinology 422: 115-124. Selvi, R., A. Swaminathan, S. Chatterjee, M. Shanmugam, F. Li, G. Ramakrishnan, K. Siveen, A. Chinnathambi, Z. Emam, S. Alharbi et al. 2016.“Inhibition of p300 Lysine Acetyltransferase activity by Luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model.”Oncotarget xx: xx-xx. Chai, E., M. Shanmugam, F. Arfuso, A. M. Dharmarajan, C. Wang, A. Kumar, R. Samy, L. Lim, L. Wang, B. Goh et al. 2016.“Targeting transcription factor STAT3 for cancer prevention and therapy.”Pharmacology and Therapeutics 162: 86-97. Nayeem, S., F. Arfuso, A. M. Dharmarajan, and J. Keelan. 2016.“Role of Wnt signalling in early pregnancy.”Reproduction, Fertility and Development 28. In press. Perumal, V., K. Krishnan, E. Gratton, A. M. Dharmarajan, and S. A. Fox. 2015.“Number and brightness analysis of sFRP4 domains in live cells demonstrates vesicle association signal of the NLD domain and dynamic intracellular responses to Wnt3a.”International Journal of Biochemistry and Cell Biology 64: 91-96. Carnagarin, R., A. M. Dharmarajan, and C. Dass. 2015.“Molecular aspects of glucose homeostasis in skeletal muscle - A focus on the molecular mechanisms of insulin resistance.”Molecular and Cellular Endocrinology 417: 52-62. Carnagarin, R., A. M. Dharmarajan, and C. Dass. 2015.“PEDF-induced alteration of metabolism leading to insulin resistance.”Molecular and Cellular Endocrinology 401: 98-104. Nayeem, S., A. M. Dharmarajan, and J. Keelan. 2015.“Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model.”Molecular and Cellular Endocrinology 405: 52-62. Bhuvanalakshmi, G., F. Arfuso, M. Millward, A. M. Dharmarajan, and S. Warrier. 2015.“Secreted frizzled-related protein 4 inhibits glioma stem-like cells by reversing epithelial to mesenchymal transition, inducing apoptosis and decreasing cancer stem cell properties.”PLoS One 10 (6). Visweswaran, M., L. Schiefer, F. Arfuso, R. Dilley, P. Newsholme, and A. M. Dharmarajan. 2015.“Wnt antagonist secreted frizzled-related protein 4 upregulates adipogenic differentiation in human adipose tissue-derived mesenchymal stem cells.”PLoS One 10 (2). Regan, S., J. McFarlane, T. O'Shea, N. Andronicos, F. Arfuso, A. M. Dharmarajan, and G. Almahbobi. 2015.“Flow cytometric analysis of FSHR, BMRR1B, LHR and apoptosis in granulosa cells and ovulation rate in merino sheep.”Reproduction 150 (2): 151-163. Pohl, S., R. Scott, F. Arfuso, V. Perumal, and A. M. Dharmarajan. 2015.“Secreted frizzled-related protein 4 and its implications in cancer and apoptosis.”Tumor Biology 36 (1): 143-152. Singh, S., W. Yap, F. Arfuso, S. Kar, C. Wang, W. Cai, A. M. Dharmarajan, G. Sethi, and A. Prem Kumar. 2015.“Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?.”World Journal of Gastroenterology 21 (43): 12261-12273. Surana, R., S. Sikka, W. Cai, E. Shin, S. R. Warrier, H. Tan, F. Arfuso, S. A. Fox, A. M. Dharmarajan, and A. Prem Kumar. 2014.“Secreted frizzled related proteins: Implications in cancers.”Biochimica et Biophysica Acta Reviews on Cancer 1845: 53-65. Warrier, S., G. Bhuvanalakshmi, F. Arfuso, G. Rajan, M. Milward, and A. M. Dharmarajan. 2014.“Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition.”Cancer Gene Therapy 21: 381-388.