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个人简介

教育背景 2001/09-2004/07,西安交通大学,生命科学学院,博士 1998/09-2001/07,第四军医大学,矫形外科学,硕士 1992/09-1995/07,第四军医大学,临床医学,大学专科 工作经历 ➢ 2018/01至今,郑州大学,电气工程学院,教授 ➢ 2008/11-2017/12,郑州大学,电气工程学院,副教授 ➢ 2005/05-2008/11,郑州大学,电气工程学院,讲师 ➢ 1995/07-199/09,解放军第153中心医院,矫形外科 ,住院医师 奖励与荣誉 ➢ 2016年,“基于智能算法的基因多态性判别及生物信息学分析”获得2016年河南省科学技术进步二等奖; ➢ 2014年,“基于B/S结构的口腔三维数字化信息平台”获得2014年河南省科技进步奖三等奖及河南省医学科学技术进步二等奖; ➢ 2013年,“P42.3基因在胃癌细胞中的表达及其蛋白调控网络的分析”获得2013年河南省第二届自然科学学术奖—河南省自然科学优秀学术论文二等奖; ➢ 2011年,2011指导本科毕业设计“智能医用多功能鼻腔护理仪”被评为2011届学校优秀毕业设计(论文)一等奖; ➢ 2010年,2010年获得河南省省级优秀中青年骨干教师。 科研项目 ➢ (主持)河南省自然科学基金面上项目(162300410290),2017/01-2018/12; ➢ (主持)国家重点研发计划重点专项项目子课题(2016YFC1303200),2016/09-2020/12; ➢ (主持)河南省国际科技合作计划(152102410008),2015/02-2016/12; ➢ (主持)国家科技支撑计划子课题,3013BAI02B01,2013/01-2017/12; ➢ (主持)河南省科技合作专项资金,122106000042,2012/10-2014/02; ➢ (参与)国家自然基金面上项目(81470033),2015/01-2016/12; ➢ (参与)河南省开放合作项目,132106000064,2013/02-2017/12; ➢ (参与)国家自然科学基金青年科学基金项目(60905039),2010/01-2013/12; ➢ (参与)中央本级重大增减支项目子课题(2060302),2018.06-2021.12.

研究领域

生物医学工程、生物信息学、智能算法优化

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

[1] Jianhua Zhang,Zheng Zhou,Ning Zhang,Wenwen Jin,Yafeng Ren,Chuanliang Chen,Establishment of preliminary regulatory network of TRPV1 and related cytokines,Saudi Journal of Biological Sciences,2017,24(3):582-588. [2] Guoyong Shan#,Jianhua Zhang#,Qingxia Fan. Analysis of the Relationship Between Molecular Conformation of Single-Chain Variable Fragment and In Vitro Biological Activities by Modeling,Journal of Computational and Theoretical Nanoscience,2014,11(4):1100-1106. [3] Jianhua Zhang,Wang Ma,Zhigang Shang,Rui Xing,Li Shi,Youyong Lu. Analysis of the p42.3 protein structure and regulatory network,Chinese Science Bulletin,2013,58(8):869-872. [4] Jianhua Zhang,Shanhong Liu,Zhigang Shang,Li Shi,Jun Yun . Analysis of the relationship between end-to-end distance and activity of single-chain antibody against colorectal carcinoma,Theoretical Biology and Medical Modelling,2012,9(2):1-11. [5] Jianhua Zhang,Chunlei Lu ,Zhigang Shang,Rui Xing,Li Shi ,Youyong Lu,p42.3 gene expression in gastric cancer cell and its protein regulatory network analysis,Theoretical Biology and Medical Modelling,2012,9(1):1~10 [6] 张建华,张士金. 生物信息学能否推动现代中医药研究的发展? 医学争鸣, 2012,(5):17-20 [7] Jianhua Zhang,Zhigang Shang,Xiaohui Zhang,Yuntao Zhang,Modeling and analysis of Schistosoma Argonaute protein molecular spatial conformation,Asian Pacific Journal of Tropical Biomedicine,2011,1(4):275-278 [8] Jianhua Zhang,Zetao Chen,Analyzing influence on the conformation of single-chain antibody with the differential length of linkers,African Journal of Microbiology Research,2011,5(31):5737-5744. [9] Chunyang Liu,Yanhua Xu, Hong Yang, Jianhua Zhang*. Establishment of axon regeneration regulatory network and the role of low intensity pulsed ultrasound in the network. 2019, 26(8):1922-1926. [10] Yang Yang, Lulu Cheng, LiLi, HongLi, YingyueLi, WenwenJin, ChuanliangChen*, Jianhua Zhang*. Relationship between HIF-1α and apoptosis in rats with traumatic brain injury and the influence of traditional Chinese medicine Sanqi. 2019, 26(8):1995-1999. [11] Junting Liang, Hongjie Gao, Wenwen Jin, Yingyue Li, Menghui Xuan, Shijie Wang, Xiaoqian Sun, Chuanliang Chen*, Jianhua Zhang*. Construction of a mitochondrial-associated protein DRP1 and a lung cancer- associated protein Erbb4 combined regulatory network. 2019, 26(8): 2102-2107. [12] Tongde Tian,Chuanliang Chen,Feng Yang,Jingwen Tang,Junwen Pei,Bian Shi,Ning Zhang,Jianhua Zhang*, Establishment of apoptotic regulatory network for genetic markers of colorectal cancer and optimal selection of traditional Chinese medicine target,Saudi Journal of Biological Sciences,2017,24(3):634-643. [13] Mimi Yin,Pingping Zhang,Hua Liu,Zhuye Gao,Jianhua Zhang*. Protein similarity comparison based on linear neural network and multiple parameters,International Journal of Simulation: Systems, Science & Technology,2016,17(26). [14] 张萍萍,尹咪咪,张建华*. 蛋白质空间结构相似度多参数算法模型的建立郑州大学学报(理学版),2016,48(2):61-66. [15] 尹咪咪,张萍萍,张建华*. 基于BP算法的血液指标联合检测在肝癌及肝炎诊断中的应用,郑州大学学报 (医学版),2016,51(2):190-193. [16] 张萍萍,尹咪咪,张建华*. 血清标记物检测结合智能算法在胃癌诊断中的应用,郑州大学学报 (医学版),2016,51(2):196-200. [17] Dong Chen,JinZhong Liu,Kunyang Li,Guofang Wang,Yu Sun,Jianhua Zhang*,Screening Analysis of the Pathogenic Gene of Dentin Dysplasia Type I Journal of Computational and Theoretical Nanoscience,2014,11(11):1437-1442. [18] Huirong Guo,Yuming Ren,Ning Zhao,Yali Wang,Shuying Li,He Cui,SiJia Zhang,Jianhua Zhang*,Synergistic effect of 5-HT2A receptor gene and MAOA gene on the negative emotion of patients with depression,Clinical Physiology and Functional Imaging,2014,34(4):277-281.

学术兼职

➢  河南省医学工程专业委员会副主任委员

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