Batty, Kevin - Curtin University

研究领域

Antimalarial pharmacology and pharmacokinetics

近期论文

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Page-Sharp, M., T. Nunn, S. Salman, B. Moore, K. T. Batty, T. Davis, and L. Manning. 2016.“Validation and Application of a Dried Blood Spot Ceftriaxone Assay.”Antimicrobial Agents and Chemotherapy 60 (1): 14-23. Knippenberg, B., M. Page-Sharp, S. Salman, B. Clark, J. Dyer, K. T. Batty, T. Davis, and L. Manning. 2016.“Validation and application of a dried blood spot assay for biofilm-active antibiotics commonly used for treatment of prosthetic implant infections.”Antimicrobial Agents and Chemotherapy 60 (8): 4940-4955. Moore, B., J. Benjamin, S. Auyeung, S. Salman, G. Yadi, S. Griffin, M. Page-Sharp, K. T. Batty, P. Siba, I. Mueller et al. 2016.“Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean women.”British Journal of Clinical Pharmacology 82 (1): 199-212. Davis, T., B. Moore, S. Salman, M. Page-Sharp, K. T. Batty, and L. Manning. 2016.“Use of quantitative pharmacology tools to improve malaria treatments.”Expert Review of Clinical Pharmacology Early Online. In press. Moore, B., S. Salman, J. Benjamin, M. Page-Sharp, G. Yadi, K. T. Batty, P. Siba, I. Mueller, and T. Davis. 2015.“Pharmacokinetics of piperaquine transfer into the breast milk of Melanesian mothers.”Antimicrobial Agents and Chemotherapy 59 (7): 4272-4278. Benjamin, J., B. Moore, S. Salman, M. Page-Sharp, S. Tawat, G. Yadi, L. Lorry, P. Siba, K. T. Batty, L. Robinson et al. 2015.“Population pharmacokinetics, tolerability, and safety of dihydroartemisinin-piperaquine and sulfadoxine-pyrimethamine-piperaquine in pregnant and nonpregnant Papua New Guinean women.”Antimicrobial Agents and Chemotherapy 59 (7): 4260-4271. Patel, K., J. Simpson, K. T. Batty, S. Zaloumis, and C. Kirkpatrick. 2015.“Modelling the time course of antimalarial parasite killing: A tour of animal and human models, translation and challenges.”British Journal of Clinical Pharmacology 79 (1): 97-107. Siddalingappa, ., H. A. Benson, D. H. Brown, K. T. Batty, and Y. Chen. 2015.“Stabilization of resveratrol in blood circulation by conjugation to mPEG and mPEG-PLA polymers: Investigation of conjugate linker and polymer composition on stability, metabolism, antioxidant activity and pharmacokinetic profile.”PLoS One 10 (3). Moore, B. R., J. Benjamin, S. Salman, S. Griffin, E. Ginny, M. Page-Sharp, L. J. Robinson, P. Siba, K. T. Batty, I. Mueller et al. 2014.“Effect of Coadministered Fat on the Tolerability, Safety, and Pharmacokinetic Properties of Dihydroartemisinin-Piperaquine in Papua New Guinean Children with Uncomplicated Malaria.”Antimicrobial Agents and Chemotherapy 58: 5784-5794. Senarathna, S. G., and K. T. Batty. 2014.“Interspecies allometric scaling of antimalarial drugs and potential application to pediatric dosing.”Antimicrobial Agents and Chemotherapy 58: 6068-6078. Moore, B. R., S. Salman, J. Benjamin, M. Page-Sharp, L. J. Robinson, E. Waita, K. T. Batty, P. Siba, I. Mueller, T. M. Davis et al. 2014.“Pharmacokinetic Properties of Single-Dose Primaquine in Papua New Guinean Children: Feasibility of Abbreviated High-Dose Regimens for Radical Cure of Vivax Malaria.”Antimicrobial Agents and Chemotherapy 58 (1): 432-439. Ch'ng, J. H., Y. Q. Lee, S. Y. Gun, W. N. Chia, Z. W. Chang, L. K. Wong, K. T. Batty, B. Russell, F. Nosten, L. Renia et al. 2014.“Validation of a chloroquine-induced cell death mechanism for clinical use against malaria.”Cell Death and Disease 5. Patel, K., K. T. Batty, B. R. Moore, P. L. Gibbons, and C. M. Kirkpatrick. 2014.“Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model.”Journal of Antimicrobial Chemotherapy 69: 2155-2163. Patel, K., K. T. Batty, B. R. Moore, P. L. Gibbons, J. B. Bulitta, and C. M. Kirkpatrick. 2013.“Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria.”Antimicrobial Agents and Chemotherapy 57 (1): 508-516. Batty, K. T., S. Salman, B. R. Moore, J. Benjamin, S. Lee, M. Page-Sharp, N. Pitus, K. F. Ilett, I. Mueller, F. W. Hombhanje et al. 2012.“Artemisinin-Naphthoquine Combination Therapy for Uncomplicated Pediatric Malaria: a Pharmacokinetic Study.”Antimicrobial Agents and Chemotherapy 56 (5): 2472-2484. Salman, S., M. Page-Sharp, K. T. Batty, K. Kose, S. Griffin, P. Siba, K. F. Ilett, I. Mueller, and T. M. Davis. 2012.“Pharmacokinetic Comparison of Two Piperaquine-Containing Artemisinin Combination Therapies in Papua New Guinean Children with Uncomplicated Malaria.”Antimicrobial Agents and Chemotherapy 56 (6): 3288-3297. Page-Sharp, M., K. F. Ilett, I. Betuela, T. M. Davis, and K. T. Batty. 2012.“Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay.”Journal of Chromatography B 902: 142-146. Moore, B. R., M. Page-Sharp, J. Stoney, K. F. Ilett, J. D. Jago, and K. T. Batty. 2011.“Pharmacokinetics, Pharmacodynamics and Allometric Scaling of Chloroquine in a Murine Malaria Model.”Antimicrobial Agents and Chemotherapy 55 (8): 3899-3907. Whittell, L. R., K. T. Batty, R. Wong, E. M. Bolitho, S. A. Fox, T. M. Davis, and P. E. Murray. 2011.“Synthesis and antimalarial evaluation of novel isocryptolepine derivatives.”Bioorganic & Medicinal Chemistry 19: 7519-7525. Batty, K. T., B. R. Moore, V. Stirling, K. F. Ilett, M. Page-Sharp, K. B. Shilkin, I. Mueller, S. Rogerson, H. A. Karunajeewa, and T. M. Davis. 2010.“Investigation of reproductive toxicology in piperaquine in mice.”Reproductive Toxicology 29: 206-213.