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Animal Health

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Lorsuwannarat N, Piedrafita D, Chantree P, Sansri V, Songkoomkrong S, Bantuchai S, Sangpairot K, Kueakhai P, Changklungmoa N, Chaichanasak P, Chansela P, Sobhon P. (2014). The in vitro anthelmintic effects of plumbagin on newly excysted and 4-weeks-old juvenile parasites of Fasciola gigantica. Exp Parasitol. 22;136C:5-13. Piedrafita D, Preston S, Kemp J, de Veer M, Sherrard J, Kraska T, Elhay M, Meeusen E. (2013). The Effect of Different Adjuvants on Immune Parameters and Protection following Vaccination of Sheep with a Larval-Specific Antigen of the Gastrointestinal Nematode, Haemonchus contortus. PLoS One. 21;8(10):e78357. McWilliam HE, Piedrafita D, Li Y, Zheng M, He Y, Yu X, McManus DP, Meeusen EN. (2013). Local immune responses of the Chinese water buffalo, Bubalus bubalis, against Schistosoma japonicum larvae: crucial insights for vaccine design. PLoS Negl Trop Dis. 26;7(9):e2460. Hamish McWilliam, H.E.G., Driguez, P., Piedrafita, D., Maupin, K.A., Haab, B.B., McManus, D.P., Meeusen, E.N.T. (2013). The developing schistosome worms elicit distinct immune responses in different tissue regions. Immunology and Cell Biology. 91(7):477-85. Piedrafita D, de Veer MJ, Sherrard J, Kraska T, Elhay M, Meeusen EN. (2012). Field vaccination of sheep with a larval-specific antigen of the gastrointestinal nematode, Haemonchus contortus, confers significant protection against an experimental challenge infection. Vaccine. 30(50):7199-204. Assunta P, Piedrafita D, De Guzman G, Shepherd R, Hamill J, Meeusen E, Walmsley AM. (2012). The effect of plant tissue and vaccine formulation on the oral immunogenicity of a model plant-made antigen in sheep. PLoS One 7(12): e52907. Jayaraj R, Piedrafita D, Spithill T, Smooker P. (2012). Evaluation of the immune responses induced by four targeted DNA vaccines encoding the juvenile liver fluke antigen, cathepsin B in a mouse model. Genet Vaccines Ther. 10(1):7. Lees MS, H Nagaraj S, Piedrafita DM, Kotze AC. (2012), Ingham AB. Molecular cloning and characterisation of ovine dual oxidase 2. Gene. 500(1):40-6. Piedrafita D, Matthews JB.. (2012). A grand scale challenge: vaccine discovery for helminth control in definitive hosts. Parasite Immunol.;34(5):241-2. Young AR, Barcham GJ, McWilliam HE, Piedrafita DM, Meeusen EN. (2012). Galectin secretion and binding to adult Fasciola hepatica during chronic liver fluke infection of sheep. Vet Immunol Immunopathol. 145(1-2):362-7. Hamish E.G. McWilliam, Patrick Driguez, David Piedrafita, Donald P. McManus, and Els N.T. Meeusen. (2011). Novel immunomic technologies for schistosome vaccine development. Parasite Immunology 34(5):276-84. J. Pleasance, E. Wiedosari, H.W. Raadsma, E. Meeusen, Piedrafita, D. (2011). Resistance to liver fluke infection in the natural host is correlated with a type-1 cytokine response. Parasite Immunology 33(9):495-505. M.S. Lees, N.A. Robinson, A.B. Ingham, A.C. Kotze, D.M. Piedrafita. (2011). Dual oxidase 2 and glutathione peroxidase gene expression are elevated in hyperimmunised sheep challenged with Haemonchus contortus. Veterinary Parasitology 179(1-3):113-22. J. Pleasance, H.W. Raadsma, S.E. Estuningsih, E. Meeusen, Piedrafita, D. (2011). Innate and adaptive resistance of Indonesian Thin Tail sheep to liver fluke: A comparative analysis of Fasciola gigantica and F. hepatica infection. Veterinary Parasitology 178(3-4):264-72. Jorge F. Gonzalez, lvaro Hernandez, Jose M. Molina, Antonio Fern??ndez, Herman Raadsma, Els N.T. Meeusen and Piedrafita, D. (2011). Fecundity in adult Haemonchus contortus parasites is correlated with abomasal tissue eosinophils and gamma-delta T cells in resistant Canaria Hair Breed sheep. Veterinary Parasitology 178(3-4):286-92. Robinson N, Pleasance J, Piedrafita D, Meeusen ENT. (2011). The kinetics of local cytokine and galectin expression after challenge infection with the gastrointestinal nematode, Haemonchus contortus. International Journal for Parasitology 41(5):487-93. Piedrafita D, Spithill TW and Raadsma HW (2010). Improving animal and human health through understanding liver fluke immunology. Parasite Immunology 32(8):572-81. Hein WR, Pernthaner A, Piedrafita D and Meeusen ENT. (2010). Immune mechanisms of resistance to gastrointestinal nematode infections in sheep. Parasite Immunology 32(8):541-48. Piedrafita D, Gonzalez J, Raadsma HW & Meeusen ENT (2010). Increased production through parasite control: can ancient breeds of sheep teach us new lessons? Trends in Parasitology 26(12):568-73. Robinson N, Piedrafita D, Snibson K, Harrison P, Meeusen ENT. (2010) Immune cell kinetics in the ovine abomasal mucosa following hyperimmunisation and challenge with Haemonchus contortus. Veterinary Research 41(4):37.

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