Chalker, Justin - Flinders University - Institute for Nanoscale Science and Technology College of Science and Engineering

个人简介

Justin M. Chalker earned a B.S. in Chemistry and a B.A. in the History and Philosophy of Science at The University of Pittsburgh in 2006. At Pittsburgh, he contributed to the total synthesis of several natural products under the direction of Theodore Cohen. Supported by a Rhodes Scholarship and a National Science Foundation Graduate Research Fellowship, Justin then completed his D.Phil. thesis at the University of Oxford under the supervision of Benjamin Davis where he developed several tools for the site-selective modification of proteins, many of which are now commercialised. In 2012, Justin started his independent career as an assistant professor at The University of Tulsa where he established a diverse research program in organic chemistry, biochemistry and material science. In 2015, Justin moved to Flinders University as a Lecturer in Synthetic Chemistry and recipient of an ARC Discovery Early Career Researcher Award. In 2017, Justin was promoted to Senior Lecturer and then to Associate Professor in 2019 and full Professor in 2021. Justin has earned >$6M AUD in competitive funding for his scholarly activities and he has been recognised with several awards for his efforts in teaching and research. These include the South Australian Tall Poppy of the Year (2016), Green Chemistry Emerging Investigator (2017), Dream Chemistry Award Finalist (1 of 5 globally, 2017), the Organic and Biomolecular Chemistry New Talent Award (2018), Eureka Prize Finalist for Outstanding Early Career Research (1 of 3 in Australia, 2018), the SA Science Excellence Awards STEM Educator of the Year (2018), and the AMP Tomorrow Maker fellowship (2018). In 2020, Justin was awarded the Prime Minister’s Prize for New Innovators, one of the top science prizes in Australia.

研究领域

ENVIRONMENT AND SUSTAINABILITY A major research focus for our team is to make renewable materials that benefit the environment and sustainability in the broadest sense. Waste valorisation, pollution capture and sustainable gold mining are three active projects. MATERIAL SCIENCE Our research team is dedicated to developing new methods for the sustainable synthesis of polymers and other functional materials. Metal scavenging polymers, flame resistant composites, and bio-degradable wound dressing are a few materials developed in our laboratory. ORGANIC CHEMISTRY Our efforts in organic chemistry are focused on designing efficient and environmentally benign strategies for preparing valuable molecules. New tactics and catalysts feature prominently in this research. We are also interested in exploring alternative feedstocks for chemical synthesis. CHEMICAL BIOLOGY The biology of post-translational modifications motivates our studies in this area. We are interested in developing chemical probes that can detect specific post-translational modifications in complex biological media. We are also interested in developing new technologies for the synthesis of diagnostic and therapeutic proteins.

近期论文

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Healable carbon fiber composites using an inverse vulcanized polymer matrix Wickramasingha, Y. A.; Stojcevski, F.; Eyckens, D. J.; Hayne, D. J.; Chalker, J. M.; Henderson, L. C. Submitted. Electrochemical synthesis of poly(trisulfides) Pople, J. M. M.; Nicholls, T. P.; Pham, L. N.; Bloch, W. M.; Lisboa, L. S.; Perkins, M. V.; Gibson, C. T.; Coote, M. L.; Jia, Z.; Chalker, J. M. J. Am. Chem. Soc. 2023, 145, 11798-11810 Inverse vulcanized polymers for sustainable metal remediation Müller, F. G.; Lisboa, L. S.; Chalker, J. M. Adv. Susatinable Syst. 2023, 2300010 Nitroxide Radical Surfactants Enable Electrocatalytic Oxidation of Fatty Alcohols in Water Mudugamuwa, C. J.; Xie, Y.; Zhang, K.; Nicholls, T.; Chalker, J. M.; Jia, Z. Green Chem. 2023, 25, 3086-3094 Thermal imaging and clandestine surveillance using low-cost polymers with long-wave infrared transparency Tonkin, S. J.; Pham, L. N.; Gascooke, J. R.; Johnston, M. R.; Coote, M. L.; Gibson, C. T.; Chalker, J. M. Adv. Optical Mater. 2023, in press. DOI:10.1002/adom.202300058 A high value application of reclaimed carbon fibers: environmental remediation and redeployment in structural composites Newman, B.; Doeven, E. H.; Francis, P. S.; Stojcevski, F.; Hayne, D. J.; Chalker, J. M.; Henerdson L. C. Sustain. Mater. Techno. 2023, 35, e00546 Magnetic responsive composites made from a sulfur-rich polymer Lundquist, N. A.; Yin, Y.; Mann, M.; Tonkin, S. J.; Slattery, A. D.; Andersson, G. G.; Gibson, C. T.; Chalker, J. M. Polym. Chem. 2022, 13, 5659-5665 Ionic Effect on Electrochemical Behaviour of Water-Soluble Radical Polyelectrolytes Shi, Y.; Mudugamuwa, C. J.; Abeysinghe, T. N.; Alotaibi, Y. S. M.; Monteiro, M. J.; Chalker, J. M.; Lutkenhaus, J. L.; Jia, Z. Macromolecules, 2022, 55, 5733-5743 Integration of the Exogenous Tuning of Thraustochytrid Fermentation and Sulfur Polymerization of Single-Cell Oil for Developing Plant-like Oils Gupta, A.; Worthington, M. J. H.; Chalker, J. M.; Puri, M. Mar. Drugs 2022, 20, 655. Modelling mercury sorption of a polysulfide coating made from sulfur and limonene Worthington, M. J. H.; Yusrina Muhti, I.; Mann, M.; Jia, Z.; Miller, A. D.; Chalker, J. M. Phys. Chem. Chem. Phys. 2022, 24, 12363-12373 Stretchable and durable inverse vulcanized polymers with chemical and thermal recycling Yan, P.; Zhao, W.; Tonkin, S. J.; Chalker, J. M.; Schiller, T.; Hasell, T. Chem. Mater. 2022, 34, 1167-1178 Reaction of Sulfur and Sustainable Algae Oil for Polymer Synthesis and Enrichment of Saturated Triglycerides Gupta, A.; Worthington, M. J. H.; Patel, H. D.; Johnston, M. R.; Puri, M.; Chalker, J. M. ACS Susatain. Chem. Eng. 2022, 10, 9022-9028 TAAR1: Molecular and clinical insights for the treatment of schizophrenia and related comorbidities Nair, P.; Chalker, J. M.; McKinnon, R.; Langmead, C.; Gregory, K.; Bastiampilai, T. ACS Pharmacol. Transl. Sci. 2022, 5, 183-188 Inverse Vulcanisation of canola oil as a route to recyclable chopped carbon fibre composites Stojcevski, F.; Stanfield, M. K.; Hayne, D.; Mann, M.; Lundquist, N. A.; Chalker, J. M.; Henderson, L. C. Sustain. Mater. Techno. 2022, 32, e00400 Vortex fluidic induced mass transfer across immiscible phases Jellicoe, M.; Igder, A.; Chuah, C.; Jones, D. B.; Luo, X.; Stubbs, K. A.; Crawley, E. M.; Pye, S. .J.; Joseph, N.; Vimalananthan, K.; Gardner, Z.; Harvey, D. P.; Chen, X.; Slaveemini, F.; He, S.; Zhang, W.; Chalker, J. M.; Quinton, J. S.; Tang, Y.; Raston, C. L. Chem. Sci. 2022, 13, 3375-3385 Process for coating surfaces with a copolymer made from sulfur and dicyclopentadiene Mann, M.; Zhang, B. Tonkin, S. J.; Gibson, C. T.; Jia, Z.; Hasell, T.; Chalker, J. M. Polym. Chem. 2022, 13, 1320-1327 Chemically activated S-S metathesis for adhesive-free bonding of polysulfide surfaces Mann, M.; Pauling, P. J.; Tonkin, S. J.; Campbell, J. A.; Chalker, J. M. Macrmol. Chem. Phys. 2021, 2100333 A fairer way to compare researchers at any career stage and in any discipline using open-access citation data Bradshaw, C. J. A.; Chalker, J. M.; Crabtree, S. A.; Eijkelkamp, B. A.; Long, J. A.; Smith, J. R.; Trinajstic, K.; Weisbecker, V. PLoS ONE, 2021, 16, e0257141 Reaction of [18F]fluoride at heteroatoms and metals for imaging of peptides and proteins by positron emission tomography Scroggie, K. R.; Perkins, M. V.; Chalker, J. M. Front. Chem. 2021, 9, 687678 Carbonisation of a polymer made from sulfur and canola oil Mann, M.; Luo, X.; Tikoalu, A. D.; Gibson, C. T.; Yin, Y.; Al-Attabi, R.; Andersson, G. G.; Rason, C. L.; Henderson, L. C.; Pring, A.; Hasell, T.; Chalker, J. M. Chem. Commun. 2021, 57, 6296-6299 Polymers Made by Inverse Vulcanization for Use as Mercury Sorbents Chalker, J. M.; Mann, M.; Worthington, M. J. H.; Esdaile, L. J. Org. Mater. 2021, 3, 362-373 Sub-Micron Moulding Topological Mass Transport Regimes in Angled Vortex Fluidic Flow Alharbi, T. M. D.; Jellicoe, M.; Luo, X.; Vimalanathan, K.; Alsulami, I. K.; Al Harbi, B. S.; Chen, X.; Stubbs, K. A.; Chalker, J. M.; Zhang, W.; Boulos, R. A.; Jones, D. B.; Quinton, J. S.; Raston C. L. Nanoscale Adv. 2021, 3, 3064-3075 Insulating composites made from sulfur, canola oil, and wool Bu Najmah, I.; Lundquist, N. A.; Stanfield, M. K.; Stojcevski, F.; Campbell, J. A.; Esdaile, L. J.; Gibson, C. T.; Lewis, D. A.; Henderson, L. C.; Hasell, T.; Chalker, J. M. Chem SusChem 2021, 14, 2352-2359 Azide-Alkyne Cycloadditions in a Vortex Fluidic Device: Enhanced “On Water” Effects and Catalysis in Flow Oksdath-Mansilla, G.; Kucera, R. L.; Chalker, J. M.; Raston, C. L. Chem. Commun. 2021, 57, 659-662 A critical evaluation of probes for cysteine sulfenic acid Pople, J. M. M.; Chalker, J. M. Curr. Opin. Chem. Biol. 2021, 60, 55-65 Confining a spent lead sorbent in a polymer made by inverse vulcanization prevents leaching Lundquist, N. A.; Chalker, J. M. Sustain. Mater. Techno. 2020, 26, e00222 Chemically induced repair, adhesion, and recycling of polymers made by inverse vulcanization Tonkin, S. J.; Gibson, C. T.; Campbell, J. A.; Lewis, D. A.; Karton, A.; Hasell, T.; Chalker, J. M. Chem. Sci. 2020, 11, 5537-5546 Reactive compression molding post-inverse vulcanization: A method to assemble, recycle, and repurpose sulfur polymers and composites Lundquist, N. A.; Tikoalu, A. D.; Worthington, M. J. H.; Shapter, R.; Tonkin, S. J.; Stojcevski, F.; Mann, M.; Gibson, C. T.; Gascooke, J. R.; Karton, A.; Henderson, L. C.; Esdaile, L. J.; Chalker, J. M. Chem. Eur. J. 2020, 26, 10035-10044 Recent advances in the analysis of per- and polyfluoroalkyl substances (PFAS) - A review Al Amin, M.; Sobhani, Z.; Liu, Y.; Dharmaraja, R.; Chadalavada, S.; Naidu, R.; Chalker, J. M.; Fang, C. Environ. Technol. Inno. 2020, 19, 100879 Vortex Fluidic Ethenolysis, Integrating a Rapid Quench of Ruthenium Olefin Metathesis Catalysts Pye, S. J.; Chalker, J. M.; Raston, C. L. Aust. J. Chem. 2020, 73, 1138-1143 Mercury sorbents made by inverse vulcanization of sustainable triglycerides: the plant oil structure influences the rate of mercury removal from water Tikoalu, A. D.; Lundquist, N. A.; Chalker, J. M. Adv. Sustainable Syst. 2020, 4, 1900111 Proteome-wide survey of cysteine oxidation using a norbornene probe Alcock, L. J.; Langini, M.; Stühler, K.; Remke, M.; Perkins, M. V.; Bernardes, G. J. L.; Chalker, J. M. ChemBioChem, 2020, 21, 1329-1334 Crosslinker co-polymerization for property control in inverse vulcanisation Smith, J. A.; Green, S. J.; Petcher, S.; Parker, D. J.; Zhang, B.; Worthington, M. J. H.; Wu, X.; Kelly, C. A.; Baker, T.; Gibson, C. T.; Campbell, J. A.; Lewis, D. A.; Jenkins, M. J.; Willcock, H.; Chalker, J. M; Hasell, T. Chem. Eur. J. 2019, 25, 10433-10440 Polymer Supported Carbon for Safe and Effective Remediation of PFOA- and PFOS-Contaminated Water Lundquist, N. A.; Sweetman, M. J.; Scroggie, K. R.; Worthington, M. J. H.; Esdaile, L. J.; Alboaiji, S. F. K.; Plush, S. E.; Hayball, J. D.; Chalker, J. M ACS Sustainable Chem. Eng. 2019, 7, 11044-11049 Synthesis and Applications of Polymers Made by Inverse Vulcanization Chalker, J. M.; Worthington, M. J. H.; Lundquist, N. A.; Esdaile, L. J. Top. Curr. Chem. 2019, 377, 16 Norbornene Probes for the Detection of Cysteine Sulfenic Acid in Cells Alcock, L. J.; Oliveira, B. L.; Deery, M. J.; Pukala, T. L.; Perkins, M. V.; Bernardes, G. J. L.; Chalker, J. M. ACS Chem. Biol. 2019, 14, 594-598 Chemoselective and continuous flow hydrogenations in thin films using a palladium nanoparticle catalyst embedded in cellulose paper Phillips, J. M.; Ahamed, M.; Duan, X.; Lamb, R. N.; Qu, X.; Zheng, K.; Zou, J.; Chalker, J. M.; Raston, C.L. ACS Appl. Bio Mater. 2019, 2, 488–494 Sulfur polymer composites as controlled-release fertilisers Mann, M.; Kruger, J. E.; Andari, F.; McErlean, J.; Gascooke, J. R.; Smith, J. A.; Worthington, M. J. H.; McKinley, C. C. C.; Campbell, J. A.; Lewis,D. A.; Hasell, T.; Perkins, M. V.; Chalker, J. M. Org. Biomol. Chem. 2019, 17, 1929-1936 Sustainable Polysulfides for Oil Spill Remediation: Repurposing Industrial Waste for Environmental Benefit Worthington, M. J. H.; Shearer, C. J.; Esdaile, L. J.; Campbell, J. A.; Gibson, C. T.; Legg, S. K.; Yin, Y.; Lundquist, N.A; Gascooke, J. R.; Albuquerque, I. S.; Shapter, J. G.; Andersson, G. G.; Lewis, D. A.; Bernardes, G. J. L.; Chalker, J. M. Adv. Sustainable Syst. 2018, 2, 1800024 A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis Scroggie, K. R.; Alcock, L. J.; Matos, M. J.; Bernardes, G. J. L.; Perkins, M. V.; Chalker, J. M.Peptide Science, 2018, e24069 Chemo and regioselective lysine modification on native proteins Matos, M.; Oliveira, B.; Martínez-Sáez, N.; Guerreiro, A.; Cal, P. M. S. D.; Bertoldo, J.; Maneiro, M.; Perkins, E.; Howard, J.; Deery, M.; Chalker, J. M.; Corzana, F.; Jiménez-Osés, G.; Bernardes, G. J. L. J. Am. Chem. Soc. 2018, 140, 4004-4017 The Mercury Problem in Artisanal and Small-Scale Gold Mining Esdaile, L. J.; Chalker, J. M. Chem. Eur J. 2018, 24, 6905-6916 Norbornene probes for the study of cysteine oxidation Alcock, L. J.; Farrell, K. D.; Akol, M. T.; Jones, G. H.; Tierney, M. M.; Kramer, H. B.; Pukala, T. L.; Bernardes, G. J. L.; Perkins, M. V.; Chalker, J. M. Tetrahedron 2018, 74, 1220-1228 Polysulfides made from re-purposed waste are sustainable materials for removing iron from water Lundquist, N. A.; Worthington, M. J. H.; Adamson, N.; Gibson, C. T.; Johnston, M. R.; Ellis, A. V.; Chalker, J. M. RSC Adv. 2018, 8, 1232-1236 Chemical Methods for Mapping Cysteine Oxidation Alcock, L. J.; Perkins, M.V.; Chalker, J. M. Chem. Soc. Rev. 2018, 47, 231-268 Organic Oxidations Promoted in Vortex Driven Thin Films Under Continuous Flow Pye, S. J.; Dalgarno, S. J.; Chalker, J. M.; Raston, C. L. Green Chem. 2018, 20, 118-124