Miners, John - Flinders University - Department of Clinical Pharmacology

研究领域

Drug and chemical metabolism in humans, particularly sources of variability in drug elimination and its pharmacokinetic and therapeutic consequences. Current interests include: Structure-function relationships and genetic polymorphisms of human UDP-glucuronosyltransferases and cytochromes P450 In vitro (in vitro-in vivo extrapolation) and computational models for the prediction of drug and chemical metabolism parameters in vivo Drug-drug interactions Metabolomics (including biomarkers of drug response) Therapeutic drug monitoring

近期论文

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Tucker, G. and Miners, J. (2011). What's in a name? British Journal of Clinical Pharmacology, 71(5) pp. 785-786. [10.1111/j.1365-2125.2010.03817.x] [Scopus] Polasek, T.M. and Miners, J.O. (2010). Response to "zolpidem pharmacokinetics and pharmacodynamics in metabolic interactions involving CYP3A: Sex as differentiating factor" European Journal of Clinical Pharmacology, 66(9) pp. 957-958. [10.1007/s00228-010-0855-9] [Scopus] Doogue, M.P., Martin, J., Miners, J.O. and Somogyi, A.A. (2009). Prescribing in liver disease. Australian Prescriber, 32(5) pp. 120-120. [Scopus] Polasek, T.M. and Miners, J.O. (2008). Macrolide-theophylline interactions: No role for the inhibition of cytochrome P4501A2. British Journal of Clinical Pharmacology, 66(6) pp. 898-900. [10.1111/j.1365-2125.2008.03299.x] [Scopus] Knights, K.M., Mangoni, A.A. and Miners, J.O. (2007). Authors' reply: Nonselective nonsteroidal anti-inflammatory drugs and increased cardiovascular events: emotional stress could be the explanation. British Journal of Clinical Pharmacology, 63(4) pp. 502-502. [10.1111/j.1365-2125.2006.02788.x] [Scopus] Miners, J.O. and Day, R. (2007). Relationships between the adverse effects of drugs and genetic polymorphism in genes encoding drug metabolizing enzymes. British Journal of Clinical Pharmacology, 63(3) pp. 380-381. [10.1111/j.1365-2125.2006.02737.x] [Scopus]