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研究领域

Innovation technology in biomacromolecular modification and bioprocess design for vaccine development; Development of biodegradable targeted drug/gene delivery system; Vaccine formulation, storage and stability; Investigation of assembly process in peptides, virus like particles (VLP) proteins

近期论文

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Du X., Shi B.Y., Liang J., Bi J.X., Dai S., Qiao S.Z., Developing Functionalized Dendrimer-like Silica Nanoparticles with Hierarchical Pores as Advanced Delivery?Nanocarriers, Advanced Materials, 2013, (accepted). Shi B.Y., Hu Z., Dai S and Bi J.X., Qiao S.Z.(2013), Intracellular Microenvironment Responsive Polymer: A Multiple-stage Transport Platform for High-performance Gene Delivery, Small (accepted) Shi B.Y., Hu Z., Dai S and Bi J.X., (2013); Developing a chitosan supported imidazole Schiff-base for high-efficiency gene delivery, Polymer Chemistry. 4(3):840-850; Shi B.Y., Shen Z.Y., Hu Z., Dai S and Bi J.X., (2012); Exploring N-Imidazolyl-O-Carboxymethyl Chitosan for High Performance Gene Delivery, Biomacromolecules, 13(1): 146-53 ; Shen Z.Y., Shi B.Y., Hu Z., Bi J.X., and Dai S., (2012); Exploring low-positively charged thermosensitive copolymers as gene delivery vectors, Soft Matter, 8(5): 1385-1394, Shi B.Y., Deng L., Xiaolin Shi X.L., Dai S., Hu Z., Bi J.X and Guo M.J., (2012); The enhancement of neural stem cell survival and growth by co-culturing with expanded sertoli cells in vitro, Biotechnology Progress, 28(1): 196?C205; Shen Z.Y, Li Y., Kohama K., Bi, J.X., (2011), Improved drug targeting of cancer cells by utilizing actively targetable folic acid-conjugated albumin nanospheres; Pharmacological Research, 63: 51?C58; Shen Z.Y., Wei W., Hideyuki T., Bi J.X., and Dai S., (2011), A galactosamine-mediated drug delivery carrier for targeted liver cancer therapy, Pharmacological Research, 64(4): 410-419; Zhang H., Dai S., Bi J.X. and Liu K.K, (2011), Biomimetic three-dimensional microenvironment for controlling stem cell fate, Interface Focus, 1(5):792-803; Zhang Y., Luo J., Bi., J.X., Su Z.G.(2010). J. of Chromatography A, 1217: 3668?C3673; Huang Y.D., Bi J.X., Su Z.G., (2010); Protein Expression and Purification 74 257?C263; Shi B-Y, Bi J-X., Guo M-J., Zhang S-L., (2010). Cell Proliferation 43, 275?C286; Lu Y., Wang L., Xue Y., Zhang C., Xing X.H., Lou K., Bi J.X, Su Z.G.(2009); Biochemical Engineering Journal, 43:135-141; Bi, J.X., Huang Y.D., Su Z.G., King K., Middelberg A., (2008), J. of Biotechnol., 136S(1):S645-S646; Wu T.; Huang Y.D.; Bi J.X.; Zhang Y.; Sun L. J.; Sun C.B.; Su Z.G.; (2008); Chinese Journal of Biotechnology, 24(7): 1279-1284; Liu Y.H., Bi J.X., Zeng A.-P., Yuan J.Q. A cybernetic model to describe the dynamics of myeloma cell cultivations, Applied Mathematics and Computation,?2008, 205:84-97; Liu Y.H., Bi J.X., Zeng A.-P.,Yuan J.Q., A simple kinetic model for myeloma cell culture with consideration of lysine limitation, 2008, Bioprocess Biosyst Eng, 2008, 31(6): 569-577. Huang Y.D., Bi J.X., Zhou W.B., Su Z.G., et al. (2007), Protein Expression and Purification, 2007, 56: 301-310; Li Y., Bi, J.X., Y.D.Huang, Su Z.G. et al., (2007); Process Biochemistry, 42,315-319; Zhou W.B., Bi J.X., Li Y., Huang Y.D., Su Z.G., et al.,(2007). Process Biochemistry, 42:751-756;

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