Little, Tanya - University of Adelaide

研究领域

Gastrointestinal factors involved in the regulation of appetite and energy intake Obesity Nutrition Gastrointestinal nutrient sensing

近期论文

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Seimon RV, Brennan IM, Russo A, Little TJ, Jones KL, Standfield S, Wishart JM, Horowitz M, Feinle-Bisset C. Gastric emptying, mouth-to-cecum transit, glycemic, insulin, incretin and energy intake responses to a mixed-nutrient liquid in lean, overweight and obese males. Am J Physiol Endocrinol Metab. Published online before print December 4, 2012, doi: 10.1152/ajpendo.00533.2012. Psichas A, Little TJ, Lal S, McLaughlin JT. Colestyramine slows gastric emptying of liquids and reduces appetite in healthy subjects. Neurogastroenterol Motil 24: 1095-1011, 2012. Jones RB, McKie S, Astbury N, Little TJ, Tivey S, Lassman DJ, McLaughlin JT, Luckman S, Williams SR, Dockray GJ, Thompson DG. Functional neuroimaging demonstrates that ghrelin inhibits the central nervous system response to ingested lipid. Gut 61: 1543-61, 2012. Wu T, Zhao BR, Bound MJ, Checklin HL, Bellon M, Little TJ, Young RL, Jones KL, Horowitz M, Rayner CK. Effects of different sweet preloads on incretin hormone secretion, gastric emptying and postprandial glycemia in healthy humans. Am J Clin Nutr 95: 78-83, 2012. Little TJ, Gopinath AG, Patel E, McGlone A, Lassman DJ, D'Amato M, McLaughlin JT, Thompson DG. Gastric emptying of hexose sugars: role of osmolality, molecular structure and the CCK1 receptor. Neurogastroenterol Motil 22: 1183-1190, 2010. Seimon RV, Lange K, Little TJ, Brennan IM, Pilichiewicz A, Feltrin KL, Smeets A, Horowitz M, Feinle-Bisset C. Pyloric pressures and plasma CCK concentrations are major determinants of acute energy intake in healthy lean males. Am J Clin Nutr 92: 61-68, 2010. Little TJ, Gupta N, Case RM, Thompson DG, McLaughlin JT. Sweetness and bitterness taste of meals per se does not mediate gastric emptying in humans. Am J Physiol Regul Integr Comp Physiol 297: R632-639, 2009. Seimon RV, Wooster T, Otto B, Golding M, Day L, Little TJ, Horowitz M, Clifton PM, Feinle-Bisset C. The droplet size of intraduodenal fat emulsions influences antropyloroduodenal motility, hormone release and appetite in healthy males. Am J Clin Nutr 89: 1729-1736, 2009. Brennan IM, Feltrin KL, Nair NS, Hausken T, Little TJ, Gentilcore D, Wishart JM, Jones KL, Horowitz M, Feinle-Bisset C. Effects of phases of the menstrual cycle on gastric emptying, glycemia, plasma GLP-1 and insulin, and energy intake in healthy lean women. Am J Physiol Gastrointest Liver Physiol 297: G602-610, 2009. Brennan IM, Little TJ, Feltrin KL, Smout A, Wishart J, Horowitz M, Feinle-Bisset C. Dose-dependent effects of cholecystokinin-8 on antropyloroduodenal motility, gastrointestinal hormones, appetite and energy intake in healthy men. Am J Physiol Endocrinol Metab 295: E1487-1494, 2008. Nair NS, Brennan IM, Little TJ, Gentilcore D, Hausken T, Jones KL, Wishart JM, Horowitz M, Feinle-Bisset C. Reproducibility of energy intake, gastric emptying, blood glucose, plasma insulin and cholecystokinin responses in healthy young males. Br J Nutr 101: 1094-1102, 2009. Feltrin KL, Little TJ, Meyer JH, Rades TR, Horowitz M, Feinle-Bisset C. Comparative effects of intraduodenal administration of lauric and oleic acids on antropyloroduodenal motility, plasma cholecystokinin and peptide YY, and energy intake in healthy males. Am J Clin Nutr 87: 1181-1187, 2008. Little TJ, Feltrin KL, Meyer JH, Horowitz M Chapman IM, Feinle-Bisset C. A high-fat diet for 3 weeks raises fasting plasma cholecystokinin (CCK), but does not affect antropyloroduodenal motility, PYY and ghrelin, appetite or energy intake during exogenous CCK-8 infusion in healthy lean men. Am J Physiol Regul Integr Comp Physiol 294: R45-51, 2008. Pilichiewicz AN, Papadopoulos P, Brennan IM, Little TJ, Meyer JH, Wishart J, Horowitz M, Feinle-Bisset C. Load-dependent effects of duodenal lipid on antropyloroduodenal motility, plasma CCK and PYY, and energy intake in healthy men. Am J Physiol Regul Integr Comp Physiol 293: R2170-2178, 2007. Gentilcore D, Little TJ, Feinle-Bisset C, Samsom M, Smout AJPM, Horowitz M, Jones KL. Role of 5-hydroxytryptamine mechanisms in mediating the effects of small intestinal glucose on blood pressure and antropyloroduodenal motility in older subjects. Am J Physiol Gastrointest Liver Physiol 293: G692-G698, 2007. Little TJ, Russo A, Meyer JH, Horowitz M, Smyth D, Tsopelas C, Bellon M, Wishart JM, Jones KL, Feinle-Bisset C. Free fatty acids have more potent effects on gastric emptying, gut hormones and appetite than triacylglycerides. Gastroenterology 133: 1124-1131, 2007. Feltrin KL, Little TJ, Meyer JH, Horowitz M, Rades T, Wishart J, Feinle-Bisset C. Effects of lauric acid on antropyloroduodenal motility, plasma CCK and PYY, appetite and energy intake are dependent on load, but not concentration, in healthy humans. J Physiol 581: 767-777, 2007. Little TJ, Doran S, Meyer JH, Smout AJPM, O'Donovan DG, Wu KL, Jones KL, Wishart J, Rayner CK, Horowitz M, Feinle-Bisset C. The release of GLP-1 and ghrelin, but not GIP and CCK, by glucose is dependent on the length of small intestine exposed. Am J Physiol Endocrinol Metab 291: E647-E655, 2006. Little TJ, Pilichiewicz AN, Russo A, Phillips L, Jones KL, Nauck MA, Wishart J, Horowitz M, Feinle-Bisset C. Effects of intravenous GLP-1 on gastric emptying and intragastric distribution in healthy subjects - relationships with postprandial glycemic and insulinemic responses. J Clin Endocrinol Metab 91: 1916-1923, 2006. Pilichiewicz AN, Little TJ, Brennan IM, Meyer JH, Wishart J, Otto B, Horowitz M, Feinle-Bisset C. Effects of load, and duration, of duodenal lipid on antropyloroduodenal motility, plasma CCK and PYY, and energy intake in healthy men. Am J Physiol Regul Integr Comp Physiol 290: R668-R677, 2006.