Johnson, Ian - University of Adelaide

研究领域

Ian is the head of the Motor Neurone Laboratory. With colleagues, he was the first to describe the response of gamma motoneurones to injury and through collaborations in the London and Munich provided the first descriptions of neurotrophic factor changes in Motor Neurone Disease. He has a longstanding research interest in the role of the peripheral target in motor and sensory neuronal survival and provided the first description of adult motoneuron rescue by transfer of functional copies of the gene for a muscle-derived isoform of IGF-1 called MGF. The current main focus of research is on mechanisms underlying age-related differences in motoneuronal survival, with particular reference to the roles of neurotrophic factors including MGF and neuroinflammation in Motor Neurone Disease. The techinques used include microneurosurgery, confocal and electron microscopy, immunohistochemistry, in-situ hybridisation and cytokine assays using multiplex technology. He is review editor for Frontiers in Neuroscience, Neurology and Psychiatry. Ian is recognised as a teaching expert in anatomy by the University of Adelaide and is a member of the Adelaide Academy which promotes excellence in learning and teaching. He has a research interest in the assessment of the utility of electronic resources in anatomy teaching, with specific reference to whether the resources improve learning outcomes rather than just being well-received in opinion polls. As a member of the Council of the Australian and New Zealand Association of Clinical Anatomists, he is creating a National syllabus for anatomy for medical students. He regularly meets with other anatomists to share best practice as part of the tri-university Adelaide Anatomy Community of Practice.

近期论文

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Johnson, I.P. 2015. Age-related neurodegenerative disease research needs aging models. Frontiers in Aging Neuroscience 7, 168. doi:10.3389/fnagi.2015.00168. Johnson, I.P. & Sears, T.A. (2013). Target-dependence of sensory neurones; An ultrastructural comparison of dorsal root ganglion neurones with allowed or denied reinnervation of peripheral targets. Neuroscience 228: 163-178. Johnson, I.P. Palmer, E., Burton, J., & Brockhouse, M. (2013). Online resources in anatomy: what do students think? Clinical Anatomy 26: 556-563.