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Kumarasiri, M, Teo, THS & Wang, S 2015, 'Dynamical insights of Mnk2 kinase activation by phosphorylation to facilitate inhibitor discovery', Future Medicinal Chemistry. Le, BT, Kumarasiri, M, Adams, J, Yu, M, Milne, RW, Sykes, MJ & Wang, S 2015, 'Targeting Pim kinases for cancer treatment: Opportunities and challenges', Future Medicinal Chemistry, v. 7, no. 1, pp. 35-53. Teo, T, Yang, Y, Yu, M, SK, Gillam, T, Hou, J, Schmid, R, Kumarasiri, M, Diab, S, Albrecht, H, Sykes, M & Wang, S 2015, 'An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis', European Journal of Medicinal Chemistry, v. 103, pp. 539-550. Yu, M, Li, P, KC Basnet, S, Kumarasiri, M, Al Haj Diab, S, Teo, THS, Albrecht, H & Wang, S 2015, 'Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d[pyrimidine derivatives as potent Mnk inhibitors: Synthesis, structure-activity relationship analysis and biological evaluation', European Journal of Medicinal Chemistry, v. 95, pp. 116-126. Al Haj Diab, S, Teo, THS, Kumarasiri, M, Li, P, Yu, M, Lam, FK, KC Basnet, S, Sykes, MJ, Albrecht, H, Milne, RW & Wang, S 2014, 'Discovery of 5-( 2-( Phenylamino) pyrimidin-4-yl) thiazol2( 3H)- one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation', ChemMedChem: chemistry enabling drug discovery, v. 9, no. 5, pp. 962-972. Diab, S, Kumarasiri, M, Yu, M, Teo, T, Proud, C, Milne, R & Wang, S 2014, 'MAP kinase-interacting kinases: emerging targets against cancer', Chemistry and Biology, v. 21, no. 4, pp. 441-452. Fu, H, Valiathan, R, Payne, L, Kumarasiri, M, Mahasenan, K V, Mobashery, S, Huang, P & Fridman, R 2014, 'Glycosylation at Asn211 regulates the activation state of the discoidin domain receptor 1 (DDR1)', Journal of Biological Chemistry, v. 289 no. 13, pp. 9275-9287. O'Daniel, P I, Peng, Z, Pi, H, Testero, SA, Kumarasiri, M & Chang, M 2014, 'Discovery of a new class of non-?-lactam inhibitors of penicillin-binding proteins with gram-positive antibacterial activity', Journal of the American Chemical Society, v. 136, no. 9, pp. 3664-3672. Fu, H, Sohail, A, Valiathan, R, Wasinski, BD, Kumarasiri, M, Mahasenan, K V, Bernardo, MM, Tokmina-Roszyk, D, Fields, GB, Mobashery, S & Fridman, R 2013, 'Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases', Journal of Biological Chemistry, v. 288, no. 17, pp. 12114-12129. Fu, H, Valiathan, R, Arkwright, R, Sohail, A, Mihai, C, Kumarasiri, M, Mahasenan, K V, Mobashery, S, Huang, P, Agarwal, A & Fridman, R 2013, 'Discoidin domain receptors: Unique receptor tyrosine kinases in collagen-mediated signaling', Journal of Biological Chemistry, v. 288 no. 11, pp. 7430-7437. Otero, LH, Rojas-Altuve, A, Llarrull, L I, Carrasco-Lopez, C, Kumarasiri, M, Lastochkin, E, Fishovitz, J, Dawley, M, Hesek, D, Lee, M, Johnson, D, Fisher, J, Chang, M, Mobashery, S & Hermoso, JA 2013, 'How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function', Proceedings of the National Academy of Sciences of USA, v. 10 no. 42, pp. 16808-16813. Smith, DP, Antunes, AP, Stewart, R, Toth, M, Kumarasiri, M, Chang, M, Mobashery, S & Vakulenko, S 2013, 'Structural basis for carbapenemase activity of the OXA-23 ?-Lactamase from acinetobacter baumannii', Chemistry and Biology, v. 20, no. 9, pp. 1107-1115. Smith, DP, Kumarasiri, M, Zhang, W, Hesek, D, Lee, KH, Toth, M, Vakulenko, S, Fisher, J, Mobashery, S & Chen, YT 2013, 'Structural analysis of the role of Pseudomonas aeruginosa penicillin-binding protein 5 in ?-lactam resistance', Antimicrobial Agents and Chemotherapy, v. 57, no. 7, pp. 3137-3146. Kumarasiri, M, Llarrull, L I, Borbulevych, O, Fishovitz, J, Lastochkin, E, Baker, W & Mobashery, S 2012, 'An amino acid position at crossroads of evolution of protein function: Antibiotic sensor domain of BlaR1 protein from Staphylococcus aureus versus class D ?-lactamases', Journal of Biological Chemistry, v. 287, no. 11, pp. 8232-8241. Lee, KH, Ikejiri, M, Klimpel, D, Toth, M, Espahbodi, M, Hesek, D, Forbes, C, Kumarasiri, M, Noller, B, Chang, M & Mobashery, S 2012, 'Structure-activity relationship for thiirane-based gelatinase inhibitors', ACS Medicinal Chemistry Letters, v. 3 no. 6, pp. 490-495. Park, J-K, Lee, KH, Yeo, KJ, Ryu, KS, Kumarasiri, M, Hesek, D, Lee, M, Mobashery, S, Song, J, Kim, I, Lee, J-S, Cheong, M, Jeong, Y-J & Kim, H 2012, 'Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane', The FASEB Journal, v. 26 no. 1, pp. 219-228. Smith, DP, Frase, S, Toth, M, Kumarasiri, M, Wiafe, K, Munoz, J, Mobashery, S & Vakulenko, S 2012, 'Structural basis for progression toward the carbapenemase activity in the GES family of ?-lactamases', Journal of the American Chemical Society, v. 134, no. 48, pp. 19512-19515. Artola-Recolons, C, Carrasco-Lopez, C, Llarrull, L I, Kumarasiri, M, Lastochkin, E, Martinez, A, Meindl, K, Uson, I, Mobashery, S & Hermoso, JA 2011, 'High-resolution crystal structure of MltE, an outer membrane-anchored endolytic peptidoglycan lytic transglycosylase from Escherichia coli', Biochemistry, v. 50 no. 13, pp. 2384-2386. Borbulevych, O, Kumarasiri, M, Wilson, B, Llarrull, L I, Lee, M, Hesek, D, Shi, Y, Peng, Y, Baker, W & Mobashery, S 2011, 'Lysine N-decarboxylation switch and activation of the ?-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus', Journal of Biological Chemistry, v. 286, no. 36, pp. 31466-31472. Kumarasiri, M, Baker, W, Soudackov, A V & Sharoni, G 2009, 'Computational approach for ranking mutant enzymes according to catalytic reaction rates', The Journal of Physical Chemistry B: Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter, v. 113 no. 11, pp. 3579-3583.