个人简介
陈汉春，男，曾在英国和美国学习生物化学与分子生物学理论和技术7年；曾任教育部高等学校生物学教学指导委员会委员、中南大学生命科学学院副院长及生物化学系主任。负责国家自然科学基金资助项目2项，负责教育部资助课题1项，负责中华医学基金资助项目子课题1项，参与“973”项目1项，参与中国-加拿大合作研究课题2项，负责省级、校级教改科研课题26项；获省部级奖2项和校级奖12项；申请国家发明专利3项、授权专利1项；主编和参编教材20部；发表科研论文120篇，克隆并在人类基因库注册完整cDNA序列55条；指导博士后4名、博士生8名、硕士生32名、本科生16名。
研究领域
人类重大疾病发生与治疗的分子机理、环境/基因与疾病、生物转化。
近期论文
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1．Han-chun Chen*, Yan-fei Cao, Wei-xin Hu, Xin-fa Liu, Qing-xia Liu, Ji Zhang and Jia Liu. Genetic polymorphisms of phase Ⅱ metabolic enzymes and lung cancer susceptibility in a population of Central South China. Dis Markers. 2006,22(3):141-152.
2．Han-chun Chen*, Wei-xin Hu, Qing-xia Liu, Wen-kai Li, Fang-zhi Chen, Zhou-zhou Rao, Xin-fa Liu, Ya-ping Luo and Yan-fei Cao. Genetic polymorphisms of metabolic enzymes CYP1A1，CYP2D6，GSTM1 and GSTT1 and leukemia susceptibility. European Journal of Cancer Prevention，2008, 17(3):251-258.
3. LIU Jia, CHEN Han-chun*, RAO Zhou-zhou, WAN Xin-xing, XU Ai-hua, Md. Asaduzzaman Khan, ZHANG Nuo, ZHANG Dian-zheng. Identification of heptapeptides interacting with IFN-α-sensitive CML cells. Expert Opin. Investig. Drugs. 2011, 20(12):1583-1589.
4. Md. Asaduzzaman Khan, Han-chun Chen*, Xin-xing Wan, Mousumi Tania, Ai-hua Xu, Fang-zhi Chen, and Dian-zheng Zhang. Regulatory Effects of Resveratrol on Antioxidant Enzymes: A Mechanism of Growth Inhibition and Apoptosis Induction in Cancer Cells. Mol. Cells. 2013, 35(3):219-225.
5. Xin-xing Wan, Han-chun Chen*, Md. Asaduzzaman Khan, Ai-hua Xu, Fu-lan Yang, Yun-yi Zhang, and Dian-zheng Zhang. ISG15 Inhibits IFN-α Resistant Liver Cancer Cell Growth. BioMed Research International, 2013, Article ID 570909, http://dx.doi.org/10.1155/2013/570909.
6. Mei-juan Zhou, Fang-zhi Chen, Han-chun Chen*. Ubiquitination involved enzymes and Cancer. Med Oncol, 2014, 31:93, DOI 10.1007/s12032-014-0093-6.
7. Xu Yang*, Xiao-peng Tang, Yong-hong Zhang, Kai-zhong Luo, Yong-fang Jiang, Hong-yu Luo, Jian-hua Lei, Wen-long Wang, Ming-ming Li, Han-chun Chen, Shi-lin Deng, Li-ying Lai, Jun Liang, Min Zhang, Yi Tian, and Yun Xu. Prospective Evaluation of the Diagnostic Accuracy of Hepatic Copper Content, as Determined Using the Entire Core of a Liver Biopsy Sample. Hepatology. 2015, 62(6): 1731-1741.
8. Fu-lan Yang, Fang-zhi Chen, Xin-xing Wan, Xi Zhou, Mei-juan Zhou, Han-chun Chen*, Jun-jiang Fu, Dian-zheng Zhang.Effects of a particular heptapeptide on the IFN-α-sensitive CML cells. BioMed Research International. 2015; 2015:325026, doi: 10.1155/2015/325026.
9. Mei-juan Zhou, Fang-zhi Chen, Han-chun Chen*, Xin-xing Wan, Xi Zhou, Qian Fang and Dian-zheng Zhang. ISG15 inhibits cancer cell growth and promotes apoptosis. International Journal of Molecular Medicine. 2017, 39(2): 446-452.
10.Farjana Yeasmin Khusbu, Fang‐Zhi Chen, Han‐Chun Chen*. Targeting ubiquitin specific protease 7 in cancer: A deubiquitinase with great prospects. Cell Biochemistry & Function. 2018; DOI: 10.1002/cbf.3336
学术兼职
湖南省生物化学与分子生物学学会副理事长，湖南省生理科学会常务理事；湖南省浏阳市科技创新专家咨询委员会委员；中南大学本科教学督导委员会医学教育建设组组长；校级开放式精品示范课堂负责人；国家及省、市科研项目和成果评审人
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