个人简介
陈超,中南大学生命科学学院研究员,博士生导师, 硕士生导师, 副院长。国自然优秀青年基金获得者;入选湖南省创新领军人才、湖湘高层次人才聚集工程创新团队。湖南省青年骨干教师培养对象。中国遗传学会青年委员会委员、中华医学会医学遗传学分会生物信息学组副组长、湖南省生物信息学会副理事长、湖南省遗传学会常务理事、湖南省神经科学学会理事等职务。
研究领域
1、基于人脑组织的基因表达调控及在神经精神疾病中的作用,
2、多组学相关的生物信息学研究,
3、人脑类器官模型开发及在神经精神疾病中的应用。
近期论文
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Chaodong Ding, Chunling Zhang, Richard Kopp, Liz Kuney, Qingtuan Meng, Le Wang, Yan Xia, Yi Jiang, Rujia Dai, Shishi Min, Wei-Dong Yao, Ma-Li Wong, Hongyu Ruan*, Chunyu Liu*, Chao Chen*. Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia. Molecular Psychiatry. 26, 3444–3460 (2021)
Qingtuan Meng*, Le Wang, Rujia Dai, Jiawen Wang, Zongyao Ren, Sihan Liu, Yan Xia, Yi Jiang, Fangyuan Duan, Kangli Wang, Chunyu Liu*, Chao Chen*. Integrative analyses prioritize GNL3 as a risk gene for bipolar disorder. Molecular Psychiatry. 25, 2672–2684 (2020)
Yi Jiang, Gina Giase, Kay Grennan, Annie W. Shieh, Yan Xia, Lide Han, Quan Wang, Qiang Wei, Rui Chen, Sihan Liu, Kevin P. White, Chao Chen*, Bingshan Li,*, Chunyu Liu*, DRAMS: A Tool to Detect and Re-Align Mixed-up Samples for Integrative Studies of Multi-omics Data. PLoS Computational Biology, 2020 Apr 13;16(4):e1007522
Yan Xia, Rujia Dai, Kangli Wang, Chuan Jiao, Yuchen Xu, Honglei Li, Xi Jing, Yu Chen, Richard Kopp, Gina Giase, Chunling Zhang, Yi Jiang, Chao Chen*, Chunyu Liu*. Sex-differential DNA methylation and associated regulation networks in human brain implicated in the sex-biased risks of psychiatric disorder. Molecular Psychiatry, 26, 835–848 (2021)
Qingtuan Meng, Kangli Wang, Tonya Brunetti, Yan Xia, Chuan Jiao, Dominic Fitzgerald, Amber Thomas, Lindsey Jay, Heather Eckart, Kay Grennan, Kevin P. White, The PsychENCODE Consortium, Chao Chen*, Chunyu Liu*, The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes. Science Translational Medicine, 2018;10(472):eaat6912. doi:10.1126/scitranslmed.aat6912
Chao Chen*, Qingtuan Meng, Yan Xia, Chaodong Ding, Lijun Cheng, Preethi Gunaratne, Richard A. Gibbs, Shishi Min, Rujia Dai, Le Wang, Cristian Coarfa, Jeffrey G. Reid, Chunling Zhang, Chuan Jiao, Yi Jiang, Gina Giase, Amber Thomas, Dominic Fitzgerald, Tonya Brunetti, Annie Shieh, Cuihua Xia, Yongjun Wang, Yunpeng Wang, Judith A. Badner, Elliot S. Gershon, Kevin P White, Chunyu Liu*. The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Science Translational Medicine, 10(472):eaat8178 (2018).
Le Wang, Yan Xia, Yu Chen, Rujia Dai, Wenying Qiu, Chao Chen*. Brain Banks Spur New Frontiers in Neuropsychiatric Research and Strategies for Analysis and Validation. Genomics, Proteomics & Bioinformatics, August 2019 17(4): 402-414
Chuan Jiao, Lingling Huang, Rujia Dai, Yu Wei, Cuihua Xia, Jiacheng Dai, Yan Xia, Shunan Zhao, Liu Yi, Qingtuan Meng, Kangli Wang, Chunyu Liu*, Chao Chen*. BrainEXP: a database featuring with spatiotemporal expression variations and co-expression organizations in human brains. Bioinformatics, 2019 Jan 1;35(1):172-174.