个人简介
周勇,男,生理学系副主任。
长期从事肺损伤修复的细胞与分子机制研究,致力于探讨急性肺损伤和肺纤维化时肺内花生四烯酸代谢紊乱和糖代谢重编程的病理生理学意义,以及有效治疗策略的开发。
主持国家自然科学基金1项,湖南省级科研项目2项,并参与多项国家自然科学基金等项目研究;授权计算机软件著作权1项,实用新型专利1项。参编医学教材4部。先后2次指导本科生获“全国大学生基础医学创新研究暨实验设计论坛一等奖”(2018年和2020年),积累指导大学生获国家级创新创业项目9项,指导本科生为一作发表SCI论文2篇。
截止当前,共发表SCI收录论文29篇,其中第一作者或通讯作者论文15篇,单篇影响因子最高为8.579;总引用数341次,单篇最高引用为43次;H指数为12。
教育经历
[1] 2003.9-2008.6
中南大学 | 医学检验学 | 学士学位 | 大学本科毕业
[2] 2008.9-2010.6
中南大学 | 生理学 | 硕士学位 | 硕士研究生毕业
硕士研究生二年级时转博
[3] 2010.9-2013.6
中南大学 | 生理学 | 博士学位 | 博士研究生毕业
工作经历
[1] 2018.10-至今
中南大学基础医学院 | 生理学系 | 副教授
[2] 2013.8-2018.9
中南大学基础医学院 | 生理学系 | 讲师
科研项目
[1]脂质分子EETs调控成纤维细胞激活减轻肺纤维化的研究,在研,周勇
[2]EETs靶向调控MMPs/TIMPs减轻/逆转小鼠肺纤维化,在研,湖南省自然科学基金,周勇
[3]EETs调控NLRP3炎症小体活化对内毒素急性肺损伤的保护作用,已结题,国家基金委,周勇
教学成果
[1]2019年基础医学院“三十佳”教学竞赛一等奖,2019-12-20
[2]湖南省生理科学会2017年度学术年会微课比赛
著作成果
[1]生理学[教材].周勇,中南大学出版社,2020
[2]医学机能学实验教程[教材].周勇,科学出版社,2020
获奖信息
[1]第十四届张锡鈞基金全国青年优秀生理学学术论文交流及评奖会,周勇
专利成果
[1]一种用于分子生物实验的转移槽
研究领域
[1] 花生四烯酸代谢及其活性分子EETs在肺内生物活性的研究。
[2] 肺纤维化的发病机制及治疗策略开发。
[3] 急性肺损伤/急性呼吸窘迫综合征的发病机理研究,以及肺损伤修复的分子机制研究。
一、肺纤维化
二、急性肺损伤
三、ARA-CYP-EETs-sEH在肺脏疾病中的作用研究
四、糖代谢重编辑在肺内炎症中的作用研究
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
[1]Li Zi-Ming,Xu Sheng-Ya,Feng Yi-Zhuo,Cheng Yu-Rui,Xiong Jian-Bing.The role of NOX4 in pulmonary diseases.[J].美国:Journal of Cellular Physiology,2020
[2]Luo Xiao-Qin,Duan Jia-Xi,Yang Hui-Hui,Zhang Chen-Yu,Sun Chen-Chen,Guan Xin-Xin,Xiong Jian-Bing,Zu Cheng,Tao Jia-Hao.Epoxyeicosatrienoic acids inhibit the activation of NLRP3 inflammasome in murine macrophages.[J].USA:Journal of Cellular Physiology,2020
[3]Hui-Hui Yang#, Jia-Xi Duan#, Shao-Kun Liu, Jian-Bing Xiong,... Yong Zhou*, Cha-Xiang Guan*.A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation.[J]:Theranostics,2020,10(11):4749-4761
[4]Yan-Feng Zhang#, Chen-Chen Sun#, Jia-Xi Duan, Hui-Hui Yang, ...Yong Zhou*, Cha-Xiang Guan.A COX-2/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress.[J]:Biomedicine & Pharmacotherapy,2020,126:109907
[5]Yong Zhou, Chen-Yu Zhang, Jia-Xi Duan, Qing Li, Hui-Hui Yang, Chen-Chen Sun, ...Shao-Kun Liu*.Vasoactive intestinal peptide suppresses the NLRP3 inflammasome activation in lipopolysaccharide-induced acute lung injury mice and macrophages.[J]:Biomedicine & Pharmacotherapy,2020,121:109596
[6]Chen-Yu Zhang#, Jia-Xi Duan#, Hui-Hui Yang, Chen-Chen Sun,... Yong Zhou*, Cha-Xiang Guan*.COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.[J]:FEBS Journal,2020,287(8):1666-1680
[7]Ming-Yuan Du#, Jia-Xi Duan#, Chen-Yu Zhang, Hui-Hui Yang … Yu-Rui Cheng, Yong Zhou*, Cha-Xiang Guan*.Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.[J]:Cell Biology International,2020,44(1):98-107
[8]Min Shao, Zhi-Bin Wen, Hui-Hui Yang, Chen-Yu Zhang, Jian-Bing Xiong ... Yong Zhou*, Cha-Xiang Guan*.Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells.[J]:Biomedicine & Pharmacotherapy,2019,117:109193
[9]Yan-Feng Zhang, Jun Zhang, Chen-Chen Sun, Chun-Yan Tang... Yong Zhou*, Cha-Xiang Gaun*.Vasoactive intestinal peptide inhibits the activation of murine fibroblasts and expression of interleukin 17 receptor C.[J]:Cell Biology International,2019,43(7):770-780
[10]Wen-Jing Zhong#, Hui-Hui Yang#, Xin-Xin Guan, Jian-Bing Xiong, ... Yong Zhou*, Cha-Xiang Guan*.Inhibition of glycolysis alleviates lipopolysaccharide-induced acute lung injury in a mouse model.[J]:Journal of Cellular Physiology,2019,234(4):4641-4654
[11]Guo-Ying Sun, Hui-Hui Yang, Xin-Xin Guan, Wen-Jing Zhong, ..., Yong Zhou*, Cha-Xiang Guan*.Vasoactive intestinal peptide overexpression mediated by lentivirus attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation.[J]:Molecular Immunology,2018,97:8-15
[12]Yong Zhou, Ping Li, Jia-Xi Duan, ..., Dong-Sheng Ouyang, Cha-Xiang Guan*.Aucubin Alleviates Bleomycin-Induced Pulmonary Fibrosis in a Mouse Model.[J]:Inflammation,2017,40(6):2062-2073
[13]Yong Zhou, Tian Liu, Jia-Xi Duan, ..., Bruce D. Hammock, Jian-Xin Jiang*, Cha-Xiang Guan*.Soluble epoxide hydrolase inhibitor attenuates lipopolysaccharide-induced acute lung injury and improves survival in mice.[J]:Shock,2017,47(5):638-645
[14]Yong Zhou, Guo-Ying Sun, ... Bruce D. Hammock, Xiang Fang, Jian-Xin Jiang*, Cha-Xiang Guan*.Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice.[J]:Cell and tissue research,2016,363(2):399-409
[15]Yong Zhou, Min Zhang, Guo-Ying Sun, Yong-Ping Liu, Wen-Zhuo Ran, Li Peng, Cha-Xiang Guan.Calcitonin gene-related peptide promotes the wound healing of human bronchial epithelial cells via PKC and MAPK pathways.[J]:Regul Pept,2013,184(6):22-29
学术兼职
[1] 2019.11-2023.11
湖南省生理科学会第十二届理事会理事(NO. 2019L096)