个人简介
韩兰芝,女,1976年6月生,山东郓城县人,博士,现为中国农业科学院植物保护研究所研究员,硕士生导师。
1999年获青岛农业大学植物保护专业学士学位,2004年获南京农业大学农业昆虫与害虫防治专业博士学位,2007年6月中国农业科学院植物保护研究所生物安全专业博士后流动站出站并留所工作至今。2012年11月-2013年12月在美国田纳西大学昆虫学专业进行访学合作研究。
先后主持国家自然科学基金项目两项(30800723和31572336),主持转基因生物新品种培育重大专项重点课题(2009ZX08011-007B)1项和子课题“RNAi转基因植物环境安全评价技术(2018ZX0801101B)”1项。作为主要科研骨干参加转基因生物新品种培育重大专项课题1项(2016ZX08011001)、参加农业部财政专项-农产品质量安全项目1项。以第一/通讯作者在Applied Environmental and Microbiology、Current Opinion in Insect Science、Pest Management Science、Journal of Invertebrate Pathology等国际期刊和国内核心期刊共发表学术论文50余篇,以第一作者获得授权的国家发明专利4项,参编著作3部。
研究领域
长期从事转基因抗虫作物靶标害虫的抗性演化及抗性治理研究,在转基因抗虫作物的抗性效率评价、靶标害虫对Bt作物的抗性风险评价、抗性演化机制及抗性治理方面均积累了丰富的工作经验。
近期论文
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Zhang C, Luo J, Chen G, Han LZ*, Peng YF. 2019. A new method to obtain isofemale lines for monitoring Chilo suppressalis resistance to Bt toxin. Journal of Invertebrate Pathology, 2019, 163, 8-10.
Du LX, Chen G, Han LZ*, Peng YF. Cadherin CsCad plays differential functional roles in Cry1Ab and Cry1C intoxication in Chilo suppressalis. Scientific Report, 2019, 9: 8507.
Zhou YC, Jia BT, Han LZ*, Peng YF. 2019. A morphological and functional characterization of isolated stem cells from the midgut of Chilo suppressalis larvae. Journal of Asia-Pacific Entomology, 22(3): 982-989.
Tang H, Chen G, Chen FJ, Han LZ*, Peng YF. Development and relative fitness of Cry1C resistance in Chilo suppressalis. Pest Manage Science, 2018, 74:590-597.
Wang XY, Du LX, Liu CX, Gong L, Han LZ*, Peng YF. RNAi in the striped stem borer, Chilo suppressalis, establishes a functional role for aminopeptidase N in Cry1Ab intoxication. Journal of Invertebrate Pathology, 2017, 143: 1-10.
Han LZ*, Jiang XF, Peng YF. Potential resistance management for the sustainable use of insect-resistant genetically modified corn and rice in China. Current Opinion in Insect Science. 2016, 15:139-143.
Li B, Xu YY, Han C, Han LZ*, Hou ML, Peng YF. Chilo suppressalis and Sesamia inferens display different susceptibility responses to Cry1A insecticidal proteins. Pest Management Science, 2015, 71: 1433-1440.
Liu YD, Han LZ, Hou ML. Loss of Genetic variation in laboratory colonies of Chilo suppressalis (Lepidoptera: Crambidae) revealed by mitochondrial and microsatellite DNA markers. Environal Entomology, 2015, 44(1): 73-80.
Gong L, Wang HD, Qi JW, Han LZ, Hu MY, Jurat-Fuentes. 2015. Homologs to Cry toxin receptor genes in a de novo transcriptome and their altered expression in resistant Spodoptera litura larvae. Journal of Invertebrate Pathology, 129, 1-6.
Han LZ*, Han C, Jurat-Fuentes JL, Hou ML, Peng YF. Binding site concentration explains the differential susceptibility of Chilo suppressalis and Sesamia inferens to cry1A-producing rice. Applied and Environmental Microbiology, 2014, 80 (16): 5134-5140.
Wang YN, Ke KQ, Li YH, Han LZ, Liu YM, Hua HX, Peng YF, 2014. Comparison of three transgenic Bt rice lines for insecticidal protein expression and resistance against a target pest, Chilo suppressalis (Lepidoptera: Crambidae). Insect Science, 11(1):78-87
Wang YN, Zhang L, Li YH, Han LZ, Liu YM, Zhu Z, Wang F, Peng YF, 2014. Expression of Cry1Ab protein in a marker-free transgenic Bt rice line and its efficacy in controlling a target pest, Chilo suppressalis (Lepidoptera: Crambidae). Environmental Entomology, 43(2): 528-536.
Li YH, Hu L, Romeis J, Wang YN, Han LZ, Chen XP, Peng YF. 2014. Use of an artificial diet system to study the toxicity of gut-active insecticidal compounds on larvae of the green lacewing Chrysoperla sinica. Biological Control, 69: 45-51.
Han LZ, Li SB, Peng YF. and Hou ML. New artificial diet for continuous rearing of Chilo suppressalis. Annals of the Entomological Society of America, 2012, 105(2): 253-258.