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个人简介

招生专业 0710Z2-计算生物学 086000-生物与医药 招生方向 皮肤基因组学 表型组学 教育背景 2003-09--2009-02 伦敦大学 博士 2002-09--2003-09 杜勒姆大学 硕士 1998-09--2002-06 复旦大学 学士 工作简历 2012-10~现在, 中国科学院上海生命科学研究院, 研究员 2009-02~2012-05,哈佛大学, 博士后研究员 2009-02~2012-05,美国博德研究所, 兼职研究助理 2003-09~2009-02,伦敦大学, 博士 2002-09~2003-09,杜勒姆大学, 硕士 1998-09~2002-06,复旦大学, 学士 科研项目 ( 1 ) EDA通路基因影响东亚人群形态特征的微进化机制研究, 主持, 国家级, 2014-01--2016-12 ( 2 ) 东亚人群的适应性进化, 主持, 国家级, 2014-01--2016-12 ( 3 ) 国家中央组织部“****”计划, 主持, 国家级, 2014-01--2016-12 ( 4 ) 亚欧人群色素相关表型的进化与多基因作用机制, 主持, 国家级, 2017-01--2019-12 ( 5 ) 家犬表型组的量化研究及整合解析, 主持, 部委级, 2017-01--2019-06 ( 6 ) 表型组数据库的构建和遗传分析研究 16JC1400504 2016/7/1 2019/6/30 240, 主持, 省级, 2016-07--2019-06 ( 7 ) 国际人类表型组计划(一期)-人类表型组数据的有效挖掘及分析方法构建, 主持, 省级, 2017-01--2021-12 ( 8 ) 多维生命组学数据智能整合分析, 主持, 国家级, 2018-07--2020-12

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(1) Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans, PLoS Genet, 2018, 通讯作者 (2) Genome-wide variants of Eurasian facial shape differentiation and a prospective model of DNA based face prediction, J Genet Genomics, 2018, 通讯作者 (3) Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment, Am J Hum Genet, 2017, 通讯作者 (4) Indoor PM2.5 exposure affects skin aging manifestation in a Chinese population, Sci Rep, 2017, 通讯作者 (5) Genetic history of Xinjiang's Uyghurs suggests Bronze Age multiple-way contacts in Eurasia, Genetic history of Xinjiang's Uyghurs suggests Bronze Age multiple-way contacts in Eurasia, 2017, 通讯作者 (6) Genetic variants associated with skin aging in the Chinese Han population, J Dermatol Sci, 2017, 通讯作者 (7) A genome-wide association study of basal transepidermal water loss finds variants at 9q34.3 to be associated with skin barrier function, J Invest Dermatol, 2017, 通讯作者 (8) Ancestry variation and footprints of natural selection along the genome in Latin American populations, Scientific reports, 2016, 通讯作者 (9) EDARV370A associated facial characteristics in Uyghur population revealing further pleiotropic effects, Human genetics, 2016, 通讯作者 (10) Traffic-Related Air Pollution Contributes to Development of Facial Lentigines: Further Epidemiological Evidence from Caucasians and Asians, J Invest Dermatol, 2016, 通讯作者 (11) Genome-wide scans reveal variants at EDAR predominantly affecting hair straightness in Han Chinese and Uyghur populations, Hum Genet, 2016, 通讯作者 (12) Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait, J Genet Genomics, 2016, 通讯作者 (13) Epidemiological evidence that indoor air pollution from cooking with solid fuels accelerates skin aging in Chinese women, Journal of dermatological science, 2015, 通讯作者 (14) Characteristics of dental morphology in the Xinjiang Uyghurs and correlation with the EDARV370A variant, Science China Life Sciences, 2014, 通讯作者 (15) The adaptive variant EDARV370A is associated with straight hair in East Asians, Human Genetics, 2013, 通讯作者 (16) Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant, Cell, 2013, 第 1 作者 (17) Exploring population admixture dynamics via empirical and simulated genome-wide distribution of ancestral chromosomal segments, American journal human genetics, 2012, 第 2 作者 (18) Genetic divergence disclosing a rapid prehistorical dispersion of Native Americans in Central and South America, PloS one, 2012, 第 2 作者 (19) X-chromosomal genetic diversity and linkage disequilibrium patterns in Amerindians and non-Amerindian populations, American jounal of human biology, 2011, 第 1 作者

学术兼职

2017-06-01-今,第七届上海人类学学会, 副会长 2016-01-01-今,Ann Hum Genet, 副主编

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