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个人简介

2017-至 今:中国科学院上海营养与健康研究所,研究员 2012-2016:中国科学院上海生命科学研究院营养科学研究所,研究员 2007-2012:美国国立卫生研究院癌症研究所,博士后 2001-2007:美国康奈尔大学营养系,博士 2001-2007:美国康奈尔大学统计系,硕士 1998-2001:北京大学营养与食品卫生系,硕士

研究领域

营养分子流行病,以人群研究(流行病学)为基础,结合表观遗传学组学和基因组学等研究方法,系统的探索表观遗传和遗传因素,以及它们与营养等环境因素的相互作用,对生命全程的健康的影响。目前我们主要研究脂肪酸摄入和代谢在代谢紊乱、癌症和 生长发育中的作用。我们也感兴趣与寻找可以和营养因素共同影响疾病危险性的表观遗传因素。我们也计划通过人群干预研究来进一步评价营养因素的疾病预防和治疗潜力。 1. 脂肪酸与癌症、代谢紊乱和生长发育的关系 2. 遗传和表观遗传在癌症病因学中的意义 3. 人群干预研究

近期论文

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Peiqin Li, Boer Shan, Keyu Jia, Fan Hu, Ying Xiao, Jusheng Zhen, Yu-Tang Gao, Huaying Wang, Ying Gao*. Plasma Omega-3 Polyunsaturated Fatty Acids and recurrence of endometrial cancer. BMC Cancer 2020 Jun;20(1):576 Xin Xu, Huigang Shi, Xiaowen Gong, Pu Chen, Ying Gao, Xinzheng Zhang, Song Xiang. Structural insights into sodium transport by the oxaloacetate decarboxylase sodium pump. eLife 2020 May;9:e53853 Xiaoyang Wang, Jianbo Tian, Qianyu Zhao, Nan Yang, Pingting Ying, Xiating Peng, Danyi Zou, Ying Zhu, Rong Zhong, Ying Gao, Jiang Chang, Xiaoping Miao. Functional characterization of a low-frequency V1937I variant in FASN associated with susceptibility to esophageal squamous cell carcinoma. Arch Toxicol 2020 Jun;94(6):2039-2046 李吉, 方圆, 肖千一, 高莹, 徐望红. DNA甲基化在女性出生体重与成年期肥胖风险关联中的中介效应. 中华流行病学杂志 2019;40(5):590-595 Shuchun Lin, Yun Liu, Lynn R Goldin, Chen Lyu, Xiangyin Kong, Yan Zhang, Neil E Caporaso, Song Xiang, Ying Gao*. Sex related DNA methylation differences in B cell chronic lymphocytic leukemia. Biol Sex Differ 2019 Jan 7;10(1):2 Kangning Chen, Qianyu Zhao, Xiaofan Li, Jing Zhao, Peiqin Li, Shuchun Lin, Hongwei Wang, Jiajie Zang, Ying Xiao, Wanghong Xu, Fuxue Chen, Ying Gao*. Dietary fiber intake and endometrial cancer risk: A systematic review and meta-analysis. Nutrients 2018 Jul 22;10(7):945 Jing Zhao, Xiaofan Li, Xiang Li, Qianqian Chu, Yunhua Zhou, Zi Li, Hong Zhang, Thomas J Brenna, Yiqing Song, Ying Gao*. Associations of plasma very-long-chain SFA and the metabolic syndrome in adults. Br J Nutr 2018 Oct;120(8):855-862 Jie Liu, ShengQuan Mi, Li Du, Xiang Li, Jing Zhao, Hong Zhang, WenHua Zhao*, Ying Gao*. The associations between plasma phytoestrogens concentration and metabolic syndrome risks in Chinese population. PLoS One 2018 Mar 20;13(3):e0194639 Peiqin Li, Jing Zhao, Kumar Kothapalli, Xiang Li, Hui Li, Yuxuan Han, Shengquan Mi, Wenhua Zhao, Qizhai Li, Hong Zhang, Yiqing Song, J. Thomas Brenna, Ying Gao*. A regulatory insertion-deletion polymorphism in the FADS gene cluster influences PUFA and lipid profiles among Chinese adults: a population-based study. Am J Clin Nutr 2018 Jun 1;107(6):867-875 Xiang Li, Hui Li, Jing Zhao, Qi Dai, Chaoran Huang, Langping Jin, Fan Yang, Fuxue Chen, Ouchen Wang, Ying Gao*. Plasma ω-3 and ω-6 fatty acids in thyroid diseases. Oncol Lett 2018 Oct;16(4):5433-5440 Xiaofan Li, Jing Zhao, Peiqin Li, Ying Gao*. Dairy products intake and endometrial cancer risk: a meta-analysis of observational studies. Nutrients 2017 Dec 28;10(1):25 Hui Li, Xiang Li, Jie Liu, Langping Jin, Fang Yang, Junbo Wang, Ouchen Wang, Ying Gao*. Correlation between serum lead and thyroid diseases: papillary thyroid carcinoma, nodular goiter, and thyroid adenoma. Int J Environ Health Res 2017 Oct;27(5):409-419 李慧, 郭倩颖, 柳鹏, 张岩春, 戴智勇, 高莹, 王军波. 不同时期母乳中脂肪酸水平的变化. 中国食物与营养 2017;23(5):54-58 Yanhui Hao, Jing Zhao, Kan Wang, Nannan Feng, Pin Sun, Renjie Chen, Bin Han, Zhipeng Bai, Yiliang Zhu, Ying Gao*, Zhao-lin Xia*. The Association between Particulate Matter Air Pollution and Respiratory Health in Elderly with Type 2 Diabetes Mellitus. J Occup Environ Med 2017 Sep;59(9):830-834 Li Du, Yulong Wang, Hang Zhang, Hong Zhang, Ying Gao*. Folate intake and the risk of endometrial cancer: A meta-analysis. Oncotarget 2016 Dec 20;7(51):85176-85184 Jing Zhao, Lvy Chen, Jian Gao, Li Du, Boer Shan, Hong Zhang, Huaying Wang, Ying Gao*. Dietary fat intake and endometrial cancer risk: a dose-response meta-analysis. Medicine (Baltimore) 2016 Jul;95(27):e4121 Jie Liu, Feixiang Yuan, Jian Gao, Boer Shan, Yulan Ren, Huaying Wang, Ying Gao*. Oral isoflavone supplementation on endometrial thickness: a meta-analysis of randomized placebo-controlled trials. Oncotarget 2016 Apr 5;7(14):17369-17379 Jun Han, Yi Jiang, Xiao Liu, Qingyang Meng, Qiulei Xi, Qiulin Zhuang, Yusong Han, Ying Gao, Qiurong Ding, Guohao Wu. Dietary Fat Intake and Risk of Gastric Cancer: A Meta-Analysis of Observational Studies. PLoS One 2015 Sep 24;10(9):e0138580 Sigurdur Y. Kristinsson#, Ying Gao#, Magnus Bj?rkholm, Sigrun Helga Lund, Jan Sj?berg, Neil Caporaso, Lynn R Goldin, Ola Landgren. Hodgkin lymphoma risk following infectious and chronic inflammatory diseases: a large population-based case-control study from Sweden. Int J Hematol 2015 Jun;101(6):563-568 (# equal contribution) Jing Zhao, Jing Wang, Jinfeng Du, Hongli Xu, Wei Zhang, Quan-Xing Ni, Herbert Yu, Harvey A. Risch, Yu-Tang Gao, Ying Gao*. Urinary prostaglandin E2 metabolite and pancreatic cancer risk: case-control study in urban Shanghai. PLoS One 2015 Feb 13;10(2):e0118004 Wen-Qing Li 1, Nan Hu, Paula L Hyland, Ying Gao, Zhao-Ming Wang, Kai Yu, Hua Su, Chao-Yu Wang, Le-Min Wang, Stephen J Chanock, Laurie Burdett, Ti Ding, You-Lin Qiao, Jin-Hu Fan, Yuan Wang, Yi Xu, Jian-Xin Shi, Fangyi Gu, William Wheeler, Xiao-Qin Xiong, Carol Giffen, Margaret A Tucker, Sanford M Dawsey, Neal D Freedman, Christian C Abnet, Alisa M Goldstein, Philip R Taylor. Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population. Carcinogenesis 2013 Jul;34(7):1536-1542 Ying Gao*, Keith Killian, Hong Zhang, Kai Yu, Qi-Zhai Li, Stephanie Weinstein, Jarmo Virtamo, Margaret Tucker, Philip Taylor, Demetrius Albanes, Paul Meltzer, Neil Caporas. Leukocyte DNA methylation and colorectal cancer among male smokers. World J Gastrointest Oncol 2012 Aug 15;4(8):193-201 David E Capo-Ramos, Ying Gao, Jay H Lubin, David P Check, Lynn R Goldin, Angela C Pesatori, Dario Consonni, Pier Alberto Bertazzi, Andrew J Saxon, Andrew W Bergen, Neil E Caporaso, Maria Teresa Landi. Mood disorders and risk of lung cancer in the EAGLE Case-control study and in the U.S. Veterans Affairs inpatient cohort. Plos One 2012;7(8):e42945 Qizhai Li, Dongdong Pan, Weihua Yue, Ying Gao, Kai Yu. Evaluating rare variants under two- stage design. J Hum Genet 2012 Jun;57(6):352-357 Yoon Jung Park, Herry Herman, Ying Gao, Anders M Lindroth, Benjamin Y Hu, Patrick J Murphy, James R Putnam, Paul D Soloway. Sequences sufficient for programming imprinted germ line DNA methylation defined. PLoS One 2012;7(3):e33024 Ying Gao*, Hormuzd Katki, Barry Graubard, Michael Pollak, Michael Martin, Yuzhen Tao, Robert E Schoen, Timothy Church, Richard B Hayes, Mark H Greene, Sonja I Berndt. Serum IGF1, IGF2, and IGFBP3 and risk of advanced colorectal adenoma. Int J Cancer 2012 Jul 15;131(2):E105-E113 Gao Y*, Baccarelli A, Shu XO, Ji BT, Yu K, Tarantini L, Yang G, Li HL, Hou L, Rothman N, Zheng W, Gao YT, Chow WH. Blood leukocyte Alu and LINE-1 methylation and gastric cancer risk in the Shanghai Women’s Health Study. Br J Cancer 2012 Jan 31;106(3):585-591 Freddy Sitas, Sam Egger, Margaret I Urban, Philip R Taylor, Christian C Abnet, Paolo Boffetta, Dianne L O'Connell, David C Whiteman, Paul Brennan, Reza Malekzadeh, Michael Pawlita, Sanford M Dawsey, Tim Waterboer, on behalf of the InterSCOPE Collaboration. Penelope M Webb, Adèle C Green, Nicholas K Hayward, David Zaridze, Ivana Holcatova, Dana Mates, Neonila Szeszenia-Dabrowska, Gilles Ferro, Vladimir Janout, Maria Paula Curado, Ana Maria Menezes, Sergio Koifman, Farhad Islami, Dariush Nasrollahzadeh, Nan Hu, Alisa M Goldstein, Ying Gao, Ti Ding, Farin Kamangar. InterSCOPE Study: Associations Between Esophageal Squamous Cell Carcinoma and Human Papillomavirus Serological Markers. J Natl Cancer Inst 2012 Jan 18;104(2):147-158 Ying Gao*, Nan Hu, Xiao You Han, Ti Ding, Carol Giffen, Alisa M Goldstein, Philip R Taylor. Risk factors for esophageal and gastric cancers in Shanxi Province, China: a case-control study. Cancer Epidemiol 2011 Dec;35(6):e91-e99 Ying Gao*, Richard B. Hayes, Wen-Yi Huang, Neil E. Caporaso, Laurie Burdette, Meredith Yeager, Stephen J. Chanock, Sonja I. Berndt DNA repair gene polymorphisms and tobacco smoking in the risk for colorectal adenomas. Carcinogenesis 2011;32:882-887

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