Xian, Cory - University of South Australia - School of Pharmacy and Medical Sciences

研究领域

(1) Bone growth mechanisms and regulation; (2) Mechanisms for injury responses and bone growth defects after growth plate fracture; (3) Development of biological treatments (growth factors or stem cells based) for repairing injured growth plate cartilage and for enhancing bone fracture healing; (4) Mechanisms for chemotherapy-induced bone growth arrest and osteoporosis and development of preventative treatments; (5) Improvement of bone health using natural bioactive compounds and nutraceuticals.

近期论文

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Cai, Z, Li, Z, Wang, L, Hsu, H, Xiao, Z & Xian, CJ 2016, 'A three-dimensional finite element modelling of human chest injury following front or side impact loading', Journal of Vibroengineering, v. 18, no. 1, pp. 539?550. Cui, H, Li, T, Wang, L, Su, Y & Xian, C 2016, 'Dioscorea bulbifera polysaccharide and cyclophosphamide combination enhances anti-cervical cancer effect and attenuates immunosuppression and oxidative stress in mice', Scientific Reports, v. 5, Article number 19185 , pp. 1-9. Shi, C-j, Wen, X-s, Gao, H-f, Liu, Z-h, Xu, X-k, Li, L-f, Shen, T & Xian, CJ 2016, 'Steamed root of Rehmannia glutinosa Libosch (Plantaginaceae) alleviates methotrexate-induced intestinal mucositis in rats', Journal of Ethnopharmacology, v. 183, pp. 143-150. Su, Y-W, Chung, R, Ruan, C-S, Chim, SM, Kuek, V, Dwivedi, PP, Hassanshahi, M, Chen, K-M, Xie, Y, Chen, L, Foster, BK, Rosen, V, Zhou, X-F, Xu, J & Xian, CJ 2016, 'Neurotrophin-3 Induces BMP-2 and VEGF Activities and Promotes the Bony Repair of Injured Growth Plate Cartilage and Bone in Rats', Journal of Bone and Mineral Research, v. online, pp. 1-17. Zhou, J, Ma, X-N, Gao, Y-h, Yan, J-L, Shi, W-G, Xian, CJ & Chen, K-M 2016, 'Sinusoidal electromagnetic fields promote bone formation and inhibit bone resorption in rat femoral tissues in vitro', Electromagnetic Biology and Medicine, v. 35, no. 1, pp. 75-83. Chim, S, Kuek, V, Chow, S, Lim, B, Tickner, J, Chung, RSY, Zhao, J, Su, Y, Zhang, G, Xian, CJ, Erber, W, Rosen, V & Xu, J 2015, 'EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades', Journal of Cellular Physiology. Cui, H, Yang, M, Wang, L & Xian, C 2015, 'Identification of a new marine bacterial strain SD8 and optimization of Its culture conditions for producing alkaline protease', PLoS One, v. 10, no. 12, article no. e0146067, pp. 1-13. Fan, C-m, Georgiou, K, McKinnon, R, Keefe, D, Howe, P & Xian, C 2015, 'Combination chemotherapy with cyclophosphamide, epirubicin and 5-fluorouracil causes trabecular bone loss, bone marrow cell depletion and marrow adiposity in female rats', Journal of Bone and Mineral Metabolism, v. 34, no. 3, pp. 277-290. Gao, H, Wen, X & Xian, C 2015, 'Hydroxymethyl furfural in Chinese herbal medicines: Its formation, presence, metabolism, bioactivities and implications', African Journal of Traditional, Complementary and Alternative Medicines. King, TJ, Shandala, T, Lee, A, Foster, B, Chen, K, Howe, P & Xian, C 2015, 'Potential effects of phytoestrogen genistein in modulating acute methotrexate chemotherapy-induced osteoclastogenesis and bone damage in rats', International Journal of Molecular Sciences, v. 16, no. 8, pp. 18293-18311. Wang, L, Dong, J & Xian, CJ 2015, 'Strain Amplification Analysis of an Osteocyte under Static and Cyclic Loading: A Finite Element Study', BioMed Research International, v. 2015, article no. 376474, pp. 1-14. Yan, J-L, Zhou, J, Ma, H, Ma, X-N, Gao, Y-h, Shi, W, Fang, Q, Ren, Q, Xian, CJ & Chen, K-M 2015, 'Pulsed electromagnetic fields promote osteoblast mineralization and maturation needing the existence of primary cilia', Molecular and Cellular Endocrinology, v. 404, pp. 132-140. Zhang, L, Ge, S, Liu, H, Wang, Q, Wang, L & Xian, CJ 2015, 'Contact damage failure analyses of fretting wear behavior of the metal stem titanium alloy-bone cement interface', Journal of The Mechanical Behavior of Biomedical Materials, v. 51, pp. 132-146. Zhong, Y, Wang, L, Dong, J, Zhang, Y, Luo, P, Qi, J, Liu, X & Xian, CJ 2015, 'Three-dimensional Reconstruction of Peripheral Nerve Internal Fascicular Groups', Scientific Reports, v. 5, pp. 1-13. Zhou, FH-h, Yu, Y, Zhou, X-F & Xian, CJ 2015, 'Methotrexate chemotherapy triggers touch-evoked pain and increased CGRP-positive sensory fibres in the tibial periosteum of young rats', Bone, v. 73, pp. 24-31. Zhou, J, Chen, K-M, Zhi, D-J, Xie, Q-J, Xian, CJ & Li, H-Y 2015, 'Effects of pyrite bioleaching solution of Acidithiobacillus ferrooxidans on viability, differentiation and mineralization potentials of rat osteoblasts', Archives of Pharmacal Research. Chung, RSY & Xian, CJ 2014, 'Mechanisms for growth plate injury repair and potential cell-based therapies for generation', Journal of Molecular Endocrinology. Chung, RSY & Xian, CJ 2014, 'Recent Research on the Growth Plate Mechanisms for growth plate injury repair and potential cell-based therapies for regeneration', Journal of Molecular Endocrinology. Chung, RSY, Foster, B & Xian, CJ 2014, 'The potential role of VEGF-induced vascularisation in the bony repair of injured growth plate cartilage', Journal of Endocrinology, v. 221, no. 1, pp. 63-75. Fan, C, Tran, C, Garcia, M, Scherer, M & Xian, CJ 2014, 'Potential roles of metallothioneins I and II in protecting bone growth following acute methotrexate chemotherapy', Journal of Chemotherapy, v. 26, no. 1, pp. 37-48.