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Bala, V, Rao, S, Li, P, Wang, S & Prestidge, CA 2016, 'Lipophilic prodrugs of SN38: synthesis and in vitro characterization toward oral chemotherapy', Molecular Pharmaceutics, v. 13, no. 1, pp. 287-294. Diab, S, Li, P, Basnet, SK, Lu, J, Yu, M, Albrecht, H, Milne, RW & Wang, S 2016, 'Unveiling new chemical scaffolds as Mnk inhibitors', Future Medicinal Chemistry, v. 8, no. 3, pp. 271-285. Basnet, SK, Diab, S, Schmid, R, Yu, M, Yang, Y, Gillam, TA, Teo, T, Li, P, Peat, T, Albrecht, H & Wang, S 2015, 'Identification of a highly conserved allosteric binding site on Mnk1 and Mnk2', Molecular Pharmacology, v. 88, no. 5, pp. 935-948. Kumarasiri, M, Teo, THS & Wang, S 2015, 'Dynamical insights of Mnk2 kinase activation by phosphorylation to facilitate inhibitor discovery', Future Medicinal Chemistry. Le, BT, Kumarasiri, M, Adams, J, Yu, M, Milne, RW, Sykes, MJ & Wang, S 2015, 'Targeting Pim kinases for cancer treatment: Opportunities and challenges', Future Medicinal Chemistry, v. 7, no. 1, pp. 35-53. Lu, T, Laughton, C, Wang, S & Bradshaw, T 2015, 'In vitro antitumor mechanism of (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)methanesulfonamide', Molecular Pharmacology. Teo, T, Yang, Y, Yu, M, SK, Gillam, T, Hou, J, Schmid, R, Kumarasiri, M, Diab, S, Albrecht, H, Sykes, M & Wang, S 2015, 'An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis', European Journal of Medicinal Chemistry, v. 103, pp. 539-550. Teo, THS, Lam, FK, Yu, M, YANG, Y, KC Basnet, S, Albrecht, H, Sykes, MJ & Wang, S 2015, 'Pharmacologic inhibition of MNKs in acute myeloid leukemia', Molecular Pharmacology, v. 88, no. 2, pp. 380-389. Yu, M, Li, P, KC Basnet, S, Kumarasiri, M, Al Haj Diab, S, Teo, THS, Albrecht, H & Wang, S 2015, 'Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d[pyrimidine derivatives as potent Mnk inhibitors: Synthesis, structure-activity relationship analysis and biological evaluation', European Journal of Medicinal Chemistry, v. 95, pp. 116-126. Al Haj Diab, S, Teo, THS, Kumarasiri, M, Li, P, Yu, M, Lam, FK, KC Basnet, S, Sykes, MJ, Albrecht, H, Milne, RW & Wang, S 2014, 'Discovery of 5-( 2-( Phenylamino) pyrimidin-4-yl) thiazol2( 3H)- one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation', ChemMedChem: chemistry enabling drug discovery, v. 9, no. 5, pp. 962-972. Diab, S, Kumarasiri, M, Yu, M, Teo, T, Proud, C, Milne, R & Wang, S 2014, 'MAP kinase-interacting kinases: emerging targets against cancer', Chemistry and Biology, v. 21, no. 4, pp. 441-452. Lam, FK, Abdullahi, A, Shao, H, Teo, THS, Adams, JRJ, Li, P, Bradshaw, T, Fischer, P, Walsby, E, Pepper, C, Chen, Y, Ding, J & Wang, S 2014, 'Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73', Oncotarget, v. 5, no. 17, pp. 7691-7704. Lu, T, Goh, AW, Yu, M, Adams, J, Lam, F, Teo, T, Li, P, Noll, B, Zhong, L, Diab, S, Chahrour, O, Hu, A, Abbas, AY, Liu, X, Huang, S, Sumby, CJ, Milne, R, Midgley, C & Wang, S 2014, 'Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities', Journal of Medicinal Chemistry, v. 57, no. 6, pp. 2275-2291. Teo, THS, Yu, M, Yang, Y, Gillam, TA, Lam, FK, Sykes, MJ & Wang, S 2014, 'Pharmacologic co-inhibition of Mnks and mTORC1 synergistically suppresses proliferation and perturbs cell cycle progression in blast crisis-chronic myeloid leukemia cells', Cancer Letters, v. 357, pp. 612-623. Walsby, E, Pratt, C, Shao, H, Abbas, A, Fischer, P, Bradshaw, T, Brennan, P, Fegan, C, Wang, S & Pepper, C 2014, 'A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine', Oncotarget, v. 5, no. 2, pp. 375-385. Hou, J, Teo, THS, Sykes, MJ & Wang, S 2013, 'Insights into the importance of DFD-motif and insertion I1 in stabilizing the DFD-out conformation of Mnk2 kinase', ACS Medicinal Chemistry Letters, v. 4, no. 8, pp. 736-741. Shao, H, Shi, S, Foley, DW, Lam, FK, Abbas, A, Liu, X, Huang, S, Jiang, X, Baharin, N, Fischer, P & Wang, S 2013, 'Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents', European Journal of Medicinal Chemistry, v. 70, pp. 447-455. Shao, H, Shi, S, Huang, S, Hole, AJ, Abbas, A, Baumli, S, Liu, X, Lam, FK, Foley, DW, Fischer, P, Noble, M, Endicott, JA, Pepper, C & Wang, S 2013, 'Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure-Activity Relationship, and Anticancer Activities', Journal of Medicinal Chemistry, v. 56, no. 3, pp. 640-659. Alkahtani, HM, Abbas, A & Wang, S 2012, 'Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents', Bioorganic and Medicinal Chemistry Letters, v. 22, no. 3, pp. 1317-1321. Hole, AJ, Baumli, S, Shao, H, Shi, S, Huang, S, Pepper, C, Fischer, P, Wang, S, Endicott, JA & Noble, M 2012, 'Comparative Structural and Functional Studies of 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 Inhibitors Suggest the Basis for Isotype Selectivity', Journal of Medicinal Chemistry, v. 56, no. 3, pp. 660-670.