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Abuhelwa, AY, Mudge, S, Hayes, D, Upton, RN & Foster, DJ 2016, 'Population In Vitro-In Vivo correlation model linking gastrointestinal transit time, pH, and pharmacokinetics: itraconazole as a model drug', Pharmaceutical Research, v. 33, no. 7, pp. 1782-1794. Kn?sgaard, KR, Foster, DJR, Kreilgaard, M, Sverrisdóttir, E, Upton, RN & van den Anker, JN 2016, 'Pharmacokinetic models of morphine and its metabolites in neonates:: Systematic comparisons of models from the literature, and development of a new meta-model', European Journal of Pharmaceutical Sciences, v. 92, pp. 117-130. Mould, D, DG & Upton, RN 2016, 'Clinical decision support tools: the evolution of a revolution', Clinical Pharmacology and Therapeutics, v.99, no. 4, pp. 405 - 418. Olsen, B, Foster, DJR, Upton, RN, OA, Ross, JR, DJ, SH, Drewes, AM & Kreilgaard, M 2016, 'Modelling the PKPD of oxycodone in experimental pain - impact of opioid receptor polymorphisms', European Journal of Pharmaceutical Sciences, v. 86, pp. 41 - 49. Wojciechowski, J, Wiese, MD, Proudman, SM, Foster, DJ & Upton, RN 2016, 'A model-based evaluation of single metrics for discriminating changes in rheumatoid arthritis disease activity', British Journal of Clinical Pharmacology, v. 81, no. 6, pp. 1046-1057. Abuhelwa, AY, Foster, DJ, Mudge, S, Hayes, D & Upton, RN 2015, 'Population pharmacokinetic modeling of itraconazole and hydroxyitraconazole for oral suba-itraconazole and sporanox capsule formulations in healthy subjects in fed and fasted states', Antimicrobial Agents and Chemotherapy, v. 59, no. 9, pp. 5681-5696. Abuhelwa, AY, Foster, DJR & Upton, RN 2015, 'ADVAN-style analytical solutions for common pharmacokinetic models', Journal of Pharmacological and Toxicological Methods, v. 73, pp. 42-48. Doolette, D, Upton, RN & Grant, C 2015, 'Altering blood flow does not reveal differences between nitrogen and helium kinetics in brain or in skeletal miracle in sheep', Journal of Applied Physiology. Hopkins, AM, Foster, D, Wiese, M & Upton, R 2015, 'Response to Physiologically Based Pharmacokinetic Model for Prediction of Leflunomide and Teriflunomide - Should Consideration Be Given to Cannalicular Efflux Transporters?', CPT: Pharmacometrics and Systems Pharmacology, v. 4, pp. 464. Hopkins, AM, Wiese, MD, Proudman, SM, O'Doherty, C, Foster, DJR & Upton, RN 2015, 'Semiphysiologically based pharmacokinetic model of leflunomide disposition in rheumatoid arthritis patients', CPT: Pharmacometrics & Systems Pharmacology. Hopkins, AM, Wiese, MD, Proudman, SM, O'Doherty, CE, Upton, RN & Foster, DJR 2015, 'Genetic polymorphism of CYP1A2 but not total or free teriflunomide concentrations is associated with leflunomide cessation in rheumatoid arthritis', British Journal of Clinical Pharmacology, v. 81, no. 1, pp. 113-123. Wojciechowski, J, Wiese, MD, Proudman, SM, Foster, DJR & Upton, RN 2015, 'A Population Model of Early Rheumatoid Arthritis Disease Activity during treatment with Methotrexate, Sulfasalazine and Hydroxychloroquine', British Journal of Clinical Pharmacology, in press. Wojciechowski, JA, Hopkins, AM & Upton, RN 2015, 'Interactive pharmacometric applications using R and the Shiny package', CPT: Pharmacometrics & Systems Pharmacology. Dooney, N, Sundararajan, K, Ramkumar, T, Somogyi, A, Upton, RN, Ong, J, O'Connor, S, Chapman, M & Ludbrook, G 2014, 'Pharmacokinetics of tramadol after subcutaneous administration in a critically ill population and in a healthy cohort', BMC Anesthesiology, v. 14, article no. 33. Hopkins, AM, King, CE, Foster, DJR, Suppiah, V, Upton, RN, Spargo, L, Cleland, L, Proudman, SM & Wiese, MD 2014, 'The rheumatoid arthritis susceptibility polymorphism PTPN22 C1858T is not associated with leflunomide response or toxicity', Journal of Clinical Pharmacy and Therapeutics, v. 39, no. 5, pp. 555-560. Hopkins, AM, O'Doherty, CE, Foster, DJR, Upton, RN, Proudman, SM & Wiese, MD 2014, 'Individualization of leflunomide dosing in rheumatoid arthritis patients', Personalized medicine, v. 11, no. 4, pp. 449-461. Juul, R, Foster, DJ, Upton, R, Andresen, T, Graversen, C, Drewes, AM, Christrup, L & Kreilgaard, M 2014, 'Pharmacodynamic Modelling of Placebo and Buprenorphine Effects on Event-Related Potentials in Experimental Pain', Basic and Clinical Pharmacology and Toxicology, v. 115, no. 4 , pp.343-351. Mould, D, Upton, RN & Wojciechowski, J 2014, 'Dashboard Systems: Implementing Pharmacometrics from Bench to Bedside', American Association of Pharmaceutical Scientists (AAPS) Journal, v. 16, no. 5, pp. 925-937. Ravn, P, Foster, DJ, Kreilgaard, M, Christrup, L, Werner, MU, Secher, EL, Skram, U & Upton, R 2014, 'Pharmacokinetic-pharmacodynamic modelling of the analgesic and antihyperalgesic effects of morphine after intravenous infusion in human volunteers', Basic and Clinical Pharmacology and Toxicology, v. 115, no. 3, pp. 257-267. Reuter, SE, Upton, RN, Evans, AM, Navaratnam, V & Olliaro, PL 2014, 'Population pharmacokinetics of orally administered mefloquine in health volunteers and patients with uncomplicated Plasmodium falciparum malara', Journal of Antimicrobial Chemotherapy, v. 70, no. 3, pp. 868-876.