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（1）Junwei Wang, Hui Li, Guangchao He, Zhaoxing Chu, Kewen Peng, Yiran Ge, Qihua Zhu*, Yungen Xu*. Discovery of Novel Dual Poly(ADP-ribose)polymerase and Phosphoinositide 3Kinase Inhibitors as a Promising Strategy for Cancer Therapy. Journal of Medicinal Chemistry, 2020,63(1):122-139.
（2）Jian Yang#, Fantian Zeng#, Xiaofang Li, Chongzhao Ran, Yungen Xu*, Yuyan Li*. Highly Specific Detection of Aβ Oligomers in Early Alzheimer’s Disease by Near-infrared Fluorescent Probe with a “V-shaped” Spatial Conformation. Chemical Communications, 2020, 56(4):583-586.
（3）Jian Yang#, Fantian Zeng#, Yiran Ge, Kewen Peng, Xiaofang Li, Yuyan Li*, Yungen Xu*. Development of Near-Infrared Fluorescent Probes for Use in Alzheimer’s Disease Diagnosis. Bioconjugate Chemistry. 2020,31(1):2-15.
（4）Dezhong Ji#, Lingzhi Zhang#, Qihua Zhu*, Ying Bai, Yaoyao Wu, Yungen Xu*. Discovery of potent, orally bioavailable ERK1/2 inhibitors with isoindolin-1-one structure by structure-based drug design. European Journal of Medicinal Chemistry, 2019,164:334-341.
（5）Peng Kewen, Bai Ying, Zhu Qihua, Hu Bin, Xu Yungen*. Targeting VEGF-neuropilin interactions: a promising antitumor strategy. Drug Discovery Today, 2019, 24(2): 656-664.
（6）Tingting Liang#, Xin He#, Dezhong Ji, Huanhuan Wu, Yizhu Xu, Yuyan Li, Zhibin Wang, Yungen Xu*, Qihua Zhu*. Transition Metal-Free C5 Tosyloxylation of 8-Aminoquinolines with Phenyliodine Bistrifluoroacetate and Substituted 1,2-Disulfonyl Hydrazides. European Journal of Organic Chemistry, 2019,14:2513-2519.
（7）Shaochi Wang#, Yun Yang#, Jing Liu, Aidou Jiang, Zhaoxing Chu, Siying Chen, Guoqing Gong*, Guangwei He, Yungen Xu*, Qihua Zhu*. Discovery of Novel Limonin Derivatives as Potent Anti-inflammatory and Analgesic Agents. Chinese Journal of Natural Medicines, 2018,16(3):231-240.
（8）Shuwei Jin#, Jingqi Wang#, Siying Chen, Aidou Jiang, Meiling Jiang, Yourui Su, Wei Yan, Yungen Xu*, Guoqing Gong*. A novel limonin derivate modulates inflammatory response by suppressing the TLR4/NF-κB signalling pathway. Biomedicine & Pharmacotherapy, 2018,100:501-508.
（9）Qiufang Chen, Shuang Cui, Huiliang Shen, Xiang Chen, Yunzhan Li, Qian Wu, Yungen Xu*, Guoqing Gong*. Dual inhibition of HY023016 based on binding properties of platelet membrane receptor subunit glycoprotein Ibα and thrombin exosites. European Journal of Pharmacology, 2018,822:51-58.
（10）Lingzhi Zhang#, Tantan Bu#, Xiaobo Bao, Tingting Liang, Yiran Ge, Yungen Xu*, Qihua Zhu*. Design, synthesis and biological evaluation of novel 3H-imidazole [4,5-b] pyridine derivatives as selective mTOR inhibitors. Bioorganic & Medicinal Chemistry Letters,2017,27(15):3395-3398.
（11）Haiqi Zhang, Feihu Gong, Jiqing Ye, Chi Zhang, Xiaohong Yue，Chuangui Li, Yungen Xu*, Liping Sun*. Design and discovery of 4-anilinoquinazoline-urea derivatives as dual TK inhibitors of EGFR and VEGFR-2. European Journal of Medicinal Chemistry, 2017,125:245-254.
（12）Xin He#, Yizhu Xu#, Lingxuan Kong, Huanhuan Wu, Dezhong Ji, Zhibin Wang, Yungen Xu*, Qihua Zhu*. Copper(I) and N-fluorobenzenesulfonimide-mediated direct regioselective halogenation of 8-amidoquinolines on the C5 position. Organic Chemistry Frontiers, 2017,4(6):1046-1050.
（13）Junwei Wang#, Qiao Song#, Anhua Xu, Yu Bao, Yungen Xu*, Qihua Zhu*, Design, synthesis and biological evaluation of aminobenzyloxyarylamide derivatives as selective k opioid receptor antagonists. European Journal of Medicinal Chemistry, 2017,130(1): 15–25.
（14）Dongxing Chen#, Jinyu Shi#, Jing Liu, Xueying Zhang, Xiaoying Deng, Yanyan Yang, Shuang Cui, Qihua Zhu*, Guoqing Gong, Yungen Xu*. Design, synthesis and antithrombotic evaluation of novel non-peptide thrombin inhibitors. Bioorganic & Medicinal Chemistry, 2017, 25(2):458-470.
（15）Hui Li, Yan Hu, Xueyan Wang, Guangwei He, Yungen Xu*, Qihua Zhu*.Novel tricyclic poly (ADP-ribose) polymerase-1/2 inhibitors with potent anticancer chemopotentiating activity: Design, synthesis and biological evaluation. Bioorganic & Medicinal Chemistry Letters, 2016, 24 (19):4731-4740.
（16）Jian Yang, Jing Yang, Steven H. Liang, Yungen Xu*, Anna Moore, Chongzhao Ran*. Imaging hydrogen peroxide in Alzheimer’s disease via cascade signal amplification. Scientific Reports, 2016, 6: 35613.
（17）Junwei Wang, Xuyan Wang, Hui Li, Dezhong Ji, Yuyan Li,Yungen Xu*, Qihua Zhu*. Design, synthesis and biological evaluation of novel 5-fluoro-1H-benzimidazole-4-carboxamide derivatives as potent PARP-1 inhibitors. Bioorganic & Medicinal Chemistry Letters, 2016, 26:4127–4132.
（18）Dezhong Ji#, Xin He#, Yizhu Xu, Ziyue Xu, Yuchen Bian, Weixing Liu, Qihua Zhu*, Yungen Xu*. Metal-Free Remote CH Bond Amidation of 8-Amidoquinolines on the C5 Position under Mild Conditions. Organic Letters, 2016, 18(18):4478-4481.
（19）Ting Guo#, Zongjie Gan#, Jie Chen, Dechuan Wang, Ling He, Qiao Song, Yungen Xu*. Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral κ-opioid receptor agonists. Bioorganic & Medicinal Chemistry, 2016, 24(13): 2964-2970.
（20）Fanwei Peng#, Ji Xuan#, Tingting Wu, Jiayu Xue, Ziwei Ren, Dake Liu, Xiuqi Wang, Xinhang Chen, Jiawei Zhang, Yungen Xu*, Lei Shi*. Design, synthesis and biological evaluation of N-phenylquinazolin-4-amine hybrids as dual inhibitors of VEGFR-2 and HDAC. European Journal of Medicinal Chemistry, 2016, 109:1-12.
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