近期论文
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1.Omid Tavana, Dawei Li, Chao Dai, Gonzalo Lopez, Debarshi Banerjee, Ning Kon, Chao Chen, Andrea Califano, Darrell J Yamashiro, Hongbin Sun, Wei Gu *. Destabilizing N-Myc by HAUSP Inhibition Acts as a Potential Therapy for Neuroblastomas. Nature Medicine 2016, accepted.
2.Jin-Zheng Wang, Jin Zhou, Chang Xu, Hongbin Sun*, László Kürti* and Qing-Long Xu.* Symmetry in Cascade Chirality-Transfer Processes: A Catalytic Atroposelective Direct Arylation Approach to BINOL Derivatives. J. Am. Chem. Soc. 2016, 138, 5202-5205.
3.Zhuang Song, Yizhou Wu, Tao Xin, Xiaoan Wen, Hongbin Sun,* and Qing-Long Xu.* Rh(II)-Catalyzed Formal N-S Bond Insertion Reaction of Aryldiazoacetates into N-Phenyl-Sulfenyl Phthalimide. Chemical Communications 2016, 52, 6079-6082.
4.Ming Yang, Xiaowen Yang, Hongbin Sun, Ang Li*. Total Synthesis of Ileabethoxazole, Pseudopteroxazole, and seco-Pseudopteroxazole. Angewandte Chemie International Edition 2016, 55, 2851-2855.
5.Xiantao Lei, Hong-Yan Xie, Chang Xu, Xiaoyu Liu, Xiaoan Wen, Hongbin Sun*, Qing-Long Xu*. Dearomatization of Indoles Derivatives via Pd-Catalyzed C-H Bond Functionalization of Pyrroles: Convenient Construction of Spiroindolenines. Advanced Synthesis & Catalysis 2016, 358, 1892-1896 (Very Important Publication).
6.Chao Lin, Le Zhen, Yong Cheng, Hong-Jin Du, Hui Zhao, Xiaoan Wen, Lingyi Kong, Qing-Long Xu*, Hongbin Sun*. Visible-light Induced Isoindoles Formation to Trigger Intermocular Diels-Alder Reactions In the Presence of Air. Organic letters 2015, 17, 2684-2687.
7.Xiaowei Sun, Xiaoan Wen, Yan-yan Chen, Chen Shi, Chengzhe Gao, Yong Wu, Li-jun Wang, Xiu-hong Yang*, Hongbin Sun*. Discovery of highly potent renin inhibitors potentially interacting with the S3′subsite of renin. European Journal of Medicinal Chemistry 2015, 103, 269-288.
8.Xueli Zhang, Yanli Tian, Can Zhang, Xiaoyu Tian, Alana W. Ross, Robert D. Moir, Hongbin Sun, Rudolph E. Tanzi, Anna Moore, Chongzhao Ran*. Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease. PNAS 2015, 112, 9734-9739.
9.Peng-Fei Wang, Chun-Huan Jiang, Xiaoan Wen, Qing-Long Xu,* Hongbin Sun.*C-H Bond Functionalization via [1,5]-Hydride Shift/Cyclization Sequence: Approach to Spiroindolenines. Journal of Organic Chemistry 2015, 80, 1155-1162.
10.Yong-Zhi Chang, Ming-Lei Li, Wen-Feng Zhao, Xiaoan Wen, Hongbin Sun,* Qing-Long Xu*. Construction of Oxadiazepines via Lewis Acid-Catalyzed Tandem 1,5-Hydride Shift/Cyclization. Journal of Organic Chemistry 2015, 80, 9620-9627.
11.Fan Zhang, Hengzhi Sun, Zhuang Song, Shuxi Zhou, Xiaoan Wen, Qing-Long Xu,* Hongbin Sun.* Stereoselective Synthesis of Arylglycine Derivatives via a Palladium-Catalyzed alpha-Arylation of Chiral Nickel (II) Glycinate. Journal of Organic Chemistry 2015, 80, 4459−4464.
12.Zengwei Lai, Chunhong Li, Jun Liu, Lingyi Kong, Xiaoan Wen,* Hongbin Sun.* Discovery of Highly Potent DPP-4 Inhibitors by Hybrid Compound Design Based on Linagliptin and Alogliptin. European Journal of Medicinal Chemistry 2014, 83, 547-560.
13.Xueli Zhang, Yanli Tian, Zeng Li, Xiaoyu Tian, Hongbin Sun, Hong Liu, Anna Moore, Chongzhao Ran*. Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid Beta species in Alzheimer's disease. J. Am. Chem. Soc. 2013, 135, 16397-409.
14.Jiaqi Shan, Boyu Zhang, Yaoqiu Zhu, Bo Jiao, Weiyi Zheng, Xiaowei Qi, Yanchun Gong,Fang Yuan, Fusheng Lv, Hongbin Sun.* Overcoming Clopidogrel Resistance: Discovery of Vicagrel as a Highly Potent and Orally Bioavailable Antiplatelet agent. Journal of Medicinal Chemistry 2012, 55, 3342–3352.（获Nature旗下刊物SciBX的亮点报道）
15.Huaming Sheng, Hongbin Sun.* Synthesis, Biology and Clinical Significance of Pentacyclic Triterpenes: a Multi-target Approach to Prevention and Treatment of Metabolic and Vascular Diseases.Natural Product Reports 2011, 28, 543-593.
16.Zhangyu Yao, Xueying Wei, Xiaoming Wu, Jonathan L. Katz, Theresa Kopajtic, Nigel H. Greig, Hongbin Sun.* Preparation and Evaluation of Tetrabenazine Enantiomers and All Eight Stereoisomers of Dihydrotetrabenazine as VMAT2 Inhibitors. European Journal of Medicinal Chemistry 2011, 46, 1841-1848.
17.Zhongjie Liang, Liying Zhang, Lianchun Li, Jun Liu, Honglin Li, Luyong Zhang，Keguang Cheng, Xiaoan Wen, Pu Zhang, Jia Hao, Yanchun Gong, Xia Zhang, Jun Chen, Hong Liu, Cheng Luo, Hualiang Jiang, Hongbin Sun.* Pentacyclic Triterpenes Derivatives as Potent Inhibitors against Glycogen Phosphorylase: the Receptor-Based 3D-QSAR Guided Inhibitor Optimization. European Journal of Medicinal Chemistry 2011, 46, 2011-2021.
18.Pu Zhang, Jia Hao, Jun Liu, Qian Lu, Huaming Sheng, Luyong Zhang,Hongbin Sun.* Synthesis and biological evaluation of 3-deoxy-pentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase. Journal of Natural Products2009, 72, 1414–1418.
19.Xiaoan Wen, Hongbin Sun,* Jun Liu, Keguang Cheng, Pu Zhang, Liying Zhang,Jia Hao, Luyong Zhang, Peizhou Ni, Spyros E. Zographos, Demetres D. Leonidas, Kyra-Melinda Alexacou, Thanasis Gimisis, Joseph M. Hayes, Nikos G. Oikonomakos.* Naturally Occurring Pentacyclic Triterpenes as Inhibitors of Glycogen Phosphorylase: Synthesis, Structure-Activity Relationships and X-ray Crystallographic Studies. Journal of Medicinal Chemistry 2008, 51, 3540-3554.
20.Xiaoan Wen, Pu Zhang, Jun Liu, Luyong Zhang, Xiaoming Wu, Peizhou Ni, Hongbin Sun.* Pentacyclic Triterpenes. Part 2: Synthesis and biological activity of maslinic acid derivatives as inhibitors of glycogen phosphorylase. Bioorganic & Medicinal Chemistry Letters 2006, 16, 722-726. (“Bioorganic and Medicinal Chemistry Letters” Most Cited Paper 2006-2009 Award)
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