个人简介
王洁,女,博士研究生,2018年毕业于沈阳药科大学,在上海交通大学医学院附属仁济医院海洋药物研究重点实验室从事海洋天然活性成分的研究。同年任教于浙江海洋大学。
参与科研项目:
1、国家自然科学基金应急管理项目,81741149,海绵共附生Trichoderma属真菌中抗MRSA活性肽类化合物的发现及其构效关系研究,2018.01.01-2018.12.31,30万元。(已结题)
2、国家自然科学联合重点项目,U1605221,台海海绵共生体中抗肿瘤干细胞激酶抑制剂的发现及作用机制,2017.01.01-2019.12.31,215万元。
近期论文
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1. Jie Wang, Feng-Rong Mu, Wei-Hua Jiao, Jian Huang, Li-Li Hong, Fan Yang, Ying Xu,
Shu-Ping Wang, Fan Sun, Hou-Wen Lin. Meroterpenoids with protein tyrosine phosphatase 1B inhibitory activity from a Hyrtios sp. marine sponge. J Nat Prod, 2017, 80(9), 2509-2514. (IF = 3.281 in 2017)
2. Jie Wang, Li-Yun Liu, Lei Liu, Kai-Xuan Zhan, Wei-Hua, Jiao, Hou-Wen Lin. Pellynols M-O, cytotoxic polyacetylenic alcohols from a Niphates sp. marine sponge, Tetrahedron, 2018, 74, 3701-3706. (IF = 2.377 in 2018)
3. Lei Li, Jie Wang, Yong-Jun Zhou, Hou-Wen Lin,Yan-Hua Lu. Streptomyces reniochalinae sp. nov. and Streptomyces diacarni sp. nov. from marine sponges, Int J Syst Evol Microbiol, 2018, 69(1):99-104. (IF = 1.932 in 2018)
4. Li-Li Hong, Hao-Bing Yu, Jie Wang, Wei-Hua Jiao, Bao-Hui Cheng, Fan Yang, Yong-Jun Zhou, Bin-Bin Gu, Shao-Jiang Song, Hou-Wen Lin. Unusual anti-allergic diterpenoids from the marine sponge Hippospongia lachne. Sci Rep, 2017, 7:43138. (IF = 4.259 in 2017)
5. Wei-Hua Jiao, Ting-Ting Xu, Feng Zhao, Hao Gao, Guo-Hua Shi, Jie Wang, Li-Li Hong, Hao-Bing Yu, Yu-Shan Li, Fan Yang, Hou-Wen Lin. Dysifragilones A–C, unusual sesquiterpene aminoquinones and inhibitors of NO production from the South China Sea sponge Dysidea fragilis . Eur. J. Org. Chem, 2015, 960-966. (IF = 3.068 in 2015)
6. 王洁, 焦伟华, 黄健, 王金辉, 林厚文. Dactylospongia 属海绵的化学成分及生物活性研究进展[J]. 中国海洋药物, 2016, 35 (2): 103-110.
7. 王书云, 王洁, 黄健, 李国玉, 王金辉. 蚝贝钙片中微量元素的含量测定研究[J]. 中国现代中药, 2014, 16(2), 141-143.