Cheesman, Matthew - University of Queensland - School of Biomedical Sciences

研究领域

Online technology-based learning and engagement Dr Cheesman’s research interests concern the development of virtual and online computing technologies for use in student learning and improved lecturer feedback. Projects have included the design of a virtual laboratory class, and the use of digital ink in student examination and marking. Current work is based on the design and implementation of online learning modules that feature student achievement and leaderboards mixed with learning tasks that promote development and retention of knowledge.Cytochrome P450 Other ongoing projects involve collaborations with two external laboratory research groups studying the involvement of cytochrome P450 enzymes in the metabolism of insecticides and of medicinal plant compounds.

近期论文

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Cheesman, Matthew J., Chunduri, Prasad, Manchadi, Mary Louise, Colthorpe, Kay and Matthews, Ben (2015) Student Interaction with a Computer Tablet Exam Application Replicating the Traditional Paper Exam. Mobile Computing, 4 10-21. doi:10.14355/mc.2015.04.002 Cheesman, Matthew J., Chen, Steven, Manchadi, Mary-Louise, Jacob, Teague, Minchin, Rodney F. and Tregloan, Peter A. (2014) Implementation of a Virtual Laboratory Practical Class (VLPC) module in pharmacology education. Pharmacognosy Communications, 4 1: 2-10. doi:10.5530/pc.2014.1.2 Cheesman, Matthew, Williams, Mark, Chunduri, Prasad, Manchadi, Mary-Louise and Tregloan, Peter (2014). Analysis of student behavioural patterns in the use of a virtual laboratory: A comparison of cohorts from two different disciplines. In: Proceedings of the Australian Conference on Science and Mathematics Education. Australian Conference on Science and Mathematics Education, Sydney NSW Australia, (16-16). 29-30 September 2014. Cheesman, Matthew J., Traylor, Matthew. J., Hilton, Margaret E., Richards, Katelyn E., Taylor, Matthew C., Daborn, Philip J., Russell, Robyn J., Gillam, Elizabeth M. J. and Oakeshott, John G. (2013) Soluble and membrane-bound Drosophila melanogaster CYP6G1 expressed in Escherichia coli: purification, activity, and binding properties toward multiple pesticides. Insect Biochemistry and Molecular Biology, 43 5: 455-465. doi:10.1016/j.ibmb.2013.02.003 Chen, S., Zornig, J., Chester, N., Tregloan, P. A., Cody, A. and Cheesman, M. J. (2012). VLPC: a HTML5 pharmacology virtual laboratory. In: 2012 9th International Conference on Remote Engineering and Virtual Instrumentation (REV). 2012 9th International Conference on Remote Engineering and Virtual Instrumentation (REV), Bilbao, Spain, (). 4-6 July 2012. doi:10.1109/REV.2012.6293114 Roberts, Arthur G., Cheesman, Matthew J., Primak, Andrew, Bowman, Michael K., Atkins, William M. and Rettie, Allan E. (2010) Intramolecular heme ligation of the cytochrome P450 2C9 R108H mutant demonstrates pronounced conformational flexibility of the B-C loop region: Implications for substrate binding. Biochemistry, 49 40: 8700-8708. doi:10.1021/bi100911q Kaspera, Rüdiger, Naraharisetti, Suresh B., Tamraz, Bani, Sahele, Tariku, Cheesman, Matthew J., Kwok, Pui-Yan, Marciante, Kristin, Heckbert, Susan R., Psaty, Bruce M. and Totah, Rheem A. (2010) Cerivastatin in vitro metabolism by CYP2C8 variants found in patients experiencing rhabdomyolysis. Pharmacogenetics And Genomics, 20 10: 619-629. doi:10.1097/FPC.0b013e32833ecace Tatheer, Naqvi, Cheesman, Matthew J., Williams, Michelle R., Campell, Peter M., Ahmed, Safia, Russell, Robyn J., Scott, Collin and Oakeshott, John G. (2009) Heterologous expression of the methyl carbamate-degrading hydrolase MCD. Journal of Biotechnology, 144 2: 89-95. doi:10.1016/j.jbiotec.2009.09.009 Scott, Colin, Pandey, Gunjan, Hartley, Carol J., Jackson, Colin J., Cheesman, Matthew J., Taylor, Matthew C., Pandey, Rinku, Khurana, Jeevan L., Teese, Mark, Coppin, Chris W., Weir, Kahli M., Jain, Rakesh K., Lal, Rup, Russell, Robyn J. and Oakeshott, John G. (2008) The enzymatic basis for pesticide bioremediation. Indian Journal of Microbiology, 48 1: 65-79. doi:10.1007/s12088-008-0007-4 Cheesman, Matthew J., Horne, Irene, Weir, Kahli M., Pandey, Gunjun, Williams, Michelle R., Scott, Colin, Russell, Robyn J. and Oakeshott, John G. (2007). Carbamate pesticides and their biological degradation: prospects for enzymatic bioremediation. In Ivan R. Kennedy, Keith R. Solomon, Shirley J. Gee, Angus N. Crossan, Shuo Wang and Francisco Sanchez-Bayo (Ed.), Rational environmental management of agrochemicals (pp. 288-305) Washington, D.C.: American Chemical Society. doi:10.1021/bk-2007-0966.ch018 Cheesman, Matthew J., Kneller, M. Byron and Rettie, Allan E. (2003) Critical role of histidine residues in cyclohexanone monooxygenase expression, cofactor binding and catalysis. Chemico-Biological Interactions, 146 2: 157-164. doi:10.1016/S0009-2797(03)00105-4 Cheesman, Matthew J., Baer, Brian R., Zheng, Yi-Min, Gillam, Elizabeth M. J. and Rettie, Allan E. (2003) Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group. Archives of Biochemistry And Biophysics, 416 1: 17-24. doi:10.1016/S0003-9861(03)00278-9