个人简介

王艳，女，汉族，辽宁师范大学生命科学院学士，中国科学院华南植物研究所硕士，中国科学院南海海洋研究所博士。2006-2007年，在香港大学植物系任研究助理，2007-2011年，在中国科学院烟台海岸带研究所任助理研究员，于2012年晋升为副研究员。目前已在Biomass & Bioenergy，Applied Microbiology and Biotechnology，Process Biochemistry，BMC Genomics，Journal of Applied Phycology，Journal of Chemical Technology and Biotechnology，Biotechnology Letters，World Journal of Microbiology & Biotechnology等SCI刊物上发表论文十余篇，申请国际发明专利1项（已授权），国内发明专利9项。作为总负责人承担的科研项目包括国家自然科学基金、国家海藻工程技术研究中心开放基金、烟台市科技发展计划基金、中科院烟台海岸带研究所前沿领域基金等。

研究领域

微藻产品工程

微藻产品工程。主要研究自然界富含高附加值天然产物的微藻的分布及生态和生理条件。同时研究这些微藻的功能性成分，并验证其生理活性及作用机制。探索可适合预防乃至治疗癌症、心血管疾病、高血压、糖尿病、老年痴呆症等功能性保健食品。采用生化工程的原理和手段，研究功能微藻人工养殖过程的调控及优化、数学模拟、产物回收及分离提纯、规模化生产及评价等。

近期论文

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[1] Li, JD.,Min, J.,Wang, Y.,Chen, WW.,Kong, YC.,...&Hu, XK.(2020).Engineering Burkholderia xenovorans LB400 BphA through Site-Directed Mutagenesis at Position 283.APPLIED AND ENVIRONMENTAL MICROBIOLOGY,86(19),.. [2] Wang, Y,Zhang, LW,&Chen, LX.(2020).Glutathione Peroxidase-Activatable Two-Photon Ratiometric Fluorescent Probe for Redox Mechanism Research in Aging and Mercury Exposure Mice Models.ANALYTICAL CHEMISTRY,92(2),1997-2004. [3] Gao, M.,Zhang, X.,Wang, Y.,Liu, QL.,Yu, FB.,...&Chen, LX.(2019).Sequential Detection of Superoxide Anion and Hydrogen Polysulfides under Hypoxic Stress via a Spectral-Response-Separated Fluorescent Probe Functioned with a Nitrobenzene Derivative.ANALYTICAL CHEMISTRY,91(12),7774-7781. [4] Wang, Y,Zhang, LW,Zhang, SZ,Liu, Z,&Chen, LX.(2019).High Spatiotemporal Resolution Observation of Glutathione Hydropersulfides in Living Cells and Tissue via a Two-Photon Ratiometric Fluorescent Probe.ANALYTICAL CHEMISTRY,91(12),7812-7818. [5] Xu, RF,Wang, Y,You, HY,Zhang, LW,Wang, YQ,&Chen, LX.(2019).A near-infrared fluorescent probe for evaluating endogenous hydrogen peroxide during ischemia/reperfusion injury.ANALYST,144(8),2556-2564. [6] Chen, J.,Wang, Y.,Benemann, JR.,Zhang, XC.,Hu, HJ.,...&sqin@yic.ac.cn.(2016).Microalgal industry in China: challenges and prospects.JOURNAL OF APPLIED PHYCOLOGY,28(2),715-725. [7] Yu, Xiaona.,Cui, Hongli.,Cui, Yulin.,Wang, Yan.,Li, Xueqin.,...&sqin@yic.ac.cn.(2014).Gene cloning, sequence analysis, and expression profiles of a novel beta-ring carotenoid hydroxylase gene from the photoheterotrophic green alga Chlorella kessleri.MOLECULAR BIOLOGY REPORTS,41(11),7103-7113. [8] Cui, Hongli.,Yu, Xiaona.,Wang, Yan.,Cui, Yulin.,Li, Xueqin.,...&sqin@yic.ac.cn.(2014).Gene cloning and expression profile of a novel carotenoid hydroxylase (CYP97C) from the green alga Haematococcus pluvialis.JOURNAL OF APPLIED PHYCOLOGY,26(1),91-103. [9] Chen, Tao,Wang, Yan,Yan Wang,Yantai Institute of Coastal Zone Research for Sustainable Development, Chinese Academy of Sciences, Yantai, Shandong 264003, China Tel: +86535 2109151,&Fax: +86535 2109151 E-mail: ywang@yic.ac.cn.(2013).Optimized Astaxanthin Production in Chlorella zofingiensis under Dark Condition by Response Surface Methodology.FOOD SCIENCE AND BIOTECHNOLOGY,22(5),1343-1350. [10] Cui, Hongli.,Yu, Xiaona.,Wang, Yan.,Cui, Yulin.,Li, Xueqin.,...&Qin, Song.(2013).Evolutionary origins, molecular cloning and expression of carotenoid hydroxylases in eukaryotic photosynthetic algae.BMC GENOMICS,14. [11] Wang, Yan,Chen, Tao,&Qin, Song.(2013).Differential fatty acid profiles of Chlorella kessleri grown with organic materials.JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,88(4),651-657. [12] Wang Yan,&Yang Kaijing.(2013).Toxicity of single-walled carbon nanotubes on green microalga Chromochloris zofingiensis.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,31(2),306-311. [13] Wang, Yan,Liu, Zhengyi,&Qin, Song.(2013).Effects of iron on fatty acid and astaxanthin accumulation in mixotrophic Chromochloris zofingiensis.BIOTECHNOLOGY LETTERS,35(3),351-357. [14] Wang, Yan,Chen, Tao,&Qin, Song.(2012).Heterotrophic cultivation of Chlorella kessleri for fatty acids production by carbon and nitrogen supplements.BIOMASS & BIOENERGY,47,402-409. [15] Liu Dongyan,Jiang Jinjie,Wang Yan,Zhang Yong,&Di Baoping.(2012).Large scale northward expansion of warm water species Skeletonema tropicum (Bacillariophyceae) in China seas.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,30(4),519-527. [16] Chen, Tao,Wei, Dong,Chen, Gu,Wang, Yan,&Chen, Feng.(2009).EMPLOYMENT OF ORGANIC ACIDS TO ENHANCE ASTAXANTHIN FORMATION IN HETEROTROPHIC CHLORELLA ZOFINGIENSIS.JOURNAL OF FOOD PROCESSING AND PRESERVATION,33(2),271-284. [17] Wang, Yan,&Chen, Tao.(2008).The biosynthetic pathway of carotenoids in the astaxanthin-producing green alga Chlorella zofingiensis.WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,24(12),2927-2932. [18] Sun, Ni,Wang, Yan,Li, Yan-Tao,Huang, Jun-Chao,&Chen, Feng.(2008).Sugar-based growth, astaxanthin accumulation and carotenogenic transcription of heterotrophic Chlorella zofingiensis (Chlorophyta).PROCESS BIOCHEMISTRY,43(11),1288-1292. [19] Wang, Y.,&Peng, J..(2008).Growth-associated biosynthesis of astaxanthin in heterotrophic Chlorella zofingiensis (Chlorophyta).WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY,24(9),1915-1922.