个人简介

Professor Carmichael received his BSc and PhD from the University of Glasgow, Scotland in 1971 and 1974 respectively. He spent two years at the University of Amsterdam, the Netherlands on a British Royal Society Science Exchange Fellowship. He joined the Notre Dame Radiation Laboratory in 1976 and was appointed Director in 2004

研究领域

Physical/Analytical Chemistry

Ionizing radiation pervades our environment and affects all life on earth. The absorption of this impinging energy produces profound chemical and biochemical transformations in the materials irradiated. Professor Carmichael's research provides a fundamental molecular-level understanding of these radiation effects in matter. The work is performed in the Notre Dame Radiation Laboratory, the premier facility for radiation chemical research in the US, supported by the Chemical Sciences Division of Basic Energy Sciences at the US Department of Energy. The NDRL provides not only access to unique experimental tools but also outstanding research opportunities for focused interdisciplinary collaborations. Knowledge gained from this research provides the scientific basis for solving problems ranging from the chemical conversion of solar energy, through nuclear energy production, environmental waste management and remediation, to biomedical radiation therapy. 

 Specific topics currently under active investigation include: Radiation damage in protein crystallography Understanding and mitigating radiation damage during macromolecular crystallography at synchrotrons Electron-driven processes in condensed phases
 Excited species in water radiolysis; radical formation in irradiated organic liquids Radiation effects in heterogeneous systems and at interfaces 
Characterizing radiation chemistry at water - ceramic oxide interfaces Spin coupling in biomolecular NMR Probing conformational and chemical changes in carbohydrates

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Allan, E.G.; Kander, M.C.; Carmichael, I.; Garman, E.F. "To scavenge or not to scavenge, that is STILL the question." J. Synchrotron Radiat. 2013, 20, 23-36. Zhang, W.; Xiaosong, H.; Carmichael, I.; Serianni, A.S. "Methyl [C-13]Glucopyranosiduronic Acids: Effect of COOH Ionization and Exocyclic Structure on NMR Spin-Couplings." J. Org. Chem. 2012, 77 (21), 9521-9534. Zhang, W.; Carmichael, I.; Serianni, A.S. "Rearrangement of 3-Deoxy-D-erythro-hexos-2-ulose in Aqueous Solution: NMR Evidence of Intramolecular 1,2-Hydrogen Transfer." J. Org. Chem. 2011, 76 (20), 8151-8158. Lewandowska, A.; Carmichael, I.; Horner, G.; Hug, G.L.; Marciniak, B. "Steric effects on intramolecular reactivity in cyclic dipeptides: Conformational analysis validated by a combined MD/DFT approach." Chem. Phys. Lett. 2011, 512 (1-3), 123-128. De la Mora, E.; Carmichael, I.; Garman, E.F. "Effective scavenging at cryotemperatures: further increasing the dose tolerance of protein crystals." J. Synchrotron Radiat. 2011, 18, 346-357. Hu, X.; Zhang, W.; Carmichael, I; Serianni, A.S. "Amide Cis- Trans Isomerization in Aqueous Solutions of Methyl N-Formyl-D-glucosaminides and Methyl N-Acetyl-D-glucosaminides: Chemical Equilibria and Exchange Kinetics." J. Am. Chem. Soc. 2010, 132 (13), 4641-4652.