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Medicinal Chemistry Molecular Genetics and Genomics Nanotechnology and Materials Chemistry Science Education Structural Biology and Biochemistry

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Muller, D. A., Depelsenaire, A. C. I., Watterson, D., Zhang, J., Yukiko, S. R., Young, P. R. and Kendall, M. A. F. (2014). Targeted delivery of candidate dengue virus subunit vaccine to the skin using the Nanopatch™. In: Vaccine Technology V, Playa del Carmen, Mexico, (). 8-13 June 2014. Muller, David A. and Young, Paul R. (2013) The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker. Antiviral research, 98 2: 192-208. doi:10.1016/j.antiviral.2013.03.008 Simmons, G. S., Young, P. R., Hanger, J. J., Jones, K., Clarke, D., McKee, J. J. and Meers, J. (2012) Prevalence of koala retrovirus in geographically diverse populations in Australia. Australian Veterinary Journal, 90 10: 404-409. doi:10.1111/j.1751-0813.2012.00964.x Muller, David A., Frentiu, Francesca D., Rojas, Alejandra, Moriero, Luciano A., O'Neill, Scott L. and Young, Paul R. (2012) A portable approach for the surveillance of dengue virus-infected mosquitoes. Journal of Virological Methods, 183 1: 90-93. doi:10.1016/j.jviromet.2012.03.033 Muller, David A., Corrie, Simon R., Coffey, Jacob, Young, Paul R. and Kendall, Mark A. (2012) Surface modified microprojection arrays for the selective extraction of the dengue virus NS1 protein as a marker for disease. Analytical Chemistry, 84 7: 3262-3268. doi:10.1021/ac2034387 Muller, David A., Landsberg, Michael J., Bletchly, Cheryl, Rothnagel, Rosalba, Waddington, Lynne, Hankamer, Ben and Young, Paul R. (2012) Structure of the dengue virus glycoprotein non-structural protein 1 by electron microscopy and single-particle analysis. Journal of General Virology, 93 4: 771-779. doi:10.1099/vir.0.039321-0 Watterson, Daniel, Kobe, Bostjan and Young, Paul R. (2012) Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding. Journal of General Virology, 93 72-82. doi:10.1099/vir.0.037317-0 Fry, Scott R., Meyer, Michelle, Semple, Matthew G., Simmons, Cameron P., Sekaran, Shamala Devi, Huang, Johnny X., McElnea, Catriona, Huang, Chang-Yi, Valks, Andrea, Young, Paul R. and Cooper, Matthew A. (2011) The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach. PLoS Neglected Tropical Diseases, 5 6: e1199.1-e1199.8. doi:10.1371/journal.pntd.0001199 Duyen, Huynh T. L., Ngoc, Tran V., Ha, Do Thi, Hang, Vu T. T., Kieu, Nguyen T. T., Young, Paul R., Farrar, Jeremy J., Simmons, Cameron P., Wolbers, Marcel and Wills, Bridget A. (2011) Kinetics of plasma viremia and soluble non-structural protein 1 concentrations in dengue: Differential effects according to serotype and immune status. Journal of Infectious Diseases, 203 9: 1292-1300. doi:10.1093/infdis/jir014 Harrison, Rosemary S., Shepherd, Nicholas E., Hoang, Huy N., Ruiz-Goméz, Gloria, Hill, Timothy A., Driver, Russell W., Desai, Vishal S., Young, Paul R., Abbenante, Giovanni and Fairlie, David P. (2010) Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency. Proceedings of the National Academy of Sciences of the United States of America, 107 26: 11686-11691. doi:10.1073/pnas.1002498107 Kampmann, T., Yennamalli, R., Campbell, P., Stoermer, M. J., Fairlie, D. P., Kobe, B. and Young, P. R. (2009) In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses. Antiviral Research, 84 3: 234-241. doi:10.1016/j.antiviral.2009.09.007 Robin, Gautier, Chappell, Keith, Stoermer, Martin J., Hu, Shu-Hong, Young, Paul R., Fairlie, David P. and Martin, Jennifer L. (2009) Structure of West Nile virus NS3 protease: Ligand stabilization of the catalytic conformation. Journal of Molecular Biology, 385 5: 1568-1577. doi:10.1016/j.jmb.2008.11.026

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