个人简介

B.S., 1971, Univ. of Wisconsin-Eau Claire Ph.D., 1979, Iowa State Univ. NIH Postdoctoral Fellow, 1979-80, Princeton Univ. AwardOrganizationDivisionLevel CodeType CodeStart DateEnd Date CNS Distinguished Faculty AwardProfessionalHonors2013 ProfessorMichigan State UniversityProfessionalFaculty Position1999 FellowAmerican Association for the Advancement of ScienceProfessionalFellowship1998 ProfessorThe University of ChicagoProfessionalFaculty Position19921999 Associate ProfessorThe University of ChicagoProfessionalFaculty Position19861992 Young Scholar AwardEli LillyProfessionalHonors19861987 Assistant ProfessorThe University of ChicagoProfessionalFaculty Position1980 Postdoctoral FellowPrinceton University with Professor M.F. SemmelhackPostdoctoralEducation19791980 Ph.D.Iowa State UniversityGraduateDegree1979 Postdoctoral FellowshipNational Institutes of HealthPostdoctoralFellowship19791980 NIH Postdoctoral FellowNational Institutes of HealthPostdoctoralFellowship19791980 Research AssistantIowa State University with Professor T.J. BartonGraduateHonors19741979 Microwave radio repairUnited States Army Signal CorpsFort Monmouth, New JerseyGraduateEducation1972 Laboratory Technician1st United States Army Medical LaboratoryFort Meade, MarylandGraduateIndustrial19721974 Laboratory TechnicianSaint Agnes HospitalBaltimore, MarylandGraduateIndustrial19721974 Bachelor of ScienceUniversity of Wisconsin-Eau ClaireUndergraduateDegree1971 Research AssistantUniversity of Wisconsin-Eau Claire with Professor L.G. SchnackUndergraduateHonors19681971 MemberChemical Society (London)ProfessionalProfessional Activities MemberAmerican Chemical SocietyProfessionalProfessional Activities

研究领域

Organic Organometallic

(Research Description PDF - 1054 kb) Wulff Group Research is concentrated in the area of organic synthesis and catalysis. We are motivated by the pursuit of novel approaches in synthetic organic chemistry involving design and development of new asymmetric organocatalysis, organometallic chemistry, mechanistic studies and total synthesis of natural products. Research Field Highlights 1) New Enantioselective Organocatalysis 2) Fischer Carbene Chemistry 3) Mechanistic Investigations on Organocatalysis 4) Total Synthesis of Natural Products

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

J. Org. Chem. 2014,79, 10068. β-Amino Esters from the Reductive Ring Opening of Aziridine-2-carboxylates. Zhao, W.; Lu, Z.; Wulff, W. D. J. Am. Chem. Soc. 2014, 136, 13971-13974. Catalytic Asymmetric α-Iminol Rearrangement: New Chiral Platforms. Zhang, X.; Staples, R. J.; Rheingold, A. L.; Wulff, W. D. Chem. Eur. J, 2014, 20, 13894-13900. Catalytic Asymmetric Synthesis of Alkynyl Aziridines: Both Enantiomers of cis-Aziridines from One Enantiomer of the Catalyst. Guan, Y.; López-Alberca, M. P.; Lu, Z.; Zhang, Y.; Desai, A. A.; Patwardhan, A. P.; Dai, Y.; Vetticatt, M. J.; Wulff, W. D. Catal. Sci. Technol. 2014, 4, 4406. The iso-VAPOL ligand: synthesis, solid-state structure and its evaluation as a BOROX catalyst. Gupta, A. K.; Zhang, X.; Wulff, W. D. J. Am. Chem. Soc. 2014, 136, 10700-10707. Transition State Analysis of Enantioselective Br∅nsted Base Catalysis by Chiral Cyclopropenimines. Bandar, J. S.; Sauer, G. S.; Wulff, W. D.; Lambert, T. H.; Vetticatt, M. J. Angew. Chem. Int. Ed. 2014, 126, 9411-9415. Enantioselective Biomimetic Total Syntheses of Kuwanons I and J and Brosimones A and B. Han, J.; Li, X.; Guan, Y.; Zhao, W.; Wulff, W. D., Lei, X. Angew. Chem. Int. Ed. 2014, 53, 3436-3441. Three-Component Asymmetric Catalytic Ugi Reaction--Concinnity from Diversity by Substrate-Mediated Catalyst Assembly. Zhao, W.; Huang, L.; Guan, Y.; Wulff, W. D. Eur. J. Org. Chem. 2014, 7, 1386-1390. A General Synthesis of Sphinganines through Multicomponent Catalytic Asymmetric Aziridination. Mukherjee, M.; Zhou, Y.; Gupta, A. K.; Guan, Y.; Wulff, W. D. Chem. Eur. J, 2013,19, 15565-15571. Vaulted Biaryls in Catalysis: A Structure-Activity Relationship Guided Tour of the Immanent Domain of the VANOL Ligand. Guan, Y.; Ding, Z.; Wulff, W. D. Chem. Eur. J, 2013,19, 8261-8267. Synthesis of [m.n]Cyclophanes: Regiochemistry Transfer from Vinyl Halides to Cyclophanes via Fischer Carbene Complexes. Wang, H.; Predeus, A. V.; Wulff, W. D. J. Org. Chem. 2013, 78, 5142-5152. Isotope Effects and Mechanism of the Asymmetric BOROX Bronsted Acid Catalyzed Aziridination Reaction. Vetticatt, M. J.; Desai,A. A.; Wulff, W. D. Org. Lett. 2013, 15, 242-245. Total Synthesis of Sedium Alkaloids via Catalyst Controlled aza-Cope Rearrangement and Hydroformylation with Formaldehyde. Ren, H.; Wulff, W. D. Angew. Chem. Int. Ed. 2013, 52, 911-915. Rational Synthesis of All All-Homocalixarenes. Predeus, A. V.; Gopalsamuthiram, V.; Staples, R. J.; Wulff, W. D. Chem. Sci. 2013, 4, 622-628. Multifaceted Interception of 2-Chloro-2-Oxoacetic Anhydrides: A Catalytic Asymmetric Synthesis of beta-Lactams. Huang, L.; Zhao, W.; Staples, R. J.; Wulff, W. D. J. Org. Chem. 2012, 77, 7932-7944. BOROX Catalysis: Self-assembled amino-BOROX and imino-BOROX Intermediates in a Singular Five Component Catalyst Assembly/Catalytic Asymmetric Aziridination. Gupta, A. K.; Mukherjee, M.; Hu, G.; Wulff, W. D. Chem. Eur. J, 2012, 18, 5302-5313. Double Stereodifferentiation in the Catalytic Asymmetric Aziridination of Imines Prepared from α-Chiral Amine. Huang, L.; Zhang, Y.; Staples, R. J.; Huang, R. H.; Wulff, W. D. J. Am. Chem. Soc. 2012, 134, 1357-1362. Simultaneous Synthesis of both Rings of Chromenes via a Benzannulation/o-Quinone Methide Formation/Electrocyclization Cascade. Majumdar, N.; Korthals, K. A.; Wulff, W. D. Org. Process. Res. & Dev. 2011, 15, 1089-1107. Scalable Syntheses of the Vaulted Biaryl Ligands VAPOL and VANOL via the Cycloaddition/Electrocyclization Cascade. Ding, Z.; Osminski, W. E. G.; Ren, H.; Wulff, W. D. Org. Process. Res. & Dev. 2011, 15, 1108-1115. Practical Gram Scale Asymmetric Catalysis with Boroxinate Brønsted Acids Derived from the VAPOL and VANOL Ligands. Desai, A. A.; Ren, H.; Mukherjee, M.; Wulff, W. D. J. Am. Chem. Soc. 2011, 133, 8892-8895. Catalytic Asymmetric Synthesis of Tri-substituted Aziridines. Li Huang and William D. Wulff Org. Lett. 2011, 13, 5866-5869. Multicomponent Catalytic Asymmetric Aziridination of Aldehydes. Gupta, A. K.; Mukherjee, M.; Wulff, W. D. J. Am. Chem. Soc. 2011, 133, 5656-5659. Direct Catalytic Asymmetric Aminoallylation of Aldehydes – Synergism of Chiral- and Non-Chiral Brønsted Acids. Hong Ren and William D. Wulff J. Org. Chem. 2011, 76, 2913-2919. One Pot Synthesis of 2-Imidazolines via the Ring Expansion of Imidoyl Chlorides with Aziridines. Kuszpit, M. R.; Wulff, W. D.; Tepe, J. J. Chem. Asian J. 2011, 6, 2130-2146. A Succinct Synthesis of the Vaulted Biaryl Ligand VANOL via a Dienone-Phenol Rearrangement. Zhensheng Ding, Song Xue and William D. Wulff Organic Synthesis, 2011, 88, 224-237. Preparation of (2R,3R)-Ethyl 1-Benzhydr yl-3-(4-bromophenyl)aziridine-2-carboxylate by Catalytic Asymmetric Aziridination. Aman A. Desai, Roberto Morán-Ramallal and William D. Wulff Chem. Commun. 2010, 8213-8215. The Synthesis of Optically Active Calix[4]arenes with One or Three Substituents on the Methylene Bridges. Vijayagopal Gopalsamuthiram, Rui H. Huang and William D. Wulff J. Am. Chem. Soc., 2010, 132, 14669-14675. Substrate-Induced Covalent Assembly of a Chemzyme and Crystallographic Characterization of a Chemzyme-substrate Complex. Gang Hu, Anil K. Gupta, Rui H. Huang, Munmun Mukherjee and William D. Wulff Org. Lett. 2010, 12, 4908-4911. Trimethylsilyldiazomethane as a Versatile Stitching Agent for the Introduction of Aziridines into Functionalized Organic Moleculs. Hong Ren and William D. Wulff