Ortiz-Barrientos, Daniel - University of Queensland

研究领域

The ecological and genetic basis of speciation. As populations adapt to new environmental challenges they may become reproductively isolated from such other populations. The genetic changes associated with the evolution of reproductive isolation remain largely unknown, and therefore we have a limited understanding as to how ecology and genetics interact during the origin of new species. In the Ortiz-Barrientos lab we are tackling this problem by studying the early stages of speciation in the S. lautus species complex (sensu lato). Specifically, we are interested in identifying those genes responsibles for hybrid failure under field conditions, and in discovering their function within species. We use a combination of genomic, quantitative and classical genetics, together with reciprocal transplant experiments in our research. The genetics of adaptation. In his famous treatise on natural selection, Ronald A. Fisher argued that "The rate of increase in fitness of any organism at any time is equal to its genetic variance in fitness at that time". The genetic basis of traits contributing to fitness remains largely unresolved, particularly because some times many alleles of small effect control phenotypic variability, and because sometimes traits may evolve in step with other traits. These putative features of genetic architectures and trait evolution make the genetic study of adaptation difficult and impossible in most organisms. In our lab we are using mapping by selection of extreme tails to identify those genes responsible for ecotypic differences, and those traits responsible for fitness differences in the wild. Further, we are investigating the adaptive significance of genetic correlations during ecotypic divergence, and the relative contributions of additive vs. non-additive effects to fitness variation. The genetic basis of parallel evolution. Populations experiencing similar selective pressures may evolve similar traits. As they adapt to similar environments, populations may fix similar alleles, or they might reach a phenotypic solution via different biochemical and genetic routes. In the Ortiz-Barrientos lab we are investigating how maritime populations of S. lautus have repeatedly and independently adapted to contrasting habitats along the Australian coast. We are using population genomic approaches (e.g., using RAD tags) and mapping by selection experiments to identify those genomic regions responsible for the replicated evolution of tall and prostrate forms in S. lautus. We combine these results with the use of Nearly Isogenic Lines to test the adaptive significance of candidate genes under field conditions. Experimental evolution. Direct demonstration for the role of natural selection in the creation of new speciation is rare. Although microbial and unicellular eukaryotic organisms have provided insights as to how speciation occurs, there are very few examples in plants and animals as to how natural selection creates reproductive isolation. in the Ortiz-Barrientos lab we are exploring various strategies to deconstruct species and then to use natural selection to reconstruct them. Using specific quantitative genetic breeding designs together with QTL mapping we are tracking genetic changes that take place as adaptation proceeds and reproductive isolation revolves (e.g., the evolution of immigrant inviability and ecologically dependent postzygotic isolation). Results from these experiments will shed light on the connection between adaptation and speciation, and will help us understand how genetic architectures evolve

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Richards, Thomas J., Walter, Gregory M., McGuigan, Katrina and Ortiz-Barrientos, Daniel (2016) Divergent natural selection drives the evolution of extrinsic post zygotic isolation in an Australian wildflower. Evolution, . doi:10.1111/evo.12994. Richards, Thomas J. and Ortiz-Barrientos, Daniel (2016) Immigrant inviability produces a strong barrier to gene flow between parapatric ecotypes of Senecio lautus. Evolution, 70 6: 1239-1248. doi:10.1111/evo.12936 Ortiz-Barrientos, Daniel, Engelstaedter, Jan and Rieseberg, Loren H. (2016) Recombination rate evolution and the origin of species. Trends in Ecology and Evolution, 31 3: 226-236. doi:10.1016/j.tree.2015.12.016 Baack, Eric, Melo, Maria Clara, Rieseberg, Loreb H. and Ortiz-Barrientos, Daniel (2015) The origins of reproductive isolation in plants. New Phytologist, 207 4: 968-984. doi:10.1111/nph.13424 Matute, Daniel R. and Ortiz-Barrientos, Daniel (2014) Speciation: the strength of natural selection driving reinforcement. Current Biology, 24 19: R955-R957. doi:10.1016/j.cub.2014.08.033 Elliott, Alysha G., Delay, Christina, Liu, Huanle, Phua, Zaiyang, Rosengren, K. Johan, Benfield, Aurelie H., Panero, Jose L., Colgrave, Michelle L., Jayasena, Achala S., Dunse, Kerry M., Anderson, Marilyn A., Schilling, Edward E., Ortiz-Barrientos, Daniel, Craik, David J. and Mylne, Joshua S. (2014) Evolutionary origins of a bioactive peptide buried within preproalbumin. The Plant Cell, 26 3: 981-995. doi:10.1105/tpc.114.123620 Ortiz-Barrientos, Daniel and Baack, Eric J. (2014) Species integrity in trees. Molecular Ecology, 23 17: 4188-4191. doi:10.1111/mec.12867 Melo, Maria C., Grealy, Alicia, Brittain, Beth, Walter, Greg M. and Ortiz-Barrientos, Daniel (2014) Strong extrinsic reproductive isolation between parapatric populations of an Australian groundsel. New Phytologist, 203 1: 323-334. doi:10.1111/nph.12779 Roda, Federico, Liu, Huanle, Wilkinson, Melanie J., Walter, Gregory M., James, Maddie E., Bernal, Diana M., Melo, Maria C., Lowe, Andrew, Rieseberg, Loren H., Prentis, Peter and Ortiz-Barrientos, Daniel (2013) Convergence and divergence during the adaptation to similar environments by an Australian groundsel. Evolution, 67 9: 2515-2529. doi:10.1111/evo.12136 Roda, Federico, Ambrose, Luke, Walter, Gregory M., Liu, Huanle L., Schaul, Andrea, Lowe, Andrew, Pelser, Pieter B., Prentis, Peter, Rieseberg, Loren H. and Ortiz-Barrientos, Daniel (2013) Genomic evidence for the parallel evolution of coastal forms in the Senecio lautus complex. Molecular Ecology, 22 11: 2941-2952. doi:10.1111/mec.12311 Ortiz-Barrientos, Daniel (2013) The color genes of speciation in plants. Genetics, 194 1: 39-42. doi:10.1534/genetics.113.150466 Sambatti, Julianno B. M., Strasburg, Jared L., Ortiz-Barrientos, Daniel, Baack, Eric J. and Rieseberg, Loren H. (2012) Reconciling extremely strong barriers with high levels of gene exchange in annual sunflowers. Evolution, 66 5: 1459-1473. doi:10.1111/j.1558-5646.2011.01537.x David, Gwendolyn K., Condon, Catriona H., Bywater, Candice L., Ortiz-Barrientos, Daniel and Wilson, Robbie S. (2011) Receivers limit the prevalence of deception in humans: Evidence from diving behaviour in humans. PLoS One, 6 10: e26017-1-e26017-5. doi:10.1371/journal.pone.0026017 Prentis, Peter J., Woolfit, Megan, Thomas-Hall, Skye R., Ortiz-Barrientos, Daniel, Pavasovic, Ana, Lowe, Andrew J. and Schenk, Peer M. (2010) Massively parallel sequencing and analysis of expressed sequence tags in a successful invasive plant. Annals of Botany, 106 6: 1009-1017. doi:10.1093/aob/mcq201 Jasinska, A. J., Service, S., Jawaheer, D., DeYoung, J., Levinson, M., Zhang, Z., Kremeyer, B., Muller, H., Aldana, I., Garcia, J., Restrepo, G., Lopez, C., Palacio, C., Duque, C., Parra, M., Vega, J., Ortiz, D., Bedoya, G., Mathews, C., Davanzo, P., Fournier, E., Bejarano, J., Ramirez, M., Araya Ortiz, C., Araya, X., Molina, J., Sabatti, C., Reus, V., Ospina, J., Macaya, G., Ruiz-Linares, A. and Freimer, N. B. (2009) A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigrees. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 150 7: 998-1006. doi:10.1002/ajmg.b.30956 Ortiz-Barrientos, Daniel, Grealy, Alicia and Nosil, Patrik (2009) The genetics and ecology of reinforcement: Implications for the evolution of prezygotic isolation in sympatry and beyond. Annals of the New York Academy of Sciences, 1168 156-182. doi:10.1111/j.1749-6632.2009.04919.x Nosil, Patrik, Funk, Daniel J. and Ortiz-Barrientos, Daniel (2009) Divergent selection and heterogenous genomic divergence. Molecular Ecology, 18 3: 375-402. doi:10.1111/j.1365-294X.2008.03946.x Sambatti, J. B. M., Ortiz-Barrientos, D., Baack, E. J. and Rieseberg, L. H. (2008) Ecological selection maintains cytonuclear incompatibilities in hybridizing sunflowers. Ecology Letters, 11 10: 1082-1091. doi:10.1111/j.1461-0248.2008.01224.x Ortiz-Barrientos, Daniel and Kane, Nolan C. (2007) Meeting review: American Genetics Association Symposium on the genetics of speciation. Molecular Ecology, 16 14: 2852-2854. doi:10.1111/j.1365-294X.2007.03358.x Etges, William J., de Oliveira, Cassia Cardoso, Gragg, Erin, Ortiz-Barrientos, Daniel, Noor, Mohamed A. F. and Ritchie, Michael G. (2007) Genetics of incipient speciation in Drosophila mojavensis. I. Male courtship song, mating success, and genotype X environment interactions. Evolution, 61 5: 1106-1119. doi:10.1111/j.1558-5646.2007.00104.x