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研究领域

Stephen Simpson, together with David Raubenheimer, developed an integrative modelling framework for nutrition (the Geometric Framework), which was devised and tested using insects. This has since been applied to a wide range of organisms, from slime moulds to humans, and problems, from aquaculture and conservation biology to the dietary causes of human obesity and ageing. He has also revolutionised understanding of swarming in locusts, with research spanning neurochemical events within the brains of individual locusts to continental-scale mass migration. Stephen also leads the Nutritional Ecology and Physiology research group, which studies the neural, physiological, ecological and evolutionary bases of animal behaviour. The group's emphasis is 'bottom-up', in that we are especially concerned with the way in which lower-level processes lead to higher level outcomes. The approach focuses on the behaviour of individual organisms and involves an interplay between theory and experiment. Most of our experimental work is on insects, although recent work has examined fish, birds and mammals - including humans. Techniques employed include the quantitative analysis of behaviour, neurophysiology, metabolic and digestive physiology, mathematical modelling, computer simulations and laboratory selection experiments.

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Brazao, S., Chen, M., Murphy, R., Simpson, S., Coleman, R. (2016). A method for growing a monospecific epilithic cyanobacterial biofilm for use in marine ecological experiments. Journal of Experimental Marine Biology and Ecology, 480, 17-25. [More Information] Senior, A., Lihoreau, M., Charleston, M., Buhl, J., Raubenheimer, D., Simpson, S. (2016). Adaptive collective foraging in groups with conflicting nutritional needs. Royal Society Open Science, 3(4), 1-15. [More Information] Hewson-Hughes, A., Colyer, A., Simpson, S., Raubenheimer, D. (2016). Balancing macronutrient intake in a mammalian carnivore: disentangling the influences of flavour and nutrition. Royal Society Open Science, 3(6), 1-12. [More Information] Heflin, L., Raubenheimer, D., Simpson, S., Watts, S. (2016). Balancing macronutrient intake in cultured Lytechinus variegatus. Aquaculture, 450, 295-300. [More Information] Lihoreau, M., Clarke, I., Buhl, J., Sumpter, D., Simpson, S. (2016). Collective selection of food patches in Drosophila. The Journal of Experimental Biology, 219(5), 668-675. [More Information] Campbell, C., Raubenheimer, D., Badaloo, A., Gluckman, P., Martinez, C., Gosby, A., Simpson, S., Osmond, C., Boyne, M., Forrester, T. (2016). Developmental contributions to macronutrient selection: A randomized controlled trial in adult survivors of malnutrition. Evolution, Medicine and Public Health, 2016 (1), 158-169. [More Information] Cogger, V., Mohamad, M., Solon-Biet, S., Senior, A., Warren, A., O'Reilly, J., Tung, B., Svistounov, D., McMahon, A., Fraser, R., Raubenheimer, D., Holmes, A., Simpson, S., Le Couteur, D. (2016). Dietary Macronutrients and the Aging Liver Sinusoidal Endothelial Cell. American Journal of Physiology: Heart and Circulatory Physiology, 310(9), H1064-H1070. [More Information] Hawley, J., Simpson, S., Wilder, S. (2016). Flesh flies regulate the consumption of three macronutrients to maximize lifespan and egg production. Behavioral Ecology, 27(1), 245-251. [More Information] Hansen, M., Schaerf, T., Simpson, S., Ward, A. (2016). Group foraging decisions in nutritionally differentiated environments. Functional Ecology, in press. [More Information] Fernandez, M., Ordonana, J., Hartvigsen, J., Ferreira, M., Refshauge, K., Sanchez-Romera, J., De Barros Pinheiro, M., Simpson, S., Hopper, J., Ferreira, P. (2016). Is chronic low back pain associated with the prevalence of coronary heart disease when genetic susceptibility is considered? A co-twin control study of Spanish twins. PloS One, 11(5), 1-15. [More Information] Senior, A., Grueber, C., Machovsky-Capuska, G., Simpson, S., Raubenheimer, D. (2016). Macronutritional consequences of food generalism in an invasive mammal, the wild boar. Mammalian Biology, 81(5), 523-526. [More Information] Machovsky-Capuska, G., Coogan, S., Simpson, S., Raubenheimer, D. (2016). Motive for Killing: What Drives Prey Choice in Wild Predators? Ethology, 122, 703-711. [More Information] Machovsky-Capuska, G., Coogan, S., Simpson, S., Raubenheimer, D. (2016). Motive for Killing: What Drives Prey Choice in Wild Predators? Ethology, 122(9), 703-711. [More Information] Wilder, S., Raubenheimer, D., Simpson, S. (2016). Moving beyond body condition indices as an estimate of fitness in ecological and evolutionary studies. Functional Ecology, 30, 108-115. [More Information] Le Couteur, D., Solon-Biet, S., Wahl, D., Cogger, V., Willcox, B., Willcox, D., Raubenheimer, D., Simpson, S. (2016). New Horizons: Dietary protein, ageing and the Okinawan ratio. Age and Ageing, 45(4), 443-447. [More Information] Raubenheimer, D., Simpson, S. (2016). Nutritional Ecology and Human Health. Annual Review of Nutrition, 36, 603-626. [More Information] Raubenheimer, D., Simpson, S., Le Couteur, D., Solon-Biet, S., Coogan, S. (2016). Nutritional ecology and the evolution of aging. Experimental Gerontology, in press. [More Information] Wahl, D., Cogger, V., Solon-Biet, S., Waern, R., Gokarn, R., Pulpitel, T., de Cabo, R., Mattson, M., Raubenheimer, D., Simpson, S., Le Couteur, D. (2016). Nutritional strategies to optimise cognitive function in the aging brain. Ageing Research Reviews, in press. [More Information] Gosby, A., Lau, N., Tam, C., Iglesias, M., Morrison, C., Caterson, I., Brand-Miller, J., Conigrave, A., Raubenheimer, D., Simpson, S. (2016). Raised FGF-21 and Triglycerides Accompany Increased Energy Intake Driven by Protein Leverage in Lean, Healthy Individuals: A Randomised Trial. PloS One, 11(8), e0161003. [More Information] Dussutour, A., Poissonnier, L., Buhl, J., Simpson, S. (2016). Resistance to nutritional stress in ants: when being fat is advantageous. The Journal of Experimental Biology, 219(6), 824-833. [More Information]

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