Renfrew, Anna - University of Sydney

研究领域

My research focuses on using photoactive metal complexes for the selective delivery and release of anticancer agents. Bioinorganic medicinal chemistry Ruthenium-based anticancer agents Light-activated prodrugs Bioconjugation of tumour targeting groups and fluorescent tags

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

O'Neill, E., Kolanowski, J., Yin, G., Broadhouse, K., Grieve, S., Renfrew, A., Bonnitcha, P., New, E. (2016). Reversible magnetogenic cobalt complexes. RSC Advances, 6(36), 30021-30027. [More Information] Karaoun, N., Renfrew, A. (2015). A luminescent ruthenium(II) complex for light-triggered drug release and live cell imaging. Chemical Communications, 51(74), 14038-14041. [More Information] Renfrew, A., Bryce, N., Hambley, T. (2015). Cobalt(III) chaperone complexes of curcumin: Photoreduction, cellular accumulation and light-selective toxicity towards tumour cells. Chemistry - A European Journal, 21(43), 15224-15234. [More Information] Renfrew, A. (2014). Transition metal complexes with bioactive ligands: mechanisms for selective ligand release and applications for drug delivery. Metallomics, 6(8), 1324-1335. [More Information] Renfrew, A., Bryce, N., Hambley, T. (2013). Delivery and release of curcumin by a hypoxia-activated cobalt chaperone: a XANES and FLIM study. Chemical Science, 4(9), 3731-3739. [More Information] Yamamoto, N., Renfrew, A., Kim, B., Bryce, N., Hambley, T. (2012). Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex. Journal of Medicinal Chemistry, 55(24), 11013-11021. [More Information] Renfrew, A., Juillerat-Jeanneret, L., Dyson, P. (2011). Adding diversity to ruthenium(II)-arene anticancer (RAPTA) compounds via click chemistry: The influence of hydrophobic chains. Journal of Organometallic Chemistry, 696(3), 772-779. [More Information] Govender, P., Renfrew, A., Clavel, C., Dyson, P., Therrien, B., Smith, G. (2011). Antiproliferative activity of chelating N,O-and N,N-ruthenium(II) arene functionalised poly(propyleneimine) dendrimer scaffolds. Dalton Transactions, 40(5), 1158-1167. [More Information] Mattsson, J., Zava, O., Renfrew, A., Sei, Y., Yamaguchi, K., Dyson, P., Therrien, B. (2010). Drug delivery of lipophilic pyrenyl derivatives by encapsulation in a water soluble metalla-cage. Dalton Transactions, 39(35), 8248-8255. [More Information] Egger, A., Hartinger, C., Renfrew, A., Dyson, P. (2010). Metabolization of [Ru(eta(^6)-C(6)H(5)CF(3)(pta)Cl(2)]: a cytotoxic RAPTA-type complex with a strongly electron withdrawing arene ligand. Journal of Biological Inorganic Chemistry, 15(6), 919-927. [More Information] Schulz, J., Renfrew, A., Cisarova, I., Dyson, P., Stepnicka, P. (2010). Synthesis and anticancer activity of chalcogenide derivatives and platinum(II) and palladium(II) complexes derived from a polar ferrocene phosphanyl-carboxamide. Applied Organometallic Chemistry, 24(5), 392-397. [More Information] Suss-Fink, G., Khan, F., Juillerat-Jeanneret, L., Dyson, P., Renfrew, A. (2010). Synthesis and anticancer activity of long-chain isonicotinic ester ligand-containing arene ruthenium complexes and naoparticles. Journal of Cluster Science: including nanoclusters and nanoparticles, 21(3), 313-324. [More Information] Renfrew, A., Egger, A., Scopelliti, R., Hartinger, C., Dyson, P. (2010). Synthesis and characterisation of the water soluble bis-phosphine complex [Ru(eta(6)-cymene)(PPh(2)(o-C(6)H(4)O)-kappa(^2)-P,O)(pta)](^+) and an investigation of its cytotoxic effects (Invited publication). Academie des Sciences. Comptes Rendus. Chimie, 13(8-9), 1144-1150. [More Information] Renfrew, A., Scopelliti, R., Dyson, P. (2010). Use of perfluorinated phosphines to provide thermomorphic anticancer complexes for heat-based tumor targeting. Inorganic Chemistry, 49(5), 2239-2246. [More Information] Govender, P., Antonels, N., Mattsson, J., Renfrew, A., Dyson, P., Moss, J., Therrien, B., Smith, G. (2009). Anticancer activity of multinuclear arene ruthenium complexes coordinated to dendritic polypyridyl scaffolds. Journal of Organometallic Chemistry, 694(21), 3470-3476. [More Information] Auzias, M., Gueniat, J., Therrien, B., Suss-Fink, G., Renfrew, A., Dyson, P. (2009). Arene-ruthenium complexes with ferrocene-derived ligands: Synthesis and characterization of complexes of the type [Ru(η6-arene)(NC5H4CH2NHOC-C5H4FeC5H5)Cl2] and [Ru(η6-arene)(NC3H3N(CH2)2O2C-C5H4FeC5H5)Cl2]. Journal of Organometallic Chemistry, 694(6), 855-861. [More Information] Renfrew, A., Phillips, A., Egger, A., Hartinger, C., Bosquain, S., Nazarov, A., Keppler, B., Gonsalvi, L., Peruzzini, M., Dyson, P. (2009). Influence of Structural Variation on the Anticancer Activity of RAPTA-Type Complexes: ptn versus pta. Organometallics, 28(4), 1165-1172. [More Information] Renfrew, A. (2009). Ruthenium(II) arene compounds as versatile anticancer agents. Chimia, 63(4), 217-219. [More Information] Hartl, F., Renfrew, A., Lafolet, F., Mahabiersing, T., Calhorda, M., Chardon-Noblat, S., Haukka, M., Deronzier, A. (2009). Soluble redox-active polymetallic chains [{Ruo(CO)(L)(bpy)}m]n (bpy = 2,2'-bipyridine, L = PrCN, CI-; m = O, -1): Electrosynthesis and characterization. Inorganic Chemistry, 48(17), 8233-8244. [More Information] Mattsson, J., Govindaswamy, P., Renfrew, A., Dyson, P., Stepnicka, P., Suss-Fink, G., Therrien, B. (2009). Synthesis, molecular structure, and anticancer activity of cationic arene ruthenium metallarectangles. Organometallics, 28(15), 4350-4357. [More Information]