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研究领域

Pharmacokinetics and pharmacodynamics of drugs with particular interest in drug pharmacogenetics. Pharmacological and adverse effects of herbal medicines.

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Khanal, D., Kondyurin, A., Hau, H., Knowles, J., Levinson, O., Ramzan, I., Fu, D., Marcott, C., Chrzanowski, W. (2016). Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study. Analytical Chemistry, 88(15), 7530-7538. [More Information] Chua, H., Christensen, E., Hoestgaard-Jensen, K., Hartiadi, L., Ramzan, I., Jensen, A., Absalom, N., Chebib, M. (2016). Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism. PloS One, 11(6), 1-17. [More Information] Khanal, D., Dillon, E., Hau, H., Fu, D., Ramzan, I., Chrzanowski, W. (2015). Lorentz contact resonance spectroscopy for nanoscale characterisation of structural and mechanical properties of biological, dental and pharmaceutical materials. Journal of Materials Science: Materials in Medicine, 26(12), 1-10. [More Information] Rowe, A., Ramzan, I. (2012). Are mould hepatotoxins responsible for kava hepatotoxicity? Phytotherapy Research, 26(11), 1768-1770. [More Information] Fu, S., Rowe, A., Ramzan, I. (2012). Kavalactone metabolism in rat liver microsomes. Phytotherapy Research, 26(7), 1057-1061. [More Information] Fu, S., Rowe, A., Ramzan, I. (2012). Kavalactone Metabolism in the Isolated Perfused Rat Liver. Phytotherapy Research, 26(12), 1813-1816. [More Information] Zhang, L., Rowe, A., Braet, F., Ramzan, I. (2012). Macrophage depletion ameliorates kavalactone damage in the isolated perfused rat liver. The Journal of Toxicological Sciences, 37(2), 447-453. [More Information] Tan, A., Konczak, I., Ramzan, I., Sze, D. (2011). Antioxidant and cytoprotective activities of native Australian fruit polyphenols. Food Research International, 44(7), 2034-2040. [More Information] Rowe, A., Zhang, L., Hussain, A., Braet, F., Ramzan, I. (2011). Assessment and histological analysis of the IPRL technique for sequential in situ liver biopsy. Comparative Hepatology, 10, 7-1-7-7. [More Information] Rowe, A., Narlawar, R., Groundwater, P., Ramzan, I. (2011). Kavalactone Pharmacophores for Major Cellular Drug Targets. Mini - Reviews in Medicinal Chemistry, 11(1), 79-83. [More Information] Tang, J., Dunlop, R., Rowe, A., Rodgers, K., Ramzan, I. (2011). Kavalactones Yangonin and Methysticin Induce Apoptosis in Human Hepatocytes (HepG2) In Vitro. Phytotherapy Research, 25, 417-423. [More Information] Tan, A., Konczak, I., Sze, D., Ramzan, I. (2011). Molecular pathways for cancer chemoprevention by dietary phytochemicals. Nutrition and Cancer: an international journal, 63(4), 495-505. [More Information] Tan, A., Konczak, I., Ramzan, I., Sze, D. (2011). Native Australian Fruit Polyphenols Inhibit Cell Viability and Induce Apoptosis in Human Cancer Cell Lines. Nutrition and Cancer: an international journal, 63(3), 444-455. [More Information] Tan, A., Hou, D., Konczak, I., Tanigawa, S., Ramzan, I., Sze, D. (2011). Native Australian fruit polyphenols inhibit COX-2 and iNOS expression in LPS-activated murine macrophages. Food Research International, 44(7), 2362-2367. [More Information] Tan, A., Konczak, I., Ramzan, I., Zabaras, D., Sze, D. (2011). Potential Antioxidant, Antiinflammatory, and Proapoptotic Anticancer Activities of Kakadu Plum and Illawarra Plum Polyphenolic Fractions. Nutrition and Cancer: an international journal, 63(7), 1074-1084. [More Information] Rowe, A., Zhang, L., Ramzan, I. (2011). Toxicokinetics of Kava. Advances in Pharmacological Sciences, 2011 (Article ID 326724), 326724-1-326724-6. [More Information] Zhang, L., Rowe, A., Ramzan, I. (2010). Does inflammation play a role in kava hepatotoxicity? Phytotherapy Research, 25, 629-30. [More Information] Weekes, L., Ramzan, I. (2010). Generic medicines--how confident should we be? Pacific Health Dialog, 16(2), 109-111. [More Information] Ghassabian, S., Chetty, M., Tattam, B., Glen, J., Rahme, J., Stankovic, Z., Ramzan, I., Murray, M., McLachlan, A. (2010). The participation of cytochrome P450 3A4 in clozapine biotransformation is detected in people with schizophrenia by high-throughput in vivo phenotyping. Journal of Clinical Psychopharmacology, 30(5), 629-631. [More Information] Tan, A., Konczak, I., Sze, D., Ramzan, I. (2010). Towards the discovery of novel phytochemicals for disease prevention from native Australian plants: an ethnobotanical approach. Asia Pacific Journal of Clinical Nutrition, 19(3), 330-334. [More Information]

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