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Ahring, J., Bang, L., Jensen, M., Strobaek, D., Hartiadi, L., Collins, M., Absalom, N. (2016). A pharmacological assessment of agonists and modulators at alpha-4-beta-2-gamma-2 and alpha-4-beta-2-gamma GABAA receptors: The challenge in comparing apples with oranges. Pharmacological Research, 111, 563-576. [More Information]
Lee, H., Absalom, N., Hanrahan, J., van Nieuwenhuijzen, P., Ahring, J., Collins, M. (2016). A pharmacological characterization of GABA, THIP and DS2 at binary α4β3 and β3δ receptors: GABA activates β3δ receptors via the β3(+)δ(-) interface. Brain Research, 1644, 222-230. [More Information]
Hartiadi, L., Ahring, J., Chebib, M., Absalom, N. (2016). High and low GABA sensitivity alpha4beta2delta GABAA receptors are expressed in Xenopus laevis oocytes with divergent stoichiometries. Biochemical Pharmacology, 103, 98-108. [More Information]
Naffaa, M., Absalom, N., Solomon, V., Chebib, M., Hibbs, D., Hanrahan, J. (2016). Investigating the Role of Loop C Hydrophilic Residue 'T244' in the Binding Site of p1 GABAC Receptors via Site Mutation and Partial Agonism. PloS One, 11(5), 1-21. [More Information]
Chua, H., Christensen, E., Hoestgaard-Jensen, K., Hartiadi, L., Ramzan, I., Jensen, A., Absalom, N., Chebib, M. (2016). Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism. PloS One, 11(6), 1-17. [More Information]
Che Has, A., Absalom, N., van Nieuwenhuijzen, P., Clarkson, A., Ahring, J., Chebib, M. (2016). Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface. Scientific Reports, 6, 1-12. [More Information]
Carland, J., Yamamoto, I., Hanrahan, J., Abdel-Halim, H., Lewis, T., Absalom, N., Chebib, M. (2015). A Hydrophobic Area of the GABA p1 Receptor Containing Phenylalanine 124 Influences Both Receptor Activation and Deactivation. Journal of Molecular Neuroscience, 55(2), 305-313. [More Information]
Bowen, M., Peters, S., Absalom, N., Chebib, M., Neumann, I., McGregor, I. (2015). Oxytocin prevents ethanol actions at δ subunitcontaining GABAA receptors and attenuates ethanolinduced motor impairment in rats. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 112(10), 3104-3109. [More Information]
Absalom, N., Yamamoto, I., O'Hagan, D., Hunter, L., Collins, M. (2015). Probing the Mode of Neurotransmitter Binding to GABA Receptors Using Selectively Fluorinated GABA Analogues. Australian Journal of Chemistry, 68(1), 23-30. [More Information]
Chua, H., Absalom, N., Hanrahan, J., Viswas, R., Chebib, M. (2015). The Direct Actions of GABA, 2’-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABAA Receptors: Evidence for Receptors with Different Subunit Stoichiometries. PloS One, 10(10), 1-19. [More Information]
Indurthi Venkata, D., Pera, E., Kim, H., Chu, C., McLeod, M., McIntosh, J., Absalom, N., Chebib, M. (2014). Presence of multiple binding sites on Alpha9Alpha10 nAChR receptors alludes to stoichiometric-dependent action of the Alpha - conotoxin, Vc1.1. Biochemical Pharmacology, 89(1), 131-140. [More Information]
Absalom, N., Quek, G., Lewis, T., Qudah, T., von Arenstorff, I., Ambrus, J., Harpsøe, K., Karim, N., Balle, T., McLeod, M., Chebib, M. (2013). Covalent trapping of methyllycaconitine at the alpha4-alpha4 interface of the apha4beta2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed. Journal of Biological Chemistry, 288(37), 26521-26532. [More Information]
Karim, N., Wellendorph, P., Absalom, N., Johnston, G., Hanrahan, J., Chebib, M. (2013). Potency of gaba at human recombinant gaba alpha receptors expressed in xenopus oocytes: a mini review. Amino Acids, 44(4), 1139-1149. [More Information]
Absalom, N., Eghorn, L., Villumsen, I., Karim, N., Bay, T., Olsen, J., Knudsen, G., Brauner-Osborne, H., Frølund, B., Clausen, R., Chebib, M., et al (2012). (alpha)4(beta)(delta) GABAA receptors are high-affinity targets for gamma-hydroxybutyric acid (GHB). Proceedings of the National Academy of Sciences of the United States of America (PNAS), 109(33), 13404-13409. [More Information]
Ambrus, J., Halliday, J., Kanizaj, N., Absalom, N., Harpsøe, K., Balle, T., Chebib, M., McLeod, M. (2012). Covalent attachment of antagonists to the (alpha)7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides. Chemical Communications, 48(53), 6699-6701. [More Information]
Yamamoto, I., Absalom, N., Carland, J., Doddareddy, M., Gavande, N., Johnston, G., Hanrahan, J., Chebib, M. (2012). Differentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABAC rho1 Receptors. ACS Chemical Neuroscience, 3(9), 665-673. [More Information]
Karim, N., Wellendorph, P., Absalom, N., Bang, L., Jensen, M., Hansen, M., Lee, H., Johnston, G., Hanrahan, J., Chebib, M. (2012). Low nanomolar GABA effects at extrasynaptic a4b1/b3d GABAA receptor subtypes indicate a different binding mode for GABA at these receptors. Biochemical Pharmacology, 84(4), 549-557. [More Information]
Yamamoto, I., Carland, J., Locock, K., Gavande, N., Absalom, N., Hanrahan, J., Allan, R., Johnston, G., Chebib, M. (2012). Structurally Diverse GABA Antagonists Interact Differently with Open and Closed Conformational States of the p1 Receptor. ACS Chemical Neuroscience, 3(4), 293-301. [More Information]
Yow, T., Pera, E., Absalom, N., Heblinski, M., Johnston, G., Hanrahan, J., Chebib, M. (2011). Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q. British Journal of Pharmacology, 163(5), 1017-1033. [More Information]
Quek, G., Lin, D., Halliday, J., Absalom, N., Ambrus, J., Thompson, A., Lochner, M., Lummis, S., McLeod, M., Chebib, M. (2010). Identifying the Binding Site of Novel Methyllycaconitine (MLA) Analogs at α4β2 Nicotinic Acetylcholine Receptors. ACS Chemical Neuroscience, 1(12), 796-809. [More Information]