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研究领域

Professor Britton is the Head of the Discipline of Infectious Diseases & Immunology and the Mycobacterial Research Program in the Centenary Institute of Cancer Medicine & Cell Biology, where he studies the immunological control of tuberculosis and new vaccine strategies to control this major human infection.

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Ritz, N., Casalaz, D., Donath, S., Tebruegge, M., Dutta, B., Connell, T., Robins-Browne, R., Britton, W., Hanekom, W., Curtis, N. (2016). Comparable CD4 and CD8 T cell responses and cytokine release after at birth and delayed BCG immunisation in infants born in Australia. Vaccine, 34(35), 4132-4139. [More Information] Parumasivam, T., Chang, R., Abdelghany, S., Ye, T., Britton, W., Chan, K. (2016). Dry powder inhalable formulations for anti-tubercular therapy. Advanced Drug Delivery Reviews, 102, 83-101. [More Information] Stifter, S., Bhattacharyya, N., Pillay, R., Florido, M., Triccas, J., Britton, W., Feng, C. (2016). Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation. PLoS Pathogens, 12(1), 1-20. [More Information] Parumasivam, T., Chan, J., Pang, A., Quan, D., Triccas, J., Britton, W., Chan, K. (2016). In Vitro Evaluation of Inhalable Verapamil-Rifapentine Particles for Tuberculosis Therapy. Molecular Pharmaceutics, 13(3), 979-989. [More Information] Parumasivam, T., Chan, J., Pang, A., Quan, D., Triccas, J., Britton, W., Chan, K. (2016). In vitro evaluation of novel inhalable dry powders consisting of thioridazine and rifapentine for rapid tuberculosis treatment. European Journal of Pharmaceutics and Biopharmaceutics, 107, 205-214. [More Information] Pinto (Pinto-Nadanachandran), R., Nambiar, J., Leotta, L., Counoupas, C., Britton, W., Triccas, J. (2016). Influence of phthiocerol dimycocerosate on CD4�?� T cell priming and persistence during Mycobacterium tuberculosis infection. Tuberculosis, 99, 25-30. [More Information] Leung, S., Parumasivam, T., Gao, F., Carrigy, N., Vehring, R., Finlay, W., Morales, S., Britton, W., Kutter, E., Chan, K. (2016). Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections. Pharmaceutical Research, 33(6), 1486-1496. [More Information] Parumasivam, T., Leung, S., Quan, D., Triccas, J., Britton, W., Chan, K. (2016). Rifapentine-loaded PLGA microparticles for tuberculosis inhaled therapy: Preparation and in vitro aerosol characterization. European Journal of Pharmaceutical Sciences, 88, 1-11. [More Information] Giltrap, A., Dowman, L., Nagalingam, G., Ochoa, J., Linington, R., Britton, W., Payne, R. (2016). Total synthesis of teixobactin. Organic Letters, 18(11), 2788-2791. [More Information] Fox, G., Loan, L., Viet Nhung, N., Loi, N., Sy, D., Britton, W., Marks, G. (2015). Barriers to adherence with tuberculosis contact investigation in six provinces of Vietnam: a nested case-control study. BMC Infectious Diseases, 15(1), 1-8. [More Information] Florido, M., Pillay, R., Gillis, C., Xia, Y., Turner, S., Triccas, J., Stambas, J., Britton, W. (2015). Epitope-specific CD4(+) , but not CD8(+) , T-cell responses induced by recombinant influenza A viruses protect against Mycobacterium tuberculosis infection. European Journal of Immunology, 45(3), 780-793. [More Information] Barry, S., Chan, B., Ellis, M., Yang, Y., Plit, M., Guan, G., Wang, X., Britton, W., Saunders, B. (2015). Identification of miR-93 as a suitable miR for normalizing miRNA in plasma of tuberculosis patients. Journal of Cellular and Molecular Medicine, 19(7), 1606-1613. [More Information] Hare, N., Chan, B., Chan, E., Kaufman (nee Alexander), K., Britton, W., Saunders, B. (2015). Microparticles released from Mycobacterium tuberculosis-infected human macrophages contain increased levels of the type I interferon inducible proteins including ISG15. Proteomics, 15(17), 3020-3029. [More Information] Chan, J., Tyne, A., Pang, A., McLachlan, A., Perera, V., Chan, J., Britton, W., Chan, K., Duke, C., Young, P., Traini, D. (2015). Murine pharmacokinetics of rifapentine delivered as an inhalable dry powder. International Journal of Antimicrobial Agents, 45(3), 319-323. [More Information] Chan, J., Duke, C., Ong, H., Chan, J., Tyne, A., Chan, H., Britton, W., Young, P., Traini, D. (2014). A Novel Inhalable Form of Rifapentine. Journal of Pharmaceutical Sciences, 103(5), 1141-1421. [More Information] Chan, J., Tyne, A., Pang, A., Chan, H., Young, P., Britton, W., Duke, C., Traini, D. (2014). A Rifapentine-Containing Inhaled Triple Antibiotic Formulation for Rapid Treatment of Tubercular Infection. Pharmaceutical Research, 31(5), 1239-1253. [More Information] Weber-Chrysochoou, C., Crisafulli, D., Kemp, A., Britton, W., Marks, G., Investigators, C. (2014). Allergen-specific IL-5 responses in early childhood predict asthma at age eight. PloS One, 9(5), 1-7. [More Information] Majumdar, S., Marais, B., Denholm, J., Britton, W. (2014). Drug-resistant tuberculosis: collaborative regional leadership required. Medical Journal of Australia, 200(5), 241-242. [More Information] Fox, G., Sy, D., Viet Nhung, N., Yu, B., Ellis, M., Hung, N., Cuong, N., Lien, L., Marks, G., Saunders, B., Britton, W. (2014). Polymorphisms of SP110 Are Associated with both Pulmonary and Extra-Pulmonary Tuberculosis among the Vietnamese. PloS One, 9(7), e99496. [More Information] Gunaratnam, P., Britton, W., Hofmeyr, A. (2013). Bug breakfast in the bulletin: Leprosy. NSW Public Health Bulletin, 24(1), 50-50.

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