Hegedus, Elizabeth - University of Sydney - Discipline of Biomedical Science

研究领域

The discovery of penicillin by Sir Alexander Fleming heralded the beginning of the Antibiotic Era, offering hope for the treatment of many infectious diseases. However, within just a few decades, the emergence of "superbugs" with resistance to multiple classes of antimicrobial agents threatens to bring it to an abrupt end. The widespread use of antimicrobial agents is one of the main drivers of the development of antimicrobial resistance in human pathogens. Antimicrobials are used not only in human and veterinary medicine, but also in animal husbandry and other agricultural activities and are increasingly being used in surface wipes and other products used for domestic cleaning and personal hygiene. I am currently investigating the emergence and epidemiology of microbes that are resistant to multiple antimicrobial drugs, in particular hospital and community acquired methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.

近期论文

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Ritchie, H., Oakes, D., Hung, T., Hegedus, E., Sood, S., Webster, W. (2015). The Effect of Dofetilide on the Heart Rate of GD11 and GD13 Rat Embryos, in vivo, Using Ultrasound. Birth Defects Research (Part B), 104(5), 196-203. [More Information] Wu, M., Giersch, T., McKay, S., Schofield, P., Skylas, D., Cornish, G., Hegedus, E., Chin, J. (2012). A novel hardness-related and starch granule-associated protein marker in wheat: LMW-GS-'S'. Journal of Cereal Science, 55(2), 153-159. [More Information] Wu, M., McKay, S., Howes, N., Chin, J., Hegedus, E. (2012). Identification of novel serpin isoforms and serpin polymorphisms among Australian wheat cultivars. Journal of Cereal Science, 55(2), 202-209. [More Information] Wu, M., McKay, S., Hegedus, E., Chin, J. (2012). Proteolytic extraction enhances specific detection of the novel 'S'-type low molecular weight glutenin subunit in wheat by monoclonal antibody. Journal of Cereal Science, 55(1), 53-60. [More Information] Wu, M., McKay, S., Howes, N., Hegedus, E., Chin, J. (2011). Polymorphism and pedigree analysis of b-amylase isozymes in Australian wheat. Journal of Cereal Science, 53, 362-370. [More Information] Bailey (nee Patterson), J., Chandrasekara, A., Bao, B., Hegedus, E., Caterson, I., Denyer, G., Turner, B., Mullbacher, A., Chin, J. (2006). Prebiotic supplementation with resistant starch alters health indices associated with metabolic changes and intestinal dysbiosis. International Journal of Probiotics and Prebiotics, 1(3 & 4), 181-192. Ramadhan, A., Hegedus, E. (2005). Biofilm formation and esp gene carriage in enterococci. Journal of Clinical Pathology, 58(7), 685-686. [More Information] Bailey (nee Patterson), J., Chapman, T., Hegedus, E., Barchia, I., Chin, J. (2005). Selected culturable enteric bacterial populations are modified by diet acidification and the growth promotant Tylosin. Letters in Applied Microbiology, 41, 119-124. [More Information] Ramadhan, A., Hegedus, E. (2005). Survivability of vancomycin resistant enterococci and fitness cost of vancomycin resistance acquisition. Journal of Clinical Pathology, 58(7), 744-746. [More Information]