Holsinger, Damian - University of Sydney - Discipline of Biomedical Science

研究领域

Research interests surround the understanding of mechanisms by which complex neurological disorders (with a special interest in Alzheimer's dsiease) arise and methods of treating these diseases.

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Rollo, J., Banihashemi, N., Vafaee, F., Crawford, J., Kuncic, Z., Holsinger, D. (2016). Unraveling the mechanistic complexity of Alzheimer's disease through systems biology. Alzheimer's and Dementia, 12(6), 708-718. [More Information] Rollo, J., Banihashemi, N., Vafaee, F., Crawford, J., Kuncic, Z., Holsinger, D. (2016). Unraveling the mechanistic complexity of Alzheimer’s disease through systems biology. Alzheimer's and Dementia, 12(6), 708-718. [More Information] Holsinger, D. (2015). Translation of low-risk dementia-associated interventions into practice- a call to action. Healthy Aging Research, 4(30), 1-9. [More Information] Thompson, G., Ireland, T., Larkin, X., Arnold, J., Holsinger, D. (2014). A Novel Segmentation-Based Algorithm for the Quantification of Magnified Cells. Journal Of Cellular Biochemistry, 115, 1849-1854. [More Information] Buljan, V., Holsinger, D., Hambly, B., Kanellis, V., Matar, E., Larkin, X., Liu, G., Bohorquez-Florez, J., Banati, R. (2014). Intrinsic synergistic-topological mechanism versus synergistic-topological matrix in microtubule self-organization. EPJ Nonlinear Biomedical Physics, 2, 1-28. Sajjan, S., Holsinger, D., Fok, S., Ebrahimkhani, S., Rollo, J., Banati, R., Graeber, M. (2014). Up-regulation of matrix metallopeptidase 12 in motor neurons undergoing synaptic stripping. Neuroscience, 274, 331-340. [More Information] Buljan, V., Holsinger, D., Hambly, B., Banati, R., Ivanova, E. (2013). Intrinsic microtubule GTP-cap dynamics in semi-confined systems: kinetochore-microtubule interface. Journal of Biological Physics, 39(1), 81-98. [More Information] Kosaraju, J., Gali, C., Khatwal, R., Dubala, A., Chinni, S., Holsinger, D., Madhunapantula, V., Nataraj, S., Basavan, D. (2013). Saxagliptin: A dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease. Neuropharmacology, 72, 291-300. [More Information] Buljan, V., Holsinger, D., Brown, D., Bohorquez-Florez, J., Hambly, B., Delikatny, E., Ivanova, E., Banati, R. (2013). Spinodal decomposition and the emergence of dissipative transient periodic spatio-temporal patterns in acentrosomal microtubule multitudes of different morphology. Chaos, 23(2), 1-16. [More Information] Holsinger, D., Goense, N., Bohorquez-Florez, J., Strappe, P. (2013). Splice variants of the Alzheimer’s disease beta-secretase, BACE1. Neurogenetics, 14(1), 1-9. [More Information] Li, W., Holsinger, D., Kruse, C., Flugel, A., Graeber, M. (2013). The Potential for Genetically Altered Microglia to Influence Glioma Treatment. CNS & Neurological Disorders - Drug Targets, 12(6), 750-762. [More Information] Holsinger, D., Brown, R., Richmond, R., Kay-Lambkin, F., Kirby, A., Chan, D. (2012). Prevalence of the long-allele genotype of the serotonin transporter-linked gene in female centenarians. Journal of the American Geriatrics Society, 60(9), 1786-1788. [More Information] George, A., Gordon, L., Beissbarth, T., Koukoulas, I., Holsinger, D., Perreau, V., Cappai, R., Tan, S., Masters, C., Scott, H., et al (2010). A Serial Analysis of Gene Expression Profile of the Alzheimer's Disease Tg2576 Mouse Model. Neurotoxicity Research, 17, 360-379. [More Information] Kassiou, M., Banati, R., Holsinger, D., Meikle, S. (2009). Challenges in molecular imaging of Parkinson's disease: A brief overview. Brain Research Bulletin, 78(2-3), 105-108. [More Information] Einfeld, S., Goetz, J., Holsinger, D. (2008). Pathogenetic mechanisms in Down Syndrome. Journal of Intellectual Disability Research, 52(10), 813-813. [More Information] Einfeld, S., Goetz, J., Holsinger, R. (2008). Two novel genes associated with Down’s syndrome. Journal of Intellectual Disability Research, 52(10), 813. White, A., Du, T., Laughton, K., Volitakis, I., Sharples, R., Hoke, D., Holsinger, R., Evin, G., Cherny, R., Hill, A., et al (2006). Clioquinol induces metal-dependent degradation of the Alzheimer's disease amyloid beta peptide by up-regulation of matrix metalloproteases. Journal of Neurochemistry, 98(90). Holsinger, D., Lee, J., Boyd, A., Masters, C., Collins, S. (2006). CSF BACE1 activity is increased in CJD and Alzheimer disease other dementias. Neurology, 67(4), 710-712. [More Information] George, A., Holsinger, D., McLean, C., Tan, S., Scott, H., Cardamone, T., Cappai, R., Masters, C., Li, Q. (2006). Decreased phosphatidylethanolamine binding protein expression correlates with Aβ accumulation in the Tg2576 mouse model of Alzheimer's disease. Neurobiology of Aging, 27(4), 614-623. [More Information] White, A., Du, T., Laughton, K., Volitakis, I., Sharples, R., Xilinas, M., Hoke, D., Holsinger, D., Evin, G., Cherny, R., et al (2006). Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity. Journal of Biological Chemistry, 281(26), 17670-17680. [More Information]