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研究领域

Dr Helen Ritchie is a developmental toxicologist with a special interest in the effects of vitamin A, herbal medicine and cardiovascular medicines on the developing embryo and fetus.

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Ritchie, H., Oakes, D., Hung, T., Hegedus, E., Sood, S., Webster, W. (2015). The Effect of Dofetilide on the Heart Rate of GD11 and GD13 Rat Embryos, in vivo, Using Ultrasound. Birth Defects Research (Part B), 104(5), 196-203. [More Information] Ritchie, H., Svensson, C., Nilsson, M., Webster, W. (2014). A comparison of drug-induced cardiotoxicity in rat embryos cultured in human serum or protein free media. Journal of Pharmacological and Toxicological Methods, 70(3), 276-282. [More Information] Webster, W., Nilsson, M., Ritchie, H. (2014). Therapeutic Drugs that Slow the Heart Rate of Early Rat Embryos. Is there a Risk for the Human? Current Pharmaceutical Design, 20(34), 5364-5376. Nilsson, M., Ritchie, H., Webster, W. (2013). The effect on rat embryonic heart rate of Na+, K+, and Ca2+ channel blockers, and the human teratogen phenytoin, changes with gestational age. Birth Defects Research (Part B), 98(5), 416-427. [More Information] Ritchie, H., Ababneh, D., Oakes, D., Power, C., Webster, W. (2013). The teratogenic effect of dofetilide during rat limb development and association with drug-induced bradycardia and hypoxia in the embryo. Birth Defects Research (Part B), 98(2), 144-153. [More Information] Ababneh, D., Ritchie, H., Webster, W. (2012). Antidepressants Cause Bradycardia and Heart Block in GD 13 Rat Embryos In Vitro. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 95(2), 184-193. [More Information] Gunnstrom, M., Ababneh, D., Webster, W., Oakes, D., Ritchie, H. (2012). Antipsychotic drugs cause bradycardia in GD 13 rat embryos in vitro. Reproductive Toxicology, 34(3), 443-450. [More Information] Abela, D., Ritchie, H., Ababneh, D., Gavin, C., Nilsson, M., Khan, M., Carlsson, K., Webster, W. (2010). The effect of drugs with ion channel-blocking activity on the early embryonic rat heart. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 89(5), 429-440. [More Information] Oakes, D., Ritchie, H., Woodman, P., Narup, E., Moscova, M., Picker, K., Webster, W. (2009). Genotoxicity studies of a desealant solvent mixture, SR-51. Toxicology and Industrial Health: An International Journal, 25(1), 5-13. [More Information] Yao, M., Ritchie, H., Brown-Woodman, P. (2008). A reproductive screening test of hawthorn. Journal of Ethnopharmacology, 118, 127-132. [More Information] Warner, R., Ritchie, H., Woodman, P., Oakes, D., Pourghasem, M. (2008). The effect of prenatal exposure to a repeat high dose of toluene in the fetal rat. Reproductive Toxicology, 26, 267-272. [More Information] Yao, M., Ritchie, H., Woodman, P. (2007). A developmental toxicity-screening test of valerian. Journal of Ethnopharmacology, 113(2), 204-209. [More Information] Yao, M., Ritchie, H., Woodman, P. (2006). A reproductive screening test of feverfew. Is a full reproductive study warranted? Reproductive Toxicology, 22(4), 688-693. [More Information] Yao, M., Ritchie, H., Woodman, P. (2005). A reproductive screening test of goldenseal. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 74(5), 399-404. [More Information] Woodman, P., Ritchie, H., Korabelnikoff, A., Emmanuel, C. (2004). Replacement Of Ether With Alternate Volatile Anesthetics For Collection Of Rat Serum Used In Embryo Culture. Toxicology in Vitro, 18(5), 719-724. Ritchie, H., Woodman, P., Korabelnikoff, A. (2003). Effect of Co-Administration of Retinoids on Rat Embryo Development In Vitro. Birth Defects Research. Part A: Clinical and Molecular Teratology, 67(6), 444-451. [More Information] Boswell-Ruys, C., Ritchie, H., Woodman, P. (2003). Preliminary screening study of reproductive outcomes after exposure to yarrow in the pregnant rat. Birth Defects Research. Part B: Developmental and Reproductive Toxicology, 68(5), 416-420. [More Information] Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2002). A Study of the Potential for a Herbicide Formulation Containing 2,4-D and Picloram to Cause Male-Mediated Developmental Toxicity in Rats. Toxicological Sciences, 68(1), 200-206. Oakes, D., Webster, W., Woodman, P., Ritchie, H. (2002). Testicular changes induced by chronic exposure to the herbicide formulation, Tordon 75D(R) (2,4-dichlorophenoxyacetic acid and picloram)in rats. Reproductive Toxicology, 16(3), 281-289.

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