吕聪 - 中国农业大学 - 营养与健康系（营养与健康研究院）

个人简介

2020.11-至今：中国农业大学，优秀人才引进，副教授 2018.7-2020.10：中国农业大学，博士后 2013.9-2018.6：中国农业大学，理学博士 2009.6-2013.6：河北农业大学，工学学士课题项目国家自然科学基金青年科学基金项目，82000498，间充质Islr在结肠炎中调控上皮再生的功能及机制究，2021.1.1-2023.12.31，30万元，在研，主持中国农业大学基本科研业务费专项资金项目，2022TC094，探究肠道干细胞抵抗辐射并驱动损伤修复的新机制，2022.1.1-2022.10.30，12万元，在研，主持博士后创新人才计划，BX20180365，探究microRNA在小肠干细胞和肠道健康中的功能和调控机制，2018.09.01-2020.09.01，60万元，已结题，主持博士后基金面上项目，2018M641534，探究Numb和Numbl基因在乳腺癌转移过程中的作用机制，2019.1.1-2020.12.31，5万元，已结题，主持

研究领域

肠道干细胞的功能与调控机制研究肠道微环境与肠道健康

近期论文

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Min Deng#; Christian F. Guerrero-Juarez#; Xiaole Sheng; Jiuzhi Xu; Xi Wu; Kai Yao; Mengzhen Li; Xu Yang; Guilin Li; Jintao Xiao; Xiaowei Liu; Kaichun Wu; Fazheng Ren; Qing Nie; Maksim V. Plikus; Zhengquan Yu* and Cong Lv*;Lepr+ mesenchymal cells sense diet to modulate intestinal stem/progenitor cells via Leptin-Igf1 axis, Cell Research, 2022. Ruiqi Liu#; Huan Hu; Melissa McNeil; Jiuzhi Xu; Xueyun Bi; Pengbo Lou; Christian F. Guerrero-Juarez; Xing Dai; Maksim V. Plikus; Jianwei Shuai*; Zhengquan Yu*; Cong Lv*;Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation, iScience, 2022, 25(3):103982. Jianyang Wang#; Linkuo Shang#; Jiahui Zhang; Zhengquan Yu; Jiaqiang Huang*; Jing Jin*; Cong Lv*; Nfatc1+ colonic stem cells contribute to regeneration upon colitis, Journal of Gastroenterology and Hepatology, 2022, 37(4):734-740. Min Deng; Xi Wu; Xiaoyue Duan; Jiuzhi Xu; Xu Yang; Xiaole Sheng; Pengbo Lou; Chunlei Shao; Cong Lv* and Zhengquan Yu *; Lactobacillus paracasei L9 improves colitis by expanding butyrate-producing bacteria that inhibit the IL-6/STAT3 signaling pathway; Food & Function, 2021, 12(21):10700-10713. Chunlei Shao; Pengbo Lou; Ruiqi Liu; Xueyun Bi; Guilin Li; Xu Yang; Xiaole Sheng; Jiuzhi Xu; Cong Lv*; Zhengquan Yu*; Hormone-Responsive BMP Signaling. Expands Myoepithelial Cell Lineages and Prevents Alveolar Precocity in Mammary Gland, Frontiers in Cell and Developmental Biology, 2021, 9:691050. Cong Lv#; Fengyin Li#; Xiang Li#; Yuhua Tian#; Yue Zhang; Xiaole Sheng; Yongli Song; Qingyong Meng; Shukai Yuan; Liming Luan; Thomas Andl; Xu Feng; Baowei Jiao; Mingang Xu; Maksim V Plikus; Xing Dai; Christopher Lengner; Wei Cui; Fazheng Ren; Jianwei Shuai; Sarah E Millar; Zhengquan Yu*; MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists, Nature Communications, 2017, 8(1). Xiaole Sheng#; Ziguang Lin#; Cong Lv#; Chunlei Shao; Xueyun Bi; Min Deng; Jiuzhi Xu; Christian F Guerrero-Juarez; Mengzhen Li; Xi Wu; Ran Zhao; Xu Yang; Guilin Li; Xiaowei Liu; Qingyu Wang; Qing Nie; Wei Cui; Shan Gao; Hongquan Zhang; Zhihua Liu; Yingzi Cong; Maksim V Plikus; Christopher J Lengner; Bogi Andersen; Fazheng Ren*; Zhengquan Yu*; Cycling Stem Cells Are Radioresistant and Regenerate the Intestine, Cell Reports, 2020, 32(4):107952. Yuhua Tian#; Xianghui Ma#; Cong Lv#; Xiaole Sheng; Xiang Li; Ran Zhao; Yongli Song; Thomas Andl; Maksim V Plikus; Jinyue Sun; Fazheng Ren; Jianwei Shuai; Christopher J Lengner; Wei Cui; Zhengquan Yu*; Stress responsive miR-31 is a major modulator of mouse intestinal stem cells during regeneration and tumorigenesis, eLife, 2017, 6(e29538).