罗俊杰 - 中国农业大学 - 营养与健康系（营养与健康研究院）

个人简介

2020.06-至今：中国农业大学，优秀人才引进，副教授 2016.07-2020.06：北京食品营养与人类健康创新中心，岗位科学家 2013.07-2016.06：北京大学，博士后 2008.09-2013.06：中国农业大学，理学博士 2004.09-2008.06：中国农业大学，工学学士课题项目国家自然科学基金面上项目：哺乳动物中miRNA抑制作用的分子机制及调控网络的演化规律 2016-2019 参与国家自然科学基金重大研究计划：果蝇转座元件和piRNA之间的基因组冲突及对杂交不育的影响2015-2017 参与国家转基因生物新品种培育重大专项：高产优质肉牛新品种培育2013-2015 参与国家转基因生物新品种培育科技重大专项：高品质转基因奶牛新品种培育 2011-2015 参与国家高技术研究发展计划(863计划)：朊蛋白及β-乳球蛋白基因敲除奶牛的研制 2008-2010 参与

研究领域

线粒体与心血管疾病、代谢综合征、癌症以及衰老等线粒体DNA突变与基因编辑糖脂代谢稳态调控

近期论文

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Yu S#, Luo J#, Song Z, Ding F, Dai Y, Li N*. Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle. Cell research 2011;21(11):1638-40. doi: 10.1038/cr.2011.153. Luo S#, He F#, Luo J#, Dou S#, Wang Y, Guo A, Lu J*. Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response. Nucleic acids research 2018;46(10):5250-68. doi: 10.1093/nar/gky189. Wang Y#, Wang X#, Long Q#, *, Liu Y, Yin T, Sirota I, Ren F, Gu Z*, Luo J*. Reducing embryonic mtDNA copy number alters epigenetic profile of key hepatic lipolytic genes and causes abnormal lipid accumulation in adult mice. The FEBS journal 2021. doi: 10.1111/febs.16121. Wang X#, An P#, Gu Z, Luo Y* and Luo J*. Mitochondrial Metal Ion Transport in Cell Metabolism and Disease. International journal of molecular sciences 2021;22(14). doi: 10.3390/ijms22147525. Xu T#, Zhang X, Liu Y, Wang H, Luo J*, Luo Y*, An P*. Effects of dietary polyphenol supplementation on iron status and erythropoiesis: a systematic review and meta-analysis of randomized controlled trials. The American journal of clinical nutrition 2021. doi: 10.1093/ajcn/nqab068. An P#, Xu W#, Luo J* and Luo Y*. Expanding TOR complex 2 signaling: Emerging regulators and new connections. Frontiers in Cell and Developmental Biology 2021. doi: 10.3389/fcell.2021.713806. Wu J#, Lin D#, Jiu L, Liu Q, Gu Z, Luo J*, Zhao Y*. Exploring epigenetic biomarkers of universal specificities and commonalities among pan-cancer cohorts in The Cancer Genome Atlas. Epigenomics 2021;13(8):599-612. doi: 10.2217/epi-2021-0050. Wang Y#, Liu Y#, Zhao Y, Luo J*. Quantification of circadian rhythm in mitochondrial DNA copy number in whole blood, and identification of factors that influence it. Cellular and molecular biology 2020;66(5):179-84. Lin D#, Wang R#, Luo J, Ren F, Gu Z, Zhao Y*, Zhao L*. The Core and Distinction of the Gut Microbiota in Chinese Populations across Geography and Ethnicity. Microorganisms 2020;8(10). doi: 10.3390/microorganisms8101579. Luo J#, Wang Y#, Yuan J#, Zhao Z, Lu J*. MicroRNA duplication accelerates the recruitment of new targets during vertebrate evolution. Rna 2018;24(6):787-802. doi: 10.1261/rna.062752.117. Zhang H#, Dou S#, He F, Luo J, Wei L, Lu J*. Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during Drosophila development. PLoS biology 2018;16(7):e2003903. doi: 10.1371/journal.pbio.2003903. Wang Y, Luo J, Zhang H, Lu J*. microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes. Molecular biology and evolution 2016;33(9):2232-47. doi: 10.1093/molbev/msw089. Luo J#, Song Z#, Yu S, Cui D, Wang B, Ding F, Li S, Dai Y*, Li N*. Efficient generation of myostatin (MSTN) biallelic mutations in cattle using zinc finger nucleases. PloS one 2014;9(4):e95225. doi: 10.1371/journal.pone.0095225. Yu S, Song Z, Luo J, Dai Y, Li N*. Over-expression of RAD51 or RAD54 but not RAD51/4 enhances extra-chromosomal homologous recombination in the human sarcoma (HT-1080) cell line. Journal of biotechnology 2011;154(1):21-4. doi: 10.1016/j.jbiotec.2011.03.023.