个人简介

Emily Smith, associate professor, received her Ph.D. from the University of Wisconsin in 2003. She continued her research as a postdoctoral fellow first at the University of Delaware under Prof. Mary Wirth and then at the University of Arizona under Prof. Danny Brower. She joined the faculty at Iowa State University in 2006.

研究领域

Bioanalytical/Fluorescence and Chemical Imaging

The Smith Group of analytical and bioanalytical chemists develops imaging instrumentation and methods, and they apply these techniques to study enzymatic catalysis, polymer films and the cell membrane. The team uses imaging techniques including fluorescence and Raman scattering. The Smith Group’s research efforts in the laboratory have two main objectives: the development of methods to study cell membrane organization and dynamics, and the development of instrumentation for analysis of enzymatic catalysis and polymer films, which has applications in developing improved biofuels and energy storage and capture devices. The former is funded by the National Science Foundation, Divisions of Chemistry and Molecular Biology, and formerly by the Roy J. Carver Charitable Trust; the latter area of focus is funded by the Department of Energy, Basic Energy Sciences through Ames Laboratory.

近期论文

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Mahoney, K.M.; Goswami, P.P.; Syed, A.; Kolker, P.; Shannan, B.; Smith, E.A.; Winter, A.H. "Self-Immolative Phthalate Esters Sensitive to Hydrogen Peroxide and Light" Journal of Organic Chemistry, 2014, 79 (23), 11740-11743. Lesoine, M.D.; Bobbitt, J.M. Carr, J.A.; Elshobaki, M.; Chaudhary, S.; Smith, E.A. "Quantitative Comparison of the Stability on of High Efficiency Heterojunction Solar Cells" The Journal of Physical Chemistry C, 2014, 118 (51), 30229-30237. Bobbitt, J.M.; Weibel, S.; Smith, E.A. "Fourier Transform Plasmon Waveguide Resonance Spectroscopy" Analytical Chemistry, 2014, 86 (24), 11957-11961. Mainali, D.; Syed, A.; Arora, N.; Smith, E.A. "Role of Insulin Receptor and Insulin Signaling on αPS2CβPS Integrins’ Lateral Diffusion" European Biophysics Journal, 2014, 43 (12), 603-611. Arora, N.; Syed, A.; Sander, S.; Smith, E.A. "Single Particle Tracking with Sterol Modulation Reveals the Cholesterol-mediated Diffusion Properties of Integrin Receptors" Physical Biology, 2014, 11, 066001. Lesoine, M.D.; Bobbitt, J.M.; Smith, E.A. "High Angular-resolution Automated Visible-wavelength Scanning Angle Raman Spectroscopy" Analytica Chimica Acta, 2014, 848, 61-66. Budhi, S.; Peeraphatdit, C.; Pylypenko, S.; Nguyen, V.H.T.; Smith, E.A.; Trewyn, B.G. "Enhanced Metal Loading in SBA-15-type Catalysts Facilitated by Salt Addition: Synthesis, Characterization and Catalytic Epoxide Alcoholysis Activity of Molybdenum Incorporated Porous Silica" Applied Catalysis A: General, 2014, 475, 469-476. Syed, A.; Lesoine, M.D.; Bhattacharjee, U.; Petrich, J.W.; Smith, E.A. "The Number of Accumulated Photons and the Quality of Stimulated Emission Depletion Lifetime Images" Photochemistry and Photobiology, 2014, 90 (4), 767-772. Selected as a Feature Paper. Meyer, M.W.; Larson, K.L.; Mahadevapuram, R.C.; Lesoine, M.D.; Carr, J.A.; Chaudhary, S.; Smith, E.A. "Scanning angle-Raman spectroscopy of poly(3-hexylthiophene)-based films on indium tin oxide, gold and sapphire surfaces" ACS Applied Materials & Interfaces, 2013, Online Version of Record published before inclusion in an issue. Mainali, D.; Smith, E.A. "Select cytoplasmic and membrane proteins increase the percentage of immobile integrins but do not affect the average diffusion coefficient of mobile integrins" Analytical and Bioanalytical Chemistry, 2013, 405 (26), 8561-8568. Stender, A.S.; Marchuk, K.; Liu, C.; Sander, S.; Meyer, M.W. Smith, E.A.; Neupane, B.; Wang, G.; Li, J.; Cheng, J.-X.; Huang, B.; Fang, N. "Single Cell Optical Imaging and Spectroscopy" Chemical Reviews, 2013, 113 (4), 2469-2527. Invited review for the April 2013 thematic issue on "New Frontiers in Bioanalytical Chemistry". Lesoine, M.D.; Bhattacharjee, U.; Guo, Y.; Vela, J.; Petrich, J.W.; Smith, E.A. "Subdiffraction, Luminescence-Depletion Imaging of Isolated, Giant, CdSe/CdS Nanocrystal Quantum Dots" J. Phys. Chem. C, 2013, 117, (7) 3662-3667. Meyer, M.W.; Smith, E.A. "Scanning Angle Total Internal Reflection Raman Spectroscopy of Thin Polymer Films" MRS Online Proceedings Library, 2013, 1522, mrsf12-1522-pp03-04 doi:10.1557/opl.2013.133 Meyer, M.W.; McKee, K.J.; Nguyen, V.H.T.; Smith, E.A. "Scanning Angle Plasmon Waveguide Resonance Raman Spectroscopy for the Analysis of Thin Polystyrene Films" J. Phys. Chem. C., 2012, 116, (47) 24987-24992. Meyer, M.W.; Nguyen, V.H.T.; Smith, E.A. "Scanning Angle Raman Spectroscopy Measurements of Thin Polymer Films for Thickness and Composition Analyses" Vibrational Spectroscopy, 2012, 64, 94-100. Mainali, D.; Smith, E.A. "The Effect of Ligand Affinity on Integrins̕ Lateral Diffusion in Cultured Cells" European Biophysics Journal, 2013, 42, (4) 281-90. McKee, K.J.; Meyer, M.W.; Smith, E.A. "Plasmon Waveguide Resonance Raman Spectroscopy" Analytical Chemistry, 2012, 84, (21) 9049-9055. Arora, N.; Mainali, D.; Smith, E.A. "Unraveling the Role of Membrane Proteins Notch, Pvr and EGFR in Altering Integrin Diffusion and Clustering" Analytical and Bioanalytical Chemistry, 2012, 404 (8) 2339-2348. Lesoine, M.D.; Bose, S.; Petrich, J.W.; Smith, E.A. "Super-continuum Stimulated Emission Depletion (STED) Fluorescence Lifetime Imaging" J. Phys. Chem. B, 2012, 116, (27) 7821-7826. Lupoi, J.; Smith, E.A. "Characterization of Woody and Herbaceous Biomass' Polysaccharide and Lignin Composition with 1064 nm Dispersive Multichannel Raman Spectroscopy" Applied Spectroscopy, 2012, 66, (8) 903-910.