个人简介

Charles E. Bowers Faculty Teaching Award, 2006 Best Instructor in Chemistry by the IT Student Board, 1999 Minnesota Award of the American Chemical Society Minnesota Section , 1997 Honored at the Wayland E. Noland Symposium, U of M, 1996 Distinguished Service Medal, U of M Chapter of Sigma Xi, 1994 Fellow, American Association for the Advancement of Science, 1987 IT Distinguished Teaching Award, 1964

研究领域

Organic Chemistry

Research in Dr. Noland’s group is focused on heterocyclic nitrogen chemistry and the chemistry of nitro compounds, with emphasis on synthesis, mechanisms, and submission of compounds for testing for medicinal activity. To date, activity has been found against cancer (in two classes of compounds), AIDS, tuberculosis, and plants, including fungi. Currently, emphasis is also being placed on the synthesis of benzofurazan oxides, nitriles, isonitriles, and their analogs, to observe interactions, especially with halogens, in the crystalline state. This is being carried out in a fruitful collaboration with Prof. Emeritus Doyle Britton, who founded the departmental X-ray crystallographic laboratory.

近期论文

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D. Britton, W. E. Noland, M. J. Pinnow, and V. G. Young, Jr., "Crystal Packing: An Examination of the Packing of Molecules Approximately Isosteric with 4,5-Dichlorophthalic Anhydride", Helv. Chim. Acta, 86,1175-1192 (2003) (Jack D. Dunitz 80th Birthday Festschrift). W. E. Noland, K. P. Cole, and D. Britton, "4,5-Dibromo-l-methyl-lH-imidazole", Acta Crystallogr., E59, 458-460 (2003). W. E. Noland, K. P. Cole, and D. Britton, "Five (1H-Pyrrol-2-yl) pyridines", Acta Crystallogr., C59, 263-267 (2003). W. E. Noland, "Richard T. Arnold (An Obituary Biography)", Minn. Chemist, 56, No. 1, pp. 8-9, Jan., 2003. W. E. Noland and B. L. Kedrowski, "Reactivity of Nitrovinylquinones with Cyclic and Acyl Enol Ethers", J. Org. Chem., 67, 8366-8373 (2002). D. Britton, W. E. Noland, and T. K. Henke, "2.6-Dibromo-4-fluorobenzonitrile," Acta Crystallogr., E58,185-187 (2002). W.E. Noland and B.L. Kedrowski, "Quinone Approaches Toward the Synthesis of Aflatoxin B2," Org. Lett., 2, 2109-2111 (2000). M. Pink, D. Britton, W.E. Noland, and M.J. Pinnow, "2,4,6-Trichlorophenyliso-nitrile and 2,4,6-Trichlorobenzonitrile," Acta Crystallogr., C56,1271-1273 (2000). D. Britton, W.E. Noland, and M.J. Pinnow, "Isomorphism and Pseudosymmetry in 2,6-Dichloro- and 2,6-Dibromobenzonitrile," Acta Crystallogr., B56,822-827 (2000).