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个人简介

学习经历 1997年9月-2001年6月 中国农业大学动物科技学院 动物遗传育种专业本科 2001年9月-2006年7月 中国农业大学动物科技学院 动物遗传育种与繁殖专业博士研究生 工作经历 2022年至今 中国农业大学动物科技学院 教授 2010年-2021年 中国农业大学动物科技学院 副教授 2006年-2009年 中国农业大学动物科技学院 讲师 其中: 2011年-2012年 美国爱荷华州立大学 访问学者 2007年 意大利Spallanzani畜牧研究所 访问学者 获得奖励与荣誉 北京市科技进步奖二等奖, 中国荷斯坦牛分子育种关键技术研究与应用,2011,排名6/15 北京市科技进步奖一等奖, 中国荷斯坦牛基因组选择技术平台的建立与应用,2015,排名15/15 新疆维吾尔自治区科技进步奖三等奖,新疆褐牛、西门塔尔牛蜘蛛腿综合征致病基因的检测技术研究与应用,2020,排名3/10 中国农业大学优秀教师,2021 动物科技学院“最美思政示范课”二等奖,《动物育种学实验》,2021 动物科技学院优秀博士学位论文奖,梁栋《水牛白毛色性状分子机制及进化研究》,2020 吴常信动物遗传育种奖励基金会动物遗传育种优秀论文奖,《全基因组测序挖掘奶牛胚胎致死基因突变》,2021 2019年入选中国农业大学“人才培育发展支持计划”青年新星A类(特聘研究员) 2020年入选中国农业大学动物科技学院青年英才计划A类

研究领域

奶牛基因组育种技术,牛群体基因组学

近期论文

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Yang Y, Si J, Lv X, Dai D, Liu L, Tang S, Wang Y, Zhang S, Xiao W, Zhang Y. Integrated analysis of whole genome and transcriptome sequencing reveals a frameshift mutation associated with recessive embryonic lethality in Holstein cattle. Animal Genetics. 2021. doi: 10.1111/age.13160. (Corresponding author) Khan MYA, Omar AI, He Y, Chen S, Zhang S, Xiao W, Zhang Y. Prevalence of nine genetic defects in Chinese Holstein cattle. Veterinary Medicine and Science, 2021,7(5):1728-1735. (Corresponding author) Liang D, Zhao P, Si J, Fang L, Pairo-Castineira E, Hu X, Xu Q, Hou Y, Gong Y, Liang Z, Tian B, Mao H, Yindee M, Faruque MO, Kongvongxay S, Khamphoumee S, Liu GE, Wu D, Barker JSF, Han J, Zhang Y. Genomic analysis revealed a convergent evolution of LINE-1 in coat color: A case study in water buffaloes (Bubalus bubalis). Molecular Biology and Evolution, 2021, msaa279. (Co-orresponding author) Freitas PH, Wang Y, Yan P, Oliveira HR, Schenkel FS, Zhang Y, Xu Q, Brito LF. Genetic Diversity and Signatures of Selection for Thermal Stress in Cattle and Other Two Bos Species Adapted to Divergent Climatic Conditions. Frontiers in Genetics. 2021, 12:102. (Co-corresponding author) Rafiepour M, Ebrahimie E, Vahidi MF, Salekdeh GH, Niazi A, Dadpasand M, Liang D, Si J, Ding X, Han J, Zhang Y, Qanbari S. Whole genome re-sequencing reveals adaptation prior to the divergence of buffalo subspecies. Genome Biology and Evolution, 2021, 13(1):evaa231. (Co-corresponding author) Yan Z, Huang H, Freebern E, Santos DJA, Dai D, Si J, Ma C, Cao J, Guo G, Liu GE, Ma L, Fang L, Zhang Y. Integrating RNA-Seq with GWAS reveals novel insights into the molecular mechanism underpinning ketosis in cattle. BMC Genomics, 2020, 21, 489. (Co-corresponding author) Zhang Y, Colli L, Barker JSF. Asian water buffalo: domestication, history and genetics. Animal Genetics, 2020, 51(2):177-191. (Co-first author, corresponding author) Zhang Y, Liang D, Huang H, Yang Z, Wang Y, Yu Y, Liu L, Zhang S, Han J, Xiao W. Development and application of KASP assays for rapid screening of eight genetic defects in Holstein cattle. Journal of Dairy Science, 2020, 103(1):619–624. (Co-first author and co-corresponding author) Luo X, Zhou Y, Zhang B, Zhang Y, Wang X, Feng T, Li Z, Cui K, Wang Z, Luo C, Li H, Deng Y, Lu F, Han J, Miao Y, Mao H, Yi X, Ai C, Wu S, Li A, Wu Z, Zhuo Z, Giang DD, Mitra B, Vahidi MF, Mansoor S, Al-Bayatti SA, Sari EM, Gorkhali NA, Prastowo S, Shafique L, Ye G, Qian Q, Chen B, Shi D, Ruan J & Liu Q. Understanding divergent domestication traits from the whole-genome sequencing of swamp-and river-buffalo populations. National Science Review, 2020, 7(3), 686-701. (Co-first author) Huang H, Cao J, Guo G, Li X, Wang Y, Yu Y, Zhang S, Zhang Q, Zhang Y. Genome-wide association study identifies QTLs for displacement of abomasum in Chinese Holstein cattle. Journal of Animal Science, 2019, 97(3): 1133-1142. (Corresponding author) Huang H, Cao J, Hanif Q, Wang Y, Yu Y, Zhang S, Zhang Y. Genome-wide association study identifies energy metabolism genes for resistance to ketosis in Chinese Holstein cattle. Animal Genetics, 2019, 50(4):374-380. (Corresponding author) Hanif Q, Farooq M, Amin I, Mansoor S, Zhang Y, Mahmood Khan QM. In silico identification of conserved miRNAs and their selective target gene prediction in indicine (Bos indicus) cattle. PloS ONE, 2018, 13(10):e0206154. (Co-corresponding author) Wu D, Ding X, Wang S, Wo?jcik JM, Zhang Y, Tokarska M, Li Y, Wang M, Faruque O, Nielsen R, Zhang Q and Zhang Y. Pervasive introgression facilitated domestication and adaptation in the Bos species complex. Nature Ecology & Evolution, 2018, 2(7):1139-1145. (Co-first author) Gao Y, Gautier M, Ding X, Zhang H, Wang Y, Wang X, Faruque MO, Li J, Ye S, Gou X, Han J, Lenstra JA, Zhang Y. Species composition and environmental adaptation of indigenous Chinese cattle. Scientific Reports. 2017, 7:16196. (Corresponding author) Zhang Y, Lu Y, Yindee M, Li K, Kuo H, Ju Y, Ye S, Faruque MO, Li Q, Wang Y, Cuong VC, Pham LD, Bouahom B, Yang B, Liang X, Cai Z, Vankan D, Manatchaiworakul W, Kowlim N, Duangchantrasiri S, Wajjwalku W, Colenbrander B, Zhang Y, Beerli P, Lenstra JA, Barker JSF. Strong and stable geographic differentiation of swamp buffalo maternal and paternal lineages indicates domestication in the China/Indochina border region. Molecular Ecology, 2016, 25(7):1530-1550. Zhang Y, Guo G, Huang H, Lu L, Wang L, Fang L, Liu L, Wang Y, Zhang S. Screening for JH1 genetic defect carriers in Jersey cattle by a polymerase chain reaction and restriction fragment length polymorphism assay. Journal of Veterinary Diagnostic Investigation, 2015, 27(5): 596-599. Fan Y, Wang P, Fu W, Dong T, Qi C, Liu L, Guo G, Li C, Cui X, Zhang S, Zhang Q, Zhang Y, Sun D. Genome-wide association study for pigmentation traits in Chinese Holstein population. Animal Genetics, 2014, 45(5): 740-744. (Co-corresponding author) Zhang Y, Li Q, Ye S, Faruque MO, Yu Y, Sun D, Zhang S, Wang Y. New variants in the melanocortin 1 receptor gene (MC1R) in Asian cattle. Animal Genetics, 2014, 45(4): 609-610. Zhang Y, Barker JSF, Vankan D. The swamp buffalo: domestication, dispersal, and genetic differentiation. Buffalo Bulletin, 2013, 32:671-674. Zhang Y, Fan X, Sun D, Wang Y, Yu Y, Xie Y, Zhang S, Zhang Y. A novel method for rapid and reliable detection of complex vertebral malformation and bovine leukocyte adhesion deficiency in Holstein cattle. Journal of Animal Science and Biotechnology, 2012, 3(1): 24. Zhang Y, Vankan D, Zhang Y, Barker JSF. Genetic differentiation of water buffalo (Bubalus bubalis) populations in China, Nepal and south-east Asia: inferences on the region of domestication of the swamp buffalo. Animal Genetics, 2011, 42, 366–377. 颜泽,肖炜,张胜利,王雅春,张毅. 基于KASP技术的牛3种无角基因联合检测方法研究. 农业生物技术学报,2021,29(03):610-618. 张可,纪皓楠,柴河,姜立鑫,赵曼,佟彬,郭峰,吴宏军,刘爱荣,王雅春,张毅. 三河牛无角基因鉴定及来源探析. 中国畜牧杂志,2021,57(11):67-71. 和玉伟,Abdullah Ibne Omar,陈绍祜,吕小青,刘林,张胜利,肖炜,张毅. 北京地区奶牛HH6遗传缺陷基因分布初探. 中国奶牛,2021(06):13-17. 孙愉洪,王铭正,肖炜,张胜利,张毅.荷斯坦牛HH5遗传缺陷基因快速检测方法的建立及应用.中国奶牛,2020(05):18-22. 张毅,孙东晓,肖炜,张胜利.影响荷斯坦牛繁殖力及犊牛健康的遗传缺陷基因研究进展.中国畜牧杂志,2020,56(08):1-8. 司敬方,刘云鹏,董刚辉,朱克成,黄河天,王炎,李锡智,曹杰,王雅春,张毅.利用产前瘤胃反刍时间预测奶牛围产期酮病风险.中国农业大学学报,2019,24(08):78-87. 劳兰兰,吕小青,刘林,肖炜,张毅.国内荷斯坦种公牛HH4遗传缺陷基因筛查.中国畜牧杂志,2017,53(12):33-36. 杨湛澄,闫青霞,黄河天,陈绍祜,张胜利,张毅.中国荷斯坦公牛系谱完整性研究.中国奶牛,2017(02):22-25. 杨湛澄,黄河天,闫青霞,王雅春,俞英,陈绍祜,孙东晓,张胜利,张毅.利用高密度SNP标记分析中国荷斯坦牛基因组近交.遗传,2017,39(01):41-47. 梁栋,唐韶青,高薇,杨湛澄,马浩,刘林,肖炜,张毅.北京地区奶牛场选配技术应用现状调查.中国奶牛,2016(04):17-22.

学术兼职

全国奶牛遗传改良计划专家委员会,成员 第三次全国畜禽遗传资源普查牛专业组,成员/办公室主任 畜禽良种产业技术创新战略联盟,副秘书长 中国畜牧兽医学会动物遗传标记学会,理事 中国奶业协会育种委员会理事,遗传评估工作组成员 国际水牛联合会,执委会成员 Egyptian Journal of Animal Production,国际编委

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