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个人简介

学习经历 1997.9-2000.7 中国农业科学院,动物营养与饲料科学专业,获博士学位 1992.9-1995.7 西北农林科技大学,动物遗传育种专业,获硕士学位 1988.9-1992.7 内蒙古民族大学,畜牧学专业,获学士学位 工作经历 2011.12-至今 中国农业大学,教授/研究员 2012.10-2013.10 加州大学洛杉矶分校(UCLA),干细胞表观遗传与分化,访问学者 2004.6-2011.12 中国农业大学,副研究员 2002.1-2004.6 中国农业大学,博士后流动站,动物分子营养学,博士后 1995.7-2004.6 西北农林科技大学,助教、讲师 获得奖励与荣誉 2015年获国家科技进步二等奖“荣昌猪品种资源保护与开发利用”(2015-J-203-2-01-R04) 2012年获重庆市政府科技进步一等奖,“荣昌猪品种资源开发关键技术研究与产业化示范(2011-J-1-04-R03)”

研究领域

动物营养与肉品质

近期论文

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Wang L, He T, Zhang X, Wang YB, Qiu K, Jiao N, He LJ, Yin JD?. 2021. Global transcriptomic analysis reveals Lnc-ADAMTS9 exerting an essential role in myogenesis through modulating the ERK signaling pathway. J Anim Sci Biotech. l4.1672021. DOI: 10.1186/s40104-020-00524-4 Zhang X, Xu DD, Chen MX, Wang YB, He LJ, Wang L, Wu JW, and Yin JD? 2021. Impact of dietary nutrient intake on insulin sensitivity in the skeletal muscle and its application to early prevention of type 2 diabetes mellitus. Adv Nutr. 2021 Jul 30; 12(4):1305-1316. doi: 10.1093/advances/nmaa161. Zhang X #, Sun WJ#, He LJ, Wang LQ, Qiu K and Yin JD?. 2020. Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs. Stem Cell Research & Therapy. 11:536 https://doi.org/10.1186/ s13287-020-02053-3 Qiu K, Xu DD, Wang LQ, Zhang X, Jiao N, Gong L, Yin JD?.2020. Association analysis of single-cell RNA sequencing and proteomics reveals a vital role of Ca2+ signaling in the determination of skeletal muscle development potential. Cells. 2020, 9(4): 1045; doi:10.3390/cells9041045DOI Jiao N, Xu DD, Qiu K, Wang LQ, Wang L, Piao Xsh, Yin JD?. 2020. Restoring mitochondrial function and normalizing ROS-JNK/MAPK pathway exert key roles in glutamine ameliorating bisphenol A-induced intestinal injury. FASEB J. 34(6):7442-7461. doi: 10.1096/fj.201902503R. Xu D, Wang Y, Jiao N, Qiu K, Zhang X, Wang L, Wang L, Yin JD?. 2020. The coordination of dietary valine and isoleucine on water holding capacity, pH value and protein solubility of fresh meat in finishing pigs. Meat Sci 163 (2020) 108074 https://doi.org/10.1016/j.meatsci.2020.108074 Epub 2020 Jan 28 Jingdong Yin? and Zhengpeng Zhu. 2020. Perspectives for the future in China: challenges and opportunities facing animal teaching, research, and industry. Anim Front, 10(3):46-48. doi: 10.1093/af/vfaa019. Huang C, Wang Y, He X, Jiao N, Zhang X, Qiu K, Piao X, Yin JD?. 2019. The involvement of NF-κB/P38 pathways in scutellaria baicalensis extracts attenuating of Escherichiacoli K88-induced acute intestinal injury in weaned piglets. Br J Nutr. 28; 122(2):152-161. doi: 10.1017/S0007114519000928. Epub 2019 Jul 25. Zhang X, Wang LQ, Qiu K, Xu DD, and Yin JD?. 2019. Dynamic Membrane Proteome of Adipogenic and Myogenic Precursors in Skeletal Muscle Highlights EPHA2 May Promote Myogenic Differentiation through ERK Signaling. FASEB J. 33(4):5495-5509. doi: 10.1096/fj.201801907R. Luo YH, Zhang X, Zhu ZP, Jiao N, Qiu K and Yin JD?.2018. Surplus dietary isoleucine intake enhanced monounsaturated fatty acid synthesis and fat accumulation in skeletal muscle of finishing pigs. J Anim Sci Biotech. 9:88 https://doi.org/10.1186/s40104-018-0306-5 Qiu K, Zhang X, Wang LQ, Jiao N, Xu DD, Yin JD?. 2018. Protein expression landscape defines the differentiation potential specificity of adipogenic and myogenic precursors in the skeletal muscle.J Proteome Res. Article ASAP DOI: DOI: 10.1021/acs.jproteome.8b00530. Zhang X, Qiu K, Wang LQ, Xu DD, and Yin JD?. 2018.Integrated remodeling of gut-liver metabolism induced by moderate protein restriction contributes to improvement of insulin sensitivity. Mol Nutr Food Res. 62(19):e1800637. doi: 10.1002/mnfr.201800637. JW Wang, CF Qin, T He, K Qiu, WJ Sun, X Zhang, N Jiao, WY Zhu, Yin JD?. 2018. Alfalfa-containing diets alter luminal microbiota structure and short chain fatty acid sensing in the caecal mucosa of pigs. J Anim Sci Biotech. 2018 Jan 9; 9: 11. doi: 10.1186/s40104-017-0216-y. Qiu K, Zhang X, Jiao N, Xu DD, Huang CY, Wang YB, Yin JD?. 2018. Dietary protein level affects nutrient digestibility and ileal microbiota structure in growing pigs. Anim Sci J. 89(3):537-546. DOI:10.1111/asj.12946. Sun WJ, He T, Qin CF, Qiu K, Zhang X, Luo YH, Li DF, Yin JD ?. 2017. A potential regulatory network underlying distinct fate commitment of myogenic and adipogenic cells in skeletal muscle. Sci Rep. 7:44133. doi: 10.1038/srep44133. Qin CF, Qiu K, Sun W, Jiao N, Zhang X, Che L*, Zhao H, Shen H, Yin JD?.2016. A proteomic adaptation of small intestinal mucosa in response to dietary protein limitation. Sci Rep. 6:36888.| DOI: 10.1038/srep36888 Zhou Q, Sun W, Liu X, Wang X, Xiao Y, Bi D, Yin JD?, Shi D?. 2016. Third- generation sequencing and analysis of four complete pig liver esterase gene sequences in clones identified by screening BAC library. PLoS One. Oct 3;11(10):e0163295. doi: 10.1371/journal.pone.0163295. Qiu K, Qin CF, Luo M, Zhang X, Sun WJ, Jiao N, Li DF, Yin JD?.2016. Protein restriction with amino acid-balanced diets shrinks circulating pool size of amino acid by decreasing expression of specific transporters in the small intestine. PLoS One. Sep 9;11(9):e0162475. doi: 10.1371/journal.pone.0162475. Qin CF, Huang P, Qiu K, Sun WJ, Xu L, Zhang X, and Yin JD?. 2015. Influences of dietary protein sources and crude protein levels on intracellular free amino acid profile in the longissimus dorsi muscle of inishing gilts. J Anim Sci Biotech.7(2)184-193. 6:52 DOI 10.1186/s40104-015-0052-x Yu G, Xiang H, Tian J, Yin JD, Pinkert CA, Li Q, Zhao X.2015. Mitochondrial haplotypes influence metabolic traits in porcine transmitochondrial cybrids. Sci Rep. Aug 19;5:13118. doi: 10.1038/srep13118. Liu Y, Lv W, Yu B, Ju T, Yang F, Jiang M, Liu Z, Xu L, Sun W, Huang J, Li D, Yin JD?. 2013. S-Adenosylmethionine-induced adipogenesis is accompanied by suppression of Wnt/β-catenin and Hedgehog signaling pathways. Mol Cell Biochem. 382(1-2):59-73. Liu Y, Chen F, Odle J, Lin X, Zhu H, Shi H, Hou Y, Yin JD?. 2013. Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge. J Nutr. 143(8):1331-9. Chen J, Fu R, Cui Y, Li YS, Pan JR, Liu JL, Luo HS, Yin JD, Li DF, Cui S. 2013. LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice. J Biol Chem. 288(17):12395-405. Fu R, Liu JL, Fan JJ, Li RG, Li DF, Yin JD?, Cu S?. 2012. Evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line. J Cell Physiol. 227: 98–107. Lv W, Ju T, Dong B, Yu B, Yin JD?.2012. Effect of dietary stable isotopic ratios of carbon and nitrogen on the extent of their incorporation into tissues of rats. J Anim Sci Biotechnol., 3(1):14. Yang HS, Li FN, Kong XF, Yuan XX, Lian GQ, Geng MM, Li TJ, Yin JD?, and Yin YL?. 2012. Molecular cloning, tissue distribution and ontogenetic expression of Xiang pig Chemerin and its involvement in regulating energy metabolism through Akt and ERK1/2 signaling pathways. Mol Biol Rep., 39(2):1887-94. Wang Q, Ji C, Huang JX, Yang FY, Zhang HY, Liu L, Yin JD?.2011. The mRNA of lipin1 and its isoforms are differently expressed in the longissimus dorsi muscle of obese and lean pigs. Mol Biol Rep. 38(1):319-325. Li FN, Yin JD?, Ni JJ, Liu L, Zhang HY, and Du M. 2010. Chloride intracellular channel 5 modulates adipocyte accumulation in skeletal muscle by inhibiting preadipocytes differentiation. J Cell Biochem. 110 (4): 1013-1021 Peng Y, Ren F, Yin JD?, Fang Q, Li F N, and Li DF. 2010. Transfer of conjugated linoleic acid from the sows to their offspring and its impact on the fatty acid profiles of plasma, muscle, and subcutaneous fat in piglets. J Anim Sci. 88:1741-1751. Li FN, Yin JD ?, Yue T, Liu L and Zhang HY. 2010. The chloride intracellular channel 5 (CLIC5) involved in C2C12 myoblasts proliferation and differentiation. Cell Biol Internat. 34(4):379-384. Yue T, Fang Q, Yin JD?, Li FN. 2010. High glucose induces differentiation and adipogenesis in porcine muscle satellite cells via mTOR. BMB reports. 43(2): 140-145. Liu L, Yin JD?, Li W, Liu K, Peng Y, Tan PP, Ma RLZ?. 2010. Construction of a Bacterial Artificial Chromosome Library for the Rongchang Pig Breed and its Use for the Identification of Genes Involved in Intramuscular Fat Deposition. Biochem Bioph Res Co.,391: 1280–1284. Fang Q, Yin JD?, Li FN, Zhang JX, Watford M. 2010. Characterization of methionine adenosyltransferase 2b gene expression in skeletal muscle and subcutaneous adipose tissue from obese and lean pigs. Mol Biol Rep, 37:2517–2524. Du M, Yin JD, Zhu MJ. 2010. Cellular signaling pathways regulating the initial stage of adipogenesis and arbling of skeletal muscle. Meat Sci. 2010: 86(1):103-109. Han P, Ma X, Yin JD. 2010. The effects of lipoic acid on soybean beta-conglycinin- induced anaphylactic reactions in a rat model. Arch Anim Nutr, 64(3):254-264. Yu J, Yin P, Yin JD, Liu F, Zhu X, Cheng G, Guo K, Yin Y, Xu J.2010. Involvement of ERK1/2 signalling and growth-related molecules' expression in response to heat stress-induced damage in rat jejunum and IEC-6 cells. Int J Hyperthermia, 26(6): 538-555. Yue T, Qian F, Yin JD?, Li DF, Li W. 2010. S-adenosylmethionine stimulates fatty acid metabolism-linked gene expression in porcine muscle satellite cells. Mol Biol Rep., 37(7):3143-3149. Epub 2009 Oct 14. Yin JD?, Li XL, Li DF, Yue T, Fang Q, Ni JJ, Zhou X, and Wu G. 2009. Dietary supplementation with zinc oxide stimulates ghrelin secretion from the stomach of pigs. J Nutr Biochem, 20 (10):783-790. Liu FH, Yin JD, Du M., Yan P, Xu JQ, Zhu X, and Yu J. 2009. Heat-stress-induced damage to porcine small intestinal epithelium associated with downregulation of epithelial growth factor signaling1. J Anim Sci., 87(6): 1941-1949. Yin JD and Li DF. 2009. Nutrigenomics Approach-A Strategy in Identification of Nutrition Responsive Genes Influencing Meat Edible Quality Traits in Swine. Asian- Austr J Anim Sci, 22 (4):605-610. Wang X, Ou D, Yin JD, Wu G, Wang J. 2009. Proteomic analysis reveals altered expression of proteins related to glutathione metabolism and apoptosis in the small intestine of zinc oxide- supplemented piglets. Amino Acids, 37(1):209-218. Zhang JX, Yin JD?, Zhou X, Li FN, Ni JJ, Dong B. 2008. Effects of lower dietary lysine and energy content on carcass characteristics and meat quality in growing-finishing pigs. Asian- Austr J Anim Sci, 21(12):1785-1793. Yin JD, Shang XG, Li DF, Wang FL, Guang YF, Wang ZY. 2008.Effects of Dietary Conjugated Linoleic Acid on the Fatty Acid Profile and Cholesterol Content of Egg Yolks from Different Breeds of Layers. Poult Sci, 87:284-290. Li ZJ, Yi GF, Yin JD?, Sun P, Li DF and Chris Knight. 2008. Effects of organic acids on growth performance, gastrointestinal pH, intestinal microbial populations and immune responses of weaned pigs. Asian-Austr J of Anim Sci, 21:252-261. Lu P, Zhang LY, Yin JD, Everts AKR, Li DF*. 2008. Effects of soybean oil and linseed oil on fatty acid compositions of muscle lipids and cooked pork flavour. Meat Sci, 80: 910-918. Zhang HW, Yin JD, Li DF,Zhou X and Li XL. 2007. Tryptophan enhances ghrelin expression and secretion associated with increased food intake and weight gainin weaning pigs. Domest Anim Endocrinol, 33(1):47-61. Lu P, Li DF, Yin JD, Zhang LY, Wang ZY. 2007. Flavour differences of cooked longissimus muscle from Chinese indigenous pig breeds and hybrid pig breed (Duroc * Landrace * Large White). Food Chem, 107: 1529-1537. Zhou X, Li DF*, Yin JD?, Ni JJ, Dong B, Zhang JX and Du Min. 2007. Conjugated linoleic acid differently regulates adipogenesis in stromal vascular cells from subcantenous adipose tissue and skeletal muscle of neonatal pigs. J Lipid Res, 48(8):1701-1709. Ou DY, Li DF*, Cao YH, Li XL, Yin JD?, Qiao SHY and Wu GY*.2007. Dietary supplementation with zinc oxide decrease expression of the stem cell factor in the small intestine of weaning pigs. J Nutr Biochem, 18(12):820-827. Chen XJ, Li DF*, Yin JD?, Ding YH, Zhang HL and Yi GF.2006. Regulation of dietary energy level and oil source on leptin and its long form receptor mRNA expression of the adipose tissues in growing pigs. Domest Anim Endocrinol, 31(3):269-283. Li XL, Yin JD, Li DF, Chen XJ, Zang JJ and Zhou X. 2006. Dietary supplementation with zinc oxide increases IGF-I and IGF-I receptor gene expression in the small intestine of weanling piglets. J Nutr, 136 (7): 1786-1791. Lai CHH, Yin JD, Li DF, Zhao LD, Piao XSH and Xing JJ.2005. Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs with lipopolysaccharide. J Nutr, 135(2):239-244. Lai CHH, Yin JD, Li DF, Zhao LD, Chen XJ. 2005. Effects of dietary conjugated linoleic acid supplementation on performance and immune function of weaned pigs. Arch Anim Nutr, 59:41-51. Zhao LD, Yin JD, Li DF, Lai CHH, Chen XJ and Ma D. 2005. Conjugated linoleic acid can prevent tumor necrosis factor gene expression by inhibiting nuclear factor binding activity in peripheral blood mononuclear cells from weaned pigs challenged with lipopolysaccharide. Arch Anim Nutr, 59(6):429-438. Shang XG, Wang FL, Li DF, Yin JD, Li XJ and Yi GF.2005. Effect of dietary conjugated linoleic acid on the fatty acid composition of egg yolk, plasma and liver as well as hepatic stearoyl-coenzyme A desaturase activity and gene expression in laying hens. Poult Sci, 84 (12):1886-1892. Zhu YZ, Li DF, Wang FL, Yin JD and Jin H.2004. Nutritional assessment and fate of DNA of Soybean meal from Roundup ready or conventional soybeans using rats. Arch Anim Nutr, 58:295-310. Shang XG, Wang FL, Li DF, Yin JD and Li JY. 2004. Effects of dietary conjugated linoleic acid on the productivity of laying hens and egg quality during refrigerated storage. Poult Sci, 83 (10):1688-1695. Yin JD, Qi GH, Zheng JJ and Huo QG. 2002. Influence of dietary isoflavnoids on stability of egg yolk lipids, Agri Sci China, 1(10):1180-1184. 何鑫,王璐,王宇波,尹靖东?. 2020.饲粮中添加半胱胺螯合锌对肥育猪肉品质和氨基酸组成的影响. 动物营养学报2020,32,(11):5117-5127 王宇波,许豆豆,何鑫,董冰,尹靖东?.2019.低蛋白饲粮缬氨酸水平对肥育猪生长性能、胴体性状和肉品质的影响. 畜牧兽医学报,2019,50(9):1832-1840.  尹靖东. 2017.畜牧业减少氮排放的营养策略与需要解决的问题.中国畜牧杂志,53 (2):1-3. 何婷,邱凯,张鑫,王宇波,尹靖东?.2017.日粮中添加丁酸梭菌对猪氨基酸全肠道表观消化率及血脂组成的影响.畜牧兽医学报,48(7):1241-50 罗燕红、张鑫、覃春富、焦宁、尹靖东?.2017 .饲粮异亮氨酸水平对肥育猪生长性能、胴体性状和肉品质的影响.动物营养学报29(6) 1884-93. 王嘉为,张蕾,祝皎月,王宇波,尹靖东?,朱伟云?. 2016.饲粮中添加苜蓿草粉对生长猪结肠微生物区系及其代谢产物的影响. 动物营养学报,28(9): 2715-2723. 姜美华,巨婷婷,刘 洋,许玲,孙文娟,赵泮峰,尹靖东?.2013.成肌细胞成脂过程中PPARγ、C/EBPa和Myogenin基因启动子的甲基化变化. 中国农业科学,46(4):3010-3021. 巨婷婷,吕文涛,于渤洋,刘洋,姜美华, 许玲,赵泽平, 尹靖东?.2012.小鼠胞内氯离子通道5基因启动子核心功能区域鉴定及转录调控分析.中国农业大学学报.17(5):137-143 于渤洋,吕文涛,巨婷婷,刘 洋,姜美华,尹靖东?.2012.腺苷甲硫氨酸对成肌细胞成脂分化及脂肪沉积的影响. 中国农业科学,45(18):3841—3848. 朱元招,尹靖东?,李德发,王凤来.2005. 生长猪对转基因豆粕外源DNA的代谢的研究. 畜牧兽医学报,36(10):1083-1086. 尹靖东,齐广海,张萍,霍启光.2004.大豆黄酮对鸡蛋胆固醇及其耐氧化性的影响,中国农业科学,37(5):756-761. 尹靖东,齐广海,郑君杰,霍启光.2003.类黄酮鸡蛋蛋黄脂质稳定性的影响及其机理研究,中国农业科学,36(4):438-442. 尹靖东,齐广海,霍启光.2002.类黄酮对蛋鸡脂类代谢的影响.畜牧兽医学报,33(3):215-220. 尹靖东,齐广海,霍启光.2001.日粮中添加微量组分对鸡蛋胆固醇含量的影响.西北农林科技大学学报(自然科学版),29(3):13-18. 著作 尹靖东主编,2011,编著《动物肌肉生物学与肉品科学》(ISBN978-7-5655-0458-7),中国农业大学出版社 尹靖东副主编,2003,《猪的营养》(第二版)(ISBN7-80167-516-9),中国农业科技出版社 尹靖东主译,2014,《猪的可持续营养》(ISBN978-7-109-20721-9),中国农业出版社

学术兼职

中国畜牧兽医学会 理事 中国畜牧兽医学会动物营养学分会 常务理事、秘书长

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