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1.Han, R; Li, SH; Li, X; Yang, WL. PINK1/Parkin-mediated mitophagy: differences between in vitro and in vivo models. Autophagy, 2022, doi: 10.1080/15548627.2022.2139080. (Corresponding author)
2. Yang W*, Guo X, Tu Z, Chen X, Han R, Liu Y, Yan S, Wang Q, Wang Z, Zhao X, Zhang Y, Xiong X, Yang H, Yin P, Wan H, Chen X, Guo J, Yan XX, Liao L, Li S, Li X-J*. PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis. Protein Cell. 13(1):26-46, 2021. (#co-corresponding author)
3. Yang W*, Liu Y*, Tu Z, Xiao C, Yan S, Ma X, Guo X, Chen X, Yin P, Yang Z, Jiang T, Li, S, Qin C, Li X-J. CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys. Cell Res. 29(4):334-336, 2019. (co-first author)
4. Yin P, Li SH, Li X-J, Yang W*. New pathogenic insights from large animal models of neurodegenerative diseases. Protein Cell. doi: 10.1007/s13238-022-00912-8, 2022. (Corresponding author)
5.Yang W, Li S, Li X-J. A CRISPR monkey model unravels a unique function of PINK1 in primate brains. Mol Neurodegener. 14(1):17, 2019.
6. Chen, X; Wang, Q; Li, S; Li, XJ; Yang, WL. Mitochondrial-Dependent and Independent Functions of PINK1. Frontiers in Cell and Developmental Biology, 2022, 10:954536. (Corresponding author)
7.Yang W#, Chen X, Li S, Li X-J#. Genetically modified large animal models for investigating neurodegenerative diseases. Cell Biosci. 11(1):218, 2021. (#co-corresponding author)
8.Yang, WL#; Li, S; Li, XJ#. AHI1: linking depression and impaired antiviral immune response. Cell Research, 2022, 0:1-2. (#co-corresponding author)
9. Yang W*, Wang G*, Wang C*, Guo X, Yin P, Gao J, Tu Z, Wang Z, Wu J, Hu X, Li S, Li X-J. Mutant Alphα-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain, J Neurosci. 35: 8345-58, 2015. (co-first author)
10. Yang W, Tu Z, Sun Q, Li X-J. CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases, Front. Mol. Neurosci. 9:30, 2016.
11. Li B*, Zhao H*, Tu ZC*, Yang WL*（co-first author）, Han R, Wang L, Luo XP, Pan MT, Chen XS, Zhang JW, Xu HJ, Guo XY, Yan S, Yin, P, Zhao ZG, Liu JR, Luo YF, Li YF, Yang ZY, Zhang BG, Tan ZQ, Xu H, Jiang TZ, Jiang YH. Li SH, Zhang YQ, Li X-J. CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate Cell Discov 2023 In press.
12. Tu Z*, Yang W*（co-first author）, Yan S*, Yin A, Gao J, Liu X, Zheng Y, Zheng J, Li Z, Yang S, Li, SH, Guo X and Li X-J. Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos. Sci Rep. 7: 42081, 2017.
13. Chen Y*, Zheng Y*, Kang Y*, Yang W*(co-first author) , Niu Y, Guo X, Tu Z, Si C, Wang H, Xing R, Pu X, Yang SH, Li S, Ji W, Li X-J. Functional disruption of the dystrophin gene in Rhesus Monkey Using CRISPR/Cas9. Hum. Mol. Genet. 24, 3764-74, 2015.
14. Yang W, Zhang Y, Yang J, Tan L, Yang K. Potential anti-osteoporosis effect of biodegradable magnesium implanted in STZ-induced diabetic rats. J Biomed Mater Res A. 99, 386-94, 2011.
15. Tu Z, Yang W, Yan S, Guo X, Li X-J. CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases. Mol Neurodegener. 10:35, 2015.
16. Li X-J, Tu Z, Yang W, Li S. CRISPR: Established Editor of Human Embryos? Cell Stem Cell. 21(3):295-296, 2017.
17. Yin P, Guo X, Yang W, Yan S, Yang S, Zhao T, Sun Q, Liu Y, Li S, Li X-J. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathol. 137(6):919-937, 2019.
18. Yin P, Liu Q, Pan Y, Yang W, Yang S, Wei W, Chen X, Hong Y, Bai D, Li X-J, Li S. Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease. EMBO Reports. 21: e49783, 2020.
19. Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, Yang W, Zhao Y, Ouyang Z, Lai C,Yang H, Li L, Liu Q, Shi H, Xu G, Zhao H, Wei H, Pei Z, Li S, Lai L, Li X-J. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. Cell. 173(4):989-1002, 2018.
20. Jing L, Cheng S, Pan Y, Liu Q, Yang W, Li S, Li X-J. Accumulation of Endogenous Mutant Huntingtin in Astrocytes Exacerbates Neuropathology of Huntington Disease in Mice. Mol Neurobiol. 2021.
21. Yang S, Yang HM, Chang RB Yang Y, Yin P, Yang W, Huang SS Geartig, MA, Li SH, Li X-J. MANF regulates hypothalamic control of food intake and body weight. Nature Commun. 18;8(1):579, 2017.
22. Zhao H, Tu ZC, Xu HJ, Yan S, Yan HH, Zheng YH, Yang W, Zheng JH, Li ZJ, Tian R, Lu YM Gao XY, Jiang YH, Li X-J. Zhang YQ. Altered neurogenesis and disrupted expression of synaptic proteins in SHANK3 deficient non-human primate prefrontal cortex. Cell Res. 27(10):1293-1297. 2017.
23. Niu Y, Guo X, Chen Y, Wang C, Gao J, Yang W, Kang Y, Si W, Wang H, Yang SH, Li S, Ji W, Li X-J. Early Parkinson's disease symptoms in α-synuclein transgenic monkeys. Hum. Mol. Genet. 24, 2308-17, 2015.
24. Chen X, Sun Y, Chen L, Chen XS, Pan M, Zhang Y, Wang Q, Yang W, Yin P, He D, Guo X, Yang S, Zeng Y, Yan S, Li XJ, Li S. Differential expression and roles of Huntingtin and Huntingtin-associated protein 1 in the mouse and primate brains. Cell Mol Life Sci. 2022 Oct 17;79(11):554. doi: 10.1007/s00018-022-04577-8. PMID: 36251080.
25. Chen X, Xin N, Pan Y, Zhu L, Yin P, Liu Q, Yang W, Xu X, Li S, Li XJ. Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response. Front Cell Neurosci. 2020 Jun 4;14:125. doi: 10.3389/fncel.2020.00125. PMID: 32581713; PMCID: PMC7289054.
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