当前位置: X-MOL首页全球导师 国内导师 › 赵元

个人简介

主要科研项目 1.不同种属动物小肠上皮细胞与β-Conglycinin抗原表位结合受体表达与分布的比较研究(31572439),国家自然科学基金面上项目, 2016-2019,主持 2.果寡糖缓解大豆抗原诱导仔猪致敏反应及相关机制的研究(20160101348JC),吉林省自然科学基金项目,2016-2018,主持 3.高效减氮排放型猪饲粮配制关键技术的研究(20180201018NY),吉林省重点科技研发项目,2018-2020,主持 主要科研成果 1.大豆抗原蛋白β-Conglycinin及其抗酶解肽对仔猪肠上皮细胞屏障功能损伤的研究 (31101719),国家自然基金青年基金, 2015,主持; 2. 大豆抗原蛋白Glycinin对仔猪肠上皮细胞机械屏障功能损伤的研究(201201098),吉林省科技厅青年科学基金, 2012-2015,主持; 3.饲料营养价值与畜禽饲养标准研究与应用(200903006),国家公益性行业(农业)科研专项子课题,重点项目, 2014,排名第9; 4.蛋白质糖基化去除大豆抗原蛋白免疫原性及相关机制,国家自然科学基金, 2014年,排名第2; 5.发酵法钝化大豆抗营养因子的研究,吉林省科技厅青年科学基金, 2014,排名第4; 6.大豆抗原蛋白Glycinin在鲤鱼不同发育时期抗营养作用的比较研究,吉林省科技厅项目, 2014,排名第4; 7.钙对猪肉品质调控机制的研究,吉林省科技厅项目,2012,排名第6; 8.大豆主要抗原蛋白对不同食性鱼类抗营养作用的比较研究,吉林省教育厅项目,2012,排名第3; 9.仔猪胃肠组织对日粮抗原β-Conglycinin敏感性的研究(201044),吉林省教育厅重点项目,2012,主持; 10.大豆抗原β-Conglycinin酶解肽对仔猪小肠上皮细胞紧密连接表达影响的研究,吉林省教育厅项目(2015198), 2015-2016,主持; 专利 (1)大豆凝集素提取纯化方法,ZL2011101149043,发明专利 (2)兔小肠上皮细胞系及其制备方法, ZL201110114926.X,2012,发明专利 获奖信息 1.大豆凝集素对消化道屏障功能影响的比较研究,吉林省自然科学学术成果奖,一等奖,2014,排名第8; 2.猪消化道对大豆抗营养因子敏感性的比较研究,吉林省自然科学学术成果奖,三等奖,2014,排名第1; 3.大豆主要抗营养因子的抗营养机制及钝化机理的研究,吉林省科学技术进步一等奖(20092009J10019),2009,排名第8; 4.大豆主要抗营养因子抗营养机制研究,吉林省自然科学学术成果奖,一等奖,2011,排名第3; 5. 仔猪饲粮蛋白原与肠道健康耦合机制的研究, 吉林省科学技术进步二等奖,2017,排名第2;

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(1)Yuan Zhao, Dandan Liu, Rui Han, Xiaodong Zhang, Shiyao Zhang,Guixin Qin*。Soybean allergen glycinin induced the destruction of the mechanical barrier function in IPEC-J2. Food and Agricultural Immunology. 2015, 26(4): 601–609. (2) Yuan Zhao, Bing Zhang, Guixin Qin*, Tao Wang, Nan Bao, Xiaodong Zhang. Gastrointestinal Tissue Distribution of β-Conglycinin in Pigs at Different Growth Stages. Journal of Food and Nutrition Research. 2015, 3( 6):379-383. (3)Yuan Zhao, Guixin Qin, Rui Han, Jun Wang, Xiaodong Zhang,Dandan Liu. β-Conglycinin Reduces the Tight Junction Occludin and ZO-1 Expression in IPEC-J2. Int. J. Mol. Sci. 2014, 15, 1915-1926. (4)Yuan Zhao, Bing Zhang, Guixin Qin*, Tao Wang, Jun Wang,Rui Han. Distribution of glycinin in the gastrointestinal tissue of pigs at different growth stages. Food and Agricultural Immunology. 2013,24(3):371-378. (5)Yuan Zhao, Guixin Qin*, Zewei Sun, Dongsheng Che, Nan Bao, Xiaodong Zhang. Effects of Soybean Agglutinin on Intestinal Barrier Permeability and Tight Junction Protein Expression in Weaned Piglets. Int. J. Mol. Sci. 2011, 12, 8502-8512. (6)Zhao Yuan, Qin Guixin, Sun Zewei, Zhang Bing, Wang Tao. Effects of glycinin and β-conglycinin on enterocyte, apoptosis, proliferation and migration of piglets. Food and Agricultural Immunology. 2010, 21 (3), 209-218. (7)Zhao Yuan, Qin Guixin, Sun Zewei, Zhang Bing, Wang Tao. Stability and Immunoreactivity of glycinin and β-conglycinin to hydrolysis in vitro. Food and Agricultural Immunology. 2010, 21 (3), 253-263. (8)Zhao Yuan, Qin Guixin, Sun Zewei, Zhang Xiaodong, Bao Nan, Wang Tao, Zhang Bing, Zhang Bolin, Zhu Dan, Sun Ling. Disappearance of immunoreactive glycinin and β-conglycinin in the digestive tract of piglets. Archives Animal Nutrition. 2008, 62 (4), 322-330. (8)Zhao Yuan, Qin Guixin, Sun Zewei, Zhang Xiaodong, Bao Nan, Wang Tao, Zhang Bing, Zhang Bolin, Zhu Dan, Sun Ling. Disappearance of immunoreactive glycinin and β-conglycinin in the digestive tract of piglets. Archives Animal Nutrition. 2008, 62 (4), 322-330. (9) Zhang shiyao , Cao Kefei, Liu Dandan, Naren Gaowa, Bao Nan, Zhao Yuan(*). Development of dcELISA Method for Rapid Detection of β-conglycinin in Soybean. International Journal of Food Engineering. 2016, 12 (5): . DOI: https://doi.org/10.1515/ijfe-2015-0359 (10)Zhao Yuan, Zhang shiyao, Naren Gaowa,Qin Guixin. The immunoreactive protein was produced during absorption of glycinin or its hydrolysate in IPEC-J2. International Journal of Food Engineering. 2017, 13 (9): . DOI: https://doi.org/10.1515/ijfe-2016-0441 (11)Zhao Yuan, Liu Dandan, Zhang shiyao, Pan Li, Qin Guixin. Different damage to the mechanical barrier function of IPEC-J2 induced by soybean allergen β-conglycinin hydrolyzed peptides. International Journal of Food Engineering. 2017, 13 (10): . DOI: https://doi.org/10.1515/ijfe-2016-0370

推荐链接
down
wechat
bug