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个人简介

刘静波,吉林大学唐敖庆特聘教授,工学博士,博士生导师。 先后承担“十三五”国家重点研发计划项目,自然科学基金面上项目等多项国家及省部级项目,累计科研经费超过4000万元。发表论文200余篇,其中SCI/EI收录90余篇;申请国家发明专利150余件,获得授权36件,被认定吉林省科学技术成果6项;国家精品课《食品营养学》课程负责人,吉林省《食品营养学》优秀教学团队负责人。获“全军优秀教师”、“吉林大学名师”、“吉林大学师德标兵”、“吉林省拔尖创新人才”等荣誉称号;受邀担任《Journal of Agricultural and Food Chemistry》、《Food Chemistry》、《Food & Function》、《食品科学》等国内外知名期刊审稿专家。 长期从事方便营养型蛋制品绿色加工关键技术研究及开发,蛋粉加工适用性改进及综合利用,食源性生物活性肽的开发、完整吸收及可控递送机制,食源性生物活性肽的结构鉴定与活性表征,活性肽的一、二级结构与生物活性关系,活性肽的结构与小肠完整吸收关系及吸收机制,功能型蛋粉的分离及精准营养搭配,长白山特色资源综合利用与开发等方面的研究工作。 从1984年8月至今,先后在解放军兽医大学、农牧大学、军需大学和吉林大学承担教学工作,荣获个人三等功1次,集体二等功1次,被授予“全军优秀教师”、“吉林大学教学名师”、“第二批吉林省拔尖创新人才”荣誉称号;担任国家精品课《食品营养学》课程负责人,吉林省《食品营养学》优秀教学团队负责人;承担国家级、省级有关食品科学与工程专业教学研究课题6项;获得教学成果奖6项,其中省级以上教学成果奖3项;公开发表教学研究论文20余篇;出版教材专著30余部,其中第一主编公开出版教育部食品科学与工程专业教学指导分委员会推荐特色教材《功能食品学》,成功入选“十二五”普通高等教育本科国家级规划教材、被评为吉林省省级优秀教材二等奖、吉林大学优秀教材一等奖;并列主编公开出版教育部轻工与食品教学指导委员会推荐特色教材《食品无菌加工技术与设备》荣获中国石油和化学工业协会优秀教材二等奖。 教育经历 1999.09 - 2004.06,吉林大学,农业机械化工程,博士 1980.09 - 1984.06,吉林农业大学,动物营养学,学士 工作经历: 2014.09-至今 吉林大学新农村发展研究院 常务副院长 2004.09-2019.09 吉林大学军需科技学院 院长(教授) 2003.09-2004.08 中国人民解放军军需大学 教授 1999.09-2003.08 中国人民解放军军需大学 副教授 1987.07-1999.08 中国人民解放军农牧大学 讲师/副教授 1984.08-1987.06 中国人民解放军兽医大学 助教 科研项目 类型 项目名称 立项编号 经费 (万元) 开始时间 结束时间 项目性质 及来源 基础研究 肠细胞ASBT介导的脱氧胆酸偶联壳聚糖-蛋清源活性肽纳米颗粒胞吞作用机制 32072238 58 2021.01 2024.12 面上项目 自然科学基金委 共性关键技术研究 方便营养型蛋制品绿色加工关键技术研究及开发 2018YFD0400300 2660 2018.07 2020.12 十三五国家重点研发计划项目 科技部 基础研究 基于Caco-2细胞膜和大鼠外翻肠囊模型的蛋清源活性寡肽完整吸收途径及机制研究 31771985 60 2018.01 2021.12 面上项目 自然科学基金委 基础研究 基于Nrf2/ARE信号通路的蛋清源小肽协同抗氧化作用机制研究 31471597 92 2015.01 2018.12 面上项目 自然科学基金委 基础研究 基于Caco-2细胞模型的蛋清肽结构与完整吸收关系研究 31271907 86 2013.01 2016.12 面上项目 自然科学基金委 共性关键技术 食源性功能肽生物制备技术研究 2012BAD33B03 731 2012.01 2015.12 国家“十二五”科技支撑 科技部 申请国家发明专利: 申请国家发明专利150余件,以第一发明人授权专利36件。 序号 专利名称 申请号 1 一种Keap1   Kelch区多位点分子对接筛选食源性抗氧化寡肽的方法 CN201611081486.1 2 一种松籽油皮诺敛酸微胶囊及其制备方法 CN201310194780.3 3 一种纯天然小叶女贞果花青素的制备方法 CN201510412024.2 4 一种苯丙氨酸鳌合钙粉及加工方法 CN201410177654.1 5 一种含有大豆多肽的姜汁饼干及其生产工艺 CN201410525896.5 6 一种松仁富硒奶茶及其制备工艺 CN201410235449.6 7 一种蛋氨酸鳌合钙片及加工方法 CN201410177591.X 8 一种含蛋清蛋白肽的肠内营养制剂及其制备方法 CN201310215824.6 9 一种赖氨酸鳌合钙粉及加工方法 CN201410177629.3 10 一种载亚油酸的大豆分离蛋白/壳聚糖复合微胶囊及其制备方法 CN201310260475.X 11 一种含卵磷脂的肠内营养乳剂及其制备方法 CN201310332503.4 12 一种人参方便汤料及制备工艺 CN201410081819.5 13 一种人参滋补挤压膨化食品及其制作工艺 CN201410170742.9 14 含鸡蛋壳膜水解液和杜香水馏物的护手霜及其生产方法 CN201110005168.8 15 一种含大豆寡肽的营养流食及其制备方法 CN201310327448.X 16 松仁露果粒饮料及其制备方法 CN201310327447.5 17 一种复合型两亲性芯材微胶囊冲剂及其制备方法 CN201310228666.8 18 检测蛋黄油中二十二碳六烯酸含量的方法 CN201110433100.X 19 一种豆制饮品及其制备方法 CN201310282279.2 20 一种含大豆寡肽的老年营养粉及其制备方法 CN201310282298.5 21 一种松子营养休闲食品及其制备方法 CN201310282258.0 22 一种液态乳品复合型增稠剂及其制备方法 CN201310228654.5 23 便利型抗氧化肽香橙果冻饮的加工工艺 CN201210548416.8 24 一种速溶鸡蛋泡腾片 CN201110093225.2 25 一种含咸蛋清蛋白多肽的肠内营养制剂及其制备方法 CN201110365801.4 26 胶原蛋白悬浮果粒饮的加工及配方 CN201110255434.2 27 长白山杜香杀菌护肤洗手液及其制备方法 CN201110067291.2 28 双蛋白胶原肽饮料的加工工艺及配方 CN201110111560.0 29 一种禽蛋或其制品中胆固醇含量的检测方法 CN201110365793.3 30 利用富硅植物制备正硅酸提取液和硅补充剂的方法 CN201110207493.2 31 玉米花丝饮品及其制备方法 CN200810050578.2 32 膳食纤维玉米片及其制备方法 CN200810050634.2 33 玉米花丝软胶囊及其制备方法 CN200810050635.7 34 蛋清高F值寡肽含片及其制备方法 CN200810050557.0 35 笃斯越桔花青素及其分离纯化方法 CN200810050659.2 36 一种以废弃香菇培养基为原料提取香菇多糖的方法 CN200810050633.8

研究领域

营养与功能食品、蛋品精深加工与副产物综合利用等。

近期论文

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Zhiyang Du, Jingbo Liu, Hui Zhang, Yuelin Chen, Xinling Wu, Yanqun Zhang, Xinyu Li, Ting Zhang, Hang Xiao, and Boqun Liu (2020). L-Arginine/L-Lysine functionalized chitosan-casein core-shell and pH- responsive nanoparticles: fabrication, characterization and bioavailability enhancement of hydrophobic and hydrophilic bioactive compounds[J]. Food & Function, 11(5): 4638-4647. (Ⅰ区) Xuanting Liu, Wenqi Zhang, Jingbo Liu, Robin Pearce, Yang Zhang, Kangxin Zhang, Qingyang Ruan, Yiding Yu, Boqun Liu (2020). Mg2+ inhibits heat-induced aggregation of BSA: the mechanism and its binding site[J]. Food Hydrocolloids, 01, 105450. (Ⅰ区) Xuanting Liu, Jingbo Liu, Wenqi Zhang, Robin Pearce, Meiru Chen, Jiajian Tang, Ting Zhang, Boqun Liu (2020). Effect of the Degree of Glycation on the Stability and Aggregation of Bovine Serum Albumin[J]. Food Hydrocolloids, 106, 105892. (Ⅰ区) Zhiyang Du, Jingbo Liu, Hui Zhang, Xinling Wu, Biying Zhang, Yuelin Chen, Boqun Liu, Long Ding, Hang Xiao, and Ting Zhang (2019). N-acetyl-L-cysteine / L-cysteine-functionalized chitosan-beta-lactoglobulin self-assembly nanoparticles: a promising way for oral delivery of hydrophilic and hydrophobic bioactive compounds[J]. Journal of Agricultural and Food Chemistry, 67(45): 12511-12519. (Ⅰ区) Zhiyang Du, Jingbo Liu, Deju Zhang, Long Ding, Yizhen Wang, Dawei Tan, Ting Zhang (2019). Individual and Synergistic Antioxidant Effects of Dipeptides in In Vitro Antioxidant Evaluation Systems[J]. International Journal of Peptide Research and Therapeutics, 25(1): 391-399. (IV区) Xuanting Liu, Jingbo Liu, Wenqi Zhang, Shuo Han, Ting Zhang, Boqun Liu (2019). Electron beam irradiation-induced structural changes increase the antioxidant activities of egg white protein[J]. LWT - Food Science and Technology, 111, 846-852. (ⅠI区) Du Zhiyang, Liu Jingbo, Zhang Ting, Yu Yiding, Zhang Yan, Zhai Jinxing, Huang Haitao, Wei Shibiao, Ding Long, Liu Boqun (2019). A study on the preparation of chitosan-tripolyphosphate nanoparticles and its entrapment mechanism for egg white derived peptides.[J]. Food chemistry, 286.(Ⅰ区) Du Zhiyang; Liu Jingbo; Zhai Jinxing; Huang Haitao; Wei Shibiao; Zhang Ting; Ding Long (2019). Fabrication of N-acetyl-L-cysteine and L-cystine functionalized chitosancasein nanohydrogels for entrapment of hydrophilic and hydrophobic bioactive compounds.[J]. Food Hydrocolloids, 96(Ⅰ区) Wang L , Ding L , Xue C , et al. (2018) Corn gluten hydrolysate regulates the expressions of antioxidant defense and ROS metabolism relevant genes in H2O2 -induced HepG2 cells[J]. Journal of Functional Foods, 42:362-370.(Ⅰ区) Ding L , Wang L , Zhang T , et al. (2018) Hydrolysis and transepithelial transport of two corn gluten derived bioactive peptides in human Caco-2 cell monolayers[J]. Food Research International, S0963996917309444.(Ⅰ区) Yali Yu, Yao Wang, Ying Wang, Dingbo Lin, Xinxin Li, Jingbo Liu (2018). Preparation and Properties of Granular Cold-Water-Soluble Maize Starch by Ultrasonic-Assisted Alcoholic-Alkaline Treatment[J].Starch Biosynthesis, Nutrition, Biomedical. 70, 11-12.(Ⅱ区) Ding L, Wang L, Yu Z, et al. (2017) Importance of Terminal Amino Acid Residues to the Transport of Oligopeptides across the Caco-2 Cell Monolayer [J]. Journal of Agricultural & Food Chemistry, 65(35):7705.(Ⅰ区) Liu D, Zhang T, Chen Z, et al. (2017) The beneficial effect of ginsenosides extracted by pulsed electric field against hydrogen peroxide-induced oxidative stress in HEK-293 cells[J]. Journal of ginseng research, 41(2): 169-179.(Ⅰ区) Zhang D, Wang Y, Xu M, et al. (2017) Antioxidant Synergetic Effect Between the Peptides Derived from the Egg White Pentapeptide Trp-Asn-Trp-Ala-Asp[J]. International Journal of Peptide Research & Therapeutics, (8):1-10.(IV区) Li L, Liu J, Nie S, et al. (2017) Direct inhibition of Keap1–Nrf2 interaction by egg-derived peptides DKK and DDW revealed by molecular docking and fluorescence polarization[J]. Rsc Advances, 7(56):34963-34971.(Ⅰ区) Liying Wang, Long Ding, Zhipeng Yu, Ting Zhang, Shuang Ma, Jingbo Liu. (2016). Intracellular ROS scavenging and antioxidant enzyme regulating capacities of corn gluten meal-derived antioxidant peptides in HepG2 cells. Food Research International.2016(Ⅰ区) Zhipeng Yu, Wenzhu Zhao, Long Ding, Yaqi Wang, Feng Chen, Jingbo Liu(2016). Short- and Long-term Antihypertensive Effect of egg protein-derived Peptide QIGLF.Journal of The Science of Food and Agriculture.(Ⅰ区) Long Ding, Liying Wang, Zhipeng Yu, Ting Zhang, Jingbo Liu (2016). Digestionand absorption of an egg white ACE-inhibitory peptide in human intestinal Caco-2 cell monolayers. International Journal of Food Sciences and Nutrition.(Ⅰ区) Yu Zhipeng, Zhao Wenzhu, Ding Long, Yu Yiding, Liu Jingbo (2016). Anxioly tic eects of ACE inhibitory peptides on the behavior of rats in an elevated plus-maze. Food & Function.(Ⅰ区) Ding L, Wang L, Zhang Y, et al. (2015). Transport of Antihypertensive Peptide RVPSL, Ovotransferrin 328-332, in Human Intestinal Caco-2 Cell Monolayers [J]. Journal of Agricultural & Food Chemistry, 63(37):8143.(Ⅰ区) Pan F, Han L, Zhang Y, et al. (2015). Optimization of Caco-2 and HT29 co-culture in vitro cell models for permeability studies [J]. International Journal of Food Sciences & Nutrition, 66(6):680.(Ⅰ区) Liu J, Jin Y, Lin S, et al. (2015). Purification and identification of novel antioxidant peptides from egg white protein and their antioxidant activities[J]. Food Chemistry, 175(9):258.(Ⅰ区) Ting Zhang, Shaoping Nie, Boqun Liu, Yiding Yu, Yan Zhang, Jingbo Liu (2015). Activity prediction and molecular mechanism of bovine blood derived angiotensin I-converting enzyme inhibitory peptides. PloS one, 10 (3): e0119598,.(III区) Liying Wang, Long Ding, Ying Wang, Yan Zhang, Jingbo Liu(2015). Isolation and Characterisation of in Vitro and Cellular Free Radical Scavenging Peptides from Corn Peptide Fractions. Molecules, 20(2): 3221-3237.(III区) Jingbo Liu, Zhifei Chen, Jing He, Yan Zhang, Ting Zhang and Yiqun Jiang (2014). Anti-oxidative and Anti-apoptosis Effects of Egg White Peptide, Trp-Asn-Trp-Ala-Asp, Against H2O2-Induced Oxidative Stress in Human Embryonic Kidney 293 Cells. Food & Function, 5,3179-3188.(Ⅰ区) Long Ding, Yan Zhang, Yiqun Jiang, Liying Wang, Boqun Liu, and Jingbo Liu(2014). Transport of Egg White ACE-Inhibitory Peptide, Gln-Ile-Gly-Leu-Phe, in Human Intestinal Caco‑2 Cell Monolayers with Cytoprotective Efffect, Journal of Agricultural and Food Chemsitry, 62, 3177-3182.(Ⅰ区) Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Feng Chen, Jingbo Liu(2014). Antihypertensive Effect of Angiotensin-Converting Enzyme Inhibitory Peptide RVPSL on Spontaneously Hypertensive Rats by Regulating Gene Expression of the Renin-Angiotensin System, Journal of Agricultural and Food Chemistry, 62(4): 912-917.(Ⅰ区) Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Feng Chenb and Jingbo Liu (2014). Application and bioactive properties of proteins and peptides derived fromhen eggs: opportunities and challenges. J Sci Food Agric, 94: 2839-2845.(Ⅰ区) Zhipeng Yu, Yongguang Yin, Wenzhu Zhao, Jingbo Liu, Feng Chen (2012). “Anti-diabetic activity peptides from albumin against a-glucosidase and a-amylase”. Food Chemistry:135, 2078–2085.(Ⅰ区) Zhipeng Yu, Boqun Liu, Wenzhu Zhao, Yongguang Yin, Jingbo Liu(2012). Feng Chen .Primary and secondary structure of novel ACE-inhibitory peptides from egg white protein.Food emistry:133: 315-322.(Ⅰ区) Zhao W, Yin Y, Yu Z, et al. (2012). Comparison of anti-diabetic effects of polysaccharides from corn silk on normal and hyperglycemia rats.[J]. International Journal of Biological Macromolecules, 50(4):1133-1137.(Ⅰ区) Songyi Lina, LiyanWang, Gregory Jones, Hung Trang, Yongguang Yin, Jingbo Liu(2012). Optimized extraction of calcium malate from eggshell treated by PEF and an absorption assessment in vitro, International Journal of Biological Macromolecules:50:1327–1333.(Ⅰ区) Songyi Lin, Yang Guo, Qi You, Yongguang Yin and Jingbo Liu(2012). Preparation of antioxidant peptide from egg white protein and improvement of its activities assisted by high-intensity pulsed electric field, Journal of the Science of Food and Agriculture:;92: 1554–1561.(Ⅰ区) Liu M. (2012). Optimization of extraction parameters for protein from beer waste brewing yeast treated by pulsed electric fields (PEF) [J]. African Journal of Microbiology Research, 6(22):4739-4746.(Ⅰ区) Wang J, Wang K, Lin S, et al. (2012) Improvement of antioxidant activity of peptides with molecular weights ranging from 1 to 10 kDa by PEF technology.[J]. International Journal of Biological Macromolecules, 51(3):244-249.(Ⅰ区) Wang K, Wang J, Zhao P, et al. (2012) Optimized PEF treatment for antioxidant polypeptides with MW 10-30 kDa and preliminary analysis of structure change [J]. International Journal of Biological Macromolecules, 51(5):819-825.(Ⅰ区) Zhuang, Hong, Zhang, Tiehua, Liu, Jingbo, Yuan, Yuan(2012). Detection of acrylamide content in traditional Chinese food by high-performance liquid chromatography tandem mass spectrometry method, CYTA-JOURNAL OF FOOD: 10(1): 36-41.(Ⅳ区) Zhang M, Ping H, Cao X, et al. (2012). Rapid determination of melamine in milk using water-soluble CdTe quantum dots as fluorescence probes [J]. Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 29(3):333-44.(Ⅳ区) Yu, Z. P., W. Z. Zhao, et al. (2011). QIGLF, a novel angiotensin I-converting enzyme-inhibitory peptide from egg white protein. Journal of the Science of Food and Agriculture 91(5): 921-926.(Ⅲ区) Zhao, W. Z., Z. P. Yu, et al. (2011). Optimized extraction of polysaccharides from corn silk by pulsed electric field and response surface quadratic design. Journal of the Science of Food and Agriculture 91(12): 2201-2209.(Ⅲ区) Yu, Z., Y. Yin, et al. (2011). Characterization of ACE-Inhibitory Peptide Associated with Antioxidant and Anticoagulation Properties. Journal of Food Science 76(8): C1149-C1155.(Ⅰ区) Liu, J., C. N. Wang, et al. (2011). The antioxidant and free-radical scavenging activities of extract and fractions from corn silk (Zea mays L.) and related flavone glycosides. Food Chemistry 126(1): 261-269.(Ⅰ区) Lu, J., S. Guan, et al. (2011). In Vivo Genotoxicity Evaluation of Crude Extract from Ledum palustre and Protective Effects on Cyclophosphamide-Induced Genotoxicity in Mice. Latin American Journal of Pharmacy 30(1): 112-118.(Ⅳ区) Niu, X. D., H. S. Wang, et al. (2011). Efficient green-phosphorescent light-emitting diodes based on polymeric binary-host systems. Journal of Luminescence 131(12): 2589-2592.(Ⅱ区) Wang, C., T. Zhang, et al. (2011). “Subchronic toxicity study of corn silk with rats.” Journal of Ethnopharmacology 137(1): 36-43.(Ⅲ区) Jun Liu, Songyi Lin, Zuozhao Wang, Cuina Wang, Erlei Wang, Yan Zhang, Jingbo Liu (2011).Supercritical fluid extraction of flavonoids from Maydis stigma and its nitrite-scavenging ability.Food and Bioproducts Processing, 89(4):333-339.(Ⅲ区) Zhang, T. H., J. Zheng, et al. (2011). Purification Technology and Antimicrobial Activity Analysis of Antimicrobial Peptide from Ovotransferrin. Chemical Research in Chinese Universities 27(3): 361-365.(Ⅳ区) Shi, X. L., Y. R. Jin, et al. (2011). Matrix solid phase dispersion extraction of ginsenosides in the leaves of Panax ginseng CM Mey. Food Chemistry 129(3): 1253-1257.(Ⅰ区) Yu Z, Yin Y, Zhao W, et al. (2011). Novel peptides derived from egg white protein inhibiting alpha-glucosidase[J]. Food Chemistry, 129(4):1376-1382.(I区) Guan, S., J. Lu, et al. (2011). Florfenicol impairs the immune responses to vaccination against foot-and-mouth disease in mice. Immunopharmacology and Immunotoxicology 33(4): 609-613.(Ⅳ区) Yuan, Y., H. Zhuang, et al. (2010). Patulin content in apple products marketed in Northeast China. Food Control 21(11): 1488-1491.(Ⅱ区) Liu, J. B., Z. P. Yu, et al. (2010). Isolation and identification of angiotensin-converting enzyme inhibitory peptides from egg white protein hydrolysates. Food Chemistry 122(4): 1159-1163.(Ⅰ区) Liu, J. B., Z. P. Yu, et al. (2010). Liquid Chromatographic Assay of Peptides Activity with Inhibiting Angiotensin Converting Enzyme. Chemical Research in Chinese Universities 26(5): 712-716.(Ⅳ区) Niu X, Liu J, Xie Z. (2010). Efficient white polymer light-emitting diodes based on the control of a emissive polymer morphology through solvent processing[J]. Organic Electronics, 11(7):1273-1276.(Ⅱ区) Yu L, Guo N, Yang Y, et al.(2010). Microarray analysis of p-anisaldehyde-induced transcriptome of Saccharomyces cerevisiae.[J]. Journal of Industrial Microbiology & Biotechnology, 37(3):313-322.(Ⅱ区) 出版著作: 论著题目 出版单位 出版时间 《功能食品学》 化学工业出版社(第一主编) 2008.03 《食品无菌加工技术与设备》 化学工业出版社(第二主编) 2006.01 《蛋与蛋制品加工学》 中国农业出版社(副主编) 2007.01 《畜产食品工艺学》 中国农业出版社(副主编) 2008.01 《食品安全与选购》 化学工业出版社(第一主编) 2006.09 《大豆食品工艺学》 化学工业出版社(第二主编) 2006.01 《蛋品科学技术》 化学工业出版社(副主编) 2006.03 《蛋制品生产技术》 吉林科学技术出版社(副主编) 2008.01 营养师系列丛书 —《青少年营养配餐》 化学工业出版社(第一主编) 2006.09 营养师系列丛书 —《婴幼儿营养配餐》 化学工业出版社(第一主编) 2006.09 营养师系列丛书 —《中老年人营养配餐》 化学工业出版社(第一主编) 2006.09 营养师系列丛书 —《上班族营养配餐》 化学工业出版社(第一主编) 2006.09 营养师系列丛书 —《孕产妇营养配餐》 化学工业出版社(第一主编) 2006.09

学术兼职

教育部高等学校2018-2022食品科学与工程类专业教学指导委员会副主任、中国工程教育专业认证协会认证结论审议委员会委员、食品类专业认证委员会成员、亚洲蛋品协会副会长、国家蛋品工程技术研究中心专家组成员、吉林省功能食品工程研究中心主任、吉林省营养与功能食品重点实验室主任等。

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