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个人简介

教育经历 1993/9 – 1997/6,兰州大学,天然有机专业,博士学位 1987/9 – 1990/6,广东工业大学,精细化工专业,硕士学位 1981/9 – 1985/6,广东工业大学(原广东工学院),分析化学专业,学士学位 工作经历 2014/2– 至今,五邑大学党委书记 2010/2– 2014/5,五邑大学校长 1999/12 – 至今,广东工业大学,轻工化工学院,教授 1999年,美国圣路易士大学访问学者,从事抗癌中药开发研究 1995/12 – 1999/12,广东工业大学,轻工化工学院,副教授 1992/12 – 1995/12,广东工业大学,轻工化工学院,讲师 1985/7 – 1987/8,广东工业大学,轻工化工学院,任教

研究领域

天然药物化学,有机合成化学

近期论文

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[1]Li D. L.; Du Z. Y.; Li C. Y.; Liu Y.; Goodin S.; Huang H. R.; He Y.; Zhang Y.; Wang H. Q.; Zheng X*; Zhang K.*. Potent inhibitory effect of terpenoids from Acanthopanax trifoliatus on growth of PC-3 prostate cancer cells in vitro and in vivo is associated with suppression of NF-κB and STAT3 signalling [J]. Journal of Functional Foods, 2015, 15: 274-283. [2]Pan-Pan Wu, Kun Zhang*, Yu-Jing Lu, Ping He, Su-Qing Zhao*. In vitro and in vivo evaluation of the antidiabetic activity of ursolic acid derivatives [J]. European Journal of Medicinal Chemistry, 2014, 80: 502-508. [3]Pan-Pan Wu, Ping He, Kun Zhang*, Su-Qing Zhao*, Yu-Jing Lu, Tian-Ming Huang. Anti-diabetic effects of ursolic acid derivatives on Caco-2 cells and its alleviating role in streptozocin-induced type 2 diabetic rats [J]. Molecules, 2014, 19: 12559-12576. [4] Huarong Huang, Yan He, Xiao-Xing Cui, Susan Goodin, Hong Wang, Zhi Yun Du, Dongli Li, Kun Zhang, Ah-Ng Tony Kong, Robert S. DiPaola, Chung S. Yang, Allan H. Conney, Xi Zheng. Potent inhibitory effect of δ-tocopherol on prostate cancer cells cultured in vitro and grown as xenograft tumors in vivo. J Agric Food Chem. 2014, 62(44): 10752-10758. [5] Haoliang Fu, Hu Chang, Jie Shen, Lin Yu, Bo Qin,* Kun Zhang* and Huaqiang Zeng*,An unusual macrocyclization reagent for highly selective one-pot synthesis of strained macrocyclic aromatic hexamers, Chem. Commun., 50, 3582-3584, 2014. [6]Yongfu Jiang, Zhiyun Du*, Guihua Xue, Qian Chen, Yujing Lu, Xi Zheng, Allan H. Conney, Kun Zhang*. Synthesis and biological evaluation of unsymmetrical curcumin analogues as tyrosinase inhibitors, Molecules, 18(4):3948-61, 2013. [7] Zhou DY, Zhang K, Conney AH, Ding N, Cui XX, Wang H, Verano M, Zhao SQ, Fan YX, Zheng X*, Du ZY*. Synthesis and evaluation of curcumin-related compounds containing benzyl piperidone for their effects on human cancer cells. Chem Pharm Bull (Tokyo). 61(11):1149-55, 2013. [8]Xingchuan Wei , Zhi-Yun Du , Xi Zheng, Xiao-Xing Cui, Allan H. Conney**, Kun Zhang*. Synthesis and evaluation of curcumin-related compounds for anticancer activity. Eur J Med Chem. 2012,53: 235-245. [9] Xingchuan Wei, Zhi-Yun DU, Xiao-Xing Cui, Michael Verano, Rong Qing Mo, Zhi Kai Tang, Allan H Conney, Xi Zheng*, Kun Zhang*. Effects of cyclohexanone analogues of curcumin on growth, apoptosis and NF-κB activity in PC-3 human prostate cancer cells. Oncol Lett 4(2):279-284(2012) [10] Zhi Yun DU, Yong Fu JIANG, Zhi Kai TANG, Rong Qing MO, Gui Hua Xue, Yu Jing LU, Xi ZHENG, Chang Zhi DONG*, ang Kun ZHANG*. Antioxidation and Tyroinase Inhibition of Polypgenolic Curcumin Analogs. Biosci. Biotechnol. Biochem. 2011,75(12): 2351-8.

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