朱之光 - 中国科学院天津工业生物技术研究所 -

个人简介

1、教育经历 2003.9-2007.6，华中科技大学，生物技术，学士 2007.8-2009.5，弗吉尼亚理工大学，生物系统工程，硕士 2009.8-2013.5，弗吉尼亚理工大学，生物系统工程，博士 2、工作经历 2013.7-2016.6，Cell-Free Bioinnovations Inc.，首席技术官 2016.7-至今，中国科学院天津工业生物技术研究所，研究员 2、专著朱之光，张以恒. 2017. 生物制氢. 中国生物产业发展报告2016. 化学工业出版社，北京，中国. ISBN 978-7-122-29797-6, pp 133-139 Zhu ZG, Zhang Y-HP. 2014. Chapter 4. Chemical Biotechnology of in vitro Biosystems for Biomanufacturing. Chemical Promoted Biotechnology and Bioengineering. RSC Green Chemistry Series, RSC Publishing, UK. ISBN:9781849738101. pp 98-121 　 3、专利朱之光；张以恒；宋海燕；马春玲. 一种酶电极、生物传感器及其制备方法和用途 201811109488.6 Zhang Y-H.Percival, Zhu Zhiguang. A high-power and high-energy-density sugar biobattery through an in vitro synthetic enzymatic pathway. U.S. Patent PCT/US14/41103 朱之光；吴晓亮；张以恒；马晖. 可瞬时充电的酶燃料电池 CN105932307A 朱之光；张以恒；马晖；吴晓亮. 体外生物燃料电池嵌入式供电系统 CN105914387A 承担科研项目情况：国家自然科学基金青年项目、面上项目、中科院重点部署项目获奖及荣誉： 2017 中科院北京分院启明星复合型人才 2013 弗吉尼亚理工大学生物系统工程系杰出博士生奖 2012 中国政府国家优秀自费留学生奖学金

研究领域

生物能源与生物化工、生物催化、生物燃料电池、生物电化学合成利用生物工程、合成生物学和生物电化学的方法和原理，研究生物催化与电子传递相关科学问题。通过酶工程改造、人工电子传递链设计、以及生物-纳米介面调控等策略，构建高效、稳定的生物燃料电池、生物电化学合成、生物传感等生物电能应用系统。 (Website: https://www.x-mol.com/groups/zhuzhiguang)

近期论文

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Wu RR,Ma CL,Zhu ZG*.2020.Enzymatic electrosynthesis as an emerging electrochemical synthesis platform.Current Opinion in Electrochemistry 19:1-7 Ma CL,Wu RR,Huang R,Jiang WX,You C,Zhu LL,Zhu ZG*.2019.Directed evolution of a 6-phosphogluconate dehydrogenase for operating an enzymatic fuel cell at lowered anodic pHs.Journal of Electroanalytical Chemistry 851:113444-1113451 Song HY,Ma CL,Liu P,You C,Lin JP,Zhu ZG*.2019.A hybrid CO2 electroreduction system mediated by enzyme-cofactor conjugates coupled with Cu nanoparticle-catalyzed cofactor regeneration.Journal of CO2 Utilization 34:568-575 Xiao XX1,Xia HQ1,Wu RR1,Bai L,Yan L,Magner E,Cosnier S,Lojou E*,Zhu ZG*,Liu AH*.2019.Tackling the challenges of enzymatic(bio)fuel cells.Chemical Reviews 119:9509-9558(1 co-first authors) Wu RR,Ma CL,Yong Y-C,Zhang Y-HP,Zhu ZG*.2019.Composition and distribution of internal resistance in an enzymatic fuel cell and its dependence on cell design and operating conditions.RSC Advances 9:7292-7300 Kang ZP,Zhang Y-HP,Zhu ZG*.2019.A shriveled rectangular carbon tube with the concave surface for high-performance enzymatic glucose/O2 biofuel cells.Biosensors and Bioelectronics 132:76-83 Song HY,Ma CL,Zhou W,You C,Zhang Y-HP,Zhu ZG*.2018.Construction of enzyme-cofactor/mediator conjugates for enhanced in vitro bioelectricity generation.Bioconjugate Chemistry 29:3993-3998 Wu RR,Zhu ZG*.2018.Self-Powered Enzymatic Electrosynthesis of L-3,4-Dihydroxyphenylalanine in a Hybrid Bioelectrochemical System.ACS Sustainable Chemistry Engineering 6:12593-12597 Zhou W,Huang R,Zhu ZG*,Zhang Y-HP*.2018.Coevolution of both Thermostability and Activity of Polyphosphate Glucokinase from Thermobifida fusca YX.Applied&Environmental Microbiology 84:e01224-18 Meng DD,Wei XL,Zhang Y-HP,Zhu ZG,You C*,Ma YH.2018.Stoichiometric Conversion of Cellulosic Biomass by in Vitro Synthetic Enzymatic Biosystems for Biomanufacturing.ACS Catalysis 8:9550-9559 Wu RR,Ma CL,Zhang Y-HP,Zhu ZG*.2018.Complete oxidation of xylose for bioelectricity generation by reconstructing a bacterial xylose utilization pathway in vitro.ChemCatChem 10:2030-2035 Zhu ZG*,You C,Ma YH,Zhang Y-HP.2018.In vitro synthetic enzymatic biosystems at the interface of the food-energy-water nexus:A conceptual framework and recent advances.Process Biochemistry 74:43-49 Zhu ZG*,Ma CL,Zhang Y-HP.2018.Co-utilization of mixed sugars in an enzymatic fuel cell based on an in vitro enzymatic pathway.Electrochimica Acta 263:184-191 You C*,Huang R,Wei XL,Zhu ZG,Zhang Y-HP.2017.Protein engineering of oxidoreductases utilizing nicotinamide-based coenzymes,with applications in synthetic biology.Synthetic and Systems Biotechnology 2:208-218 Zhu ZG,Zhang Y-HP*.2017.In vitro metabolic engineering of bioelectricity generation by the complete oxidation of glucose.Metabolic Engineering 39:110-116 Before TIB Chen H#,Zhu ZG#,Huang R,Zhang Y-HP.2016.Coenzyme engineering of a hyperthermophilic 6-phosphogluconate dehydrogenase from NADP+to NAD+with its application to biobatteries.Scientific Reports 6:36311(#co-first author) Zhu ZG,Zhang Y-HP.2015.Use of nonimmobilized enzymes and mediators achieved high power densities in closed biobatteries.Energy Science&Engineering 3:490-497 Zhu ZG,Tam TK,Sun FF,You C,Zhang Y-HP.2014.A high-energy-density sugar biobattery based on a synthetic enzymatic pathway.Nature Communications 5:3026 Zhu ZG,Tam TK,Zhang Y-HP.2013.Cell-free biosystems in the production of electricity and bioenergy.Advances in Biochemical Engineering/Biotechnology 137:125-152 Zhu ZG,Sun FF,Zhang XZ,Zhang Y-HP.2012.Deep oxidation of glucose in enzymatic fuel cells through a non-natural synthetic enzymatic pathway containing a cascade of two thermostable dehydrogenases.Biosensors and Bioelectronics 36:110-115 Zhu ZG,Wang YR,Minteer SD,Zhang Y-HP.2011.Maltodextrin-powered enzymatic fuel cell through a non-natural enzymatic pathway.Journal of Power Sources 196:7505-7509 Zhu ZG,Sathitsuksanoh N,Vinzant T,Schell DJ,McMillan JD,Zhang Y-HP.2009.Comparative study of corn stover pretreated by dilute acid and cellulose solvent-based lignocellulose fractionation:Enzymatic hydrolysis,supramolecular structure,and substrate accessibility.Biotechnology and Bioengineering 103:715-724 Zhu ZG,Sathitsuksanoh N,Zhang Y-HP.2009.Direct quantitative determination of adsorbed cellulase on lignocellulosic biomass with its application to study cellulase desorption for potential recycling.Analyst 134:2267-2272