个人简介
梅茜,研究员。先后在东南大学生物医学工程系获得学士和硕士学位,美国佛罗里达大学机械工程系获得博士学位。2008年-2009年,美国基因组公司任高级工程师;2009-2013年,美国亚利桑那州立大学生物设计研究院任博士后和助理研究员;2013年-2017年,美国Nanostring科技公司任高级研究员,具备工业界医疗仪器和试剂产品开发的完整经验。
主要从事微流控技术发展和相关仪器开发及其在生化检测和临床转化医学中的应用研究,对塑料材料制备微流控芯片进行了大量研究,在微流控芯片设计、材料选择、制造工艺、批量生产和质控等方面都积累了丰富的经验,在体外蛋白质合成微流控芯片、单分子基因扫描测序的微流控系统、DNA 纳米结构的分离微流控芯片、多重核酸和蛋白质定量检测等研究方向也取得了一些创新型成果。
Patent
Fluorescent Nucleic Acid Probe Detection Cartridge Assembly Unit. USD787700 S1
微生物燃料电池阳极的免疫修饰处理方法. 专利号 201110227982.4
一种肿瘤细胞的培养检验装置, 专利号 ZL01110250735.6
研究领域
一体化微流控芯片;微流控系统在快速分析、临床诊断、基因组和蛋白质组的应用;功能化DNA纳米自组装。
近期论文
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Publication
Q.Mei,R.H.Johnson,X.Wei,F.Su,Y.Liu,L.Kelbauskas,S.Lindsay,D.R.Meldrum,H.Yan."On-chip isotachophoresis separation of functional DNA origami capture nanoarrays from cell lysate",Nano Research,2013,6,712–719
H.Lu,F.Su,Q.Mei,Y.Tian,W.Tian,R.H.Johnson,D.R.Meldrum."Using fluorinecontaining amphiphilic random copolymers to manipulate the quantum yields of aggregation induced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging",Journal of Materials Chemistry,2012,22(19),9890-9900
H.Lu,F.Su,Q.Mei,X.Zhou,Y.Tian,W.Tian,R.H.Johnson,D.R.Meldrum.“A Series of poly[N-(2-hydroxypropyl)methacrylamide]copolymers with anthracene-derived fluorophores showing aggregation-Induced emission properties for bioimaging”,Journal of Polymer Science Part A,2012,50(5):890-899
F.Su,R.Alam,Q.Mei,Y.Tian,C.Youngbull,R.H.Johnson,D.R.Meldrum."Nanostructured oxygen sensor using micelles to incorporate a hydrophobic platinum porphyrin",PLoS One,2012,7(3):e33390
Q.Mei,X.Wei,F.Su,Y.Liu,C.Youngbull,R.H.Johnson,S.Lindsay,H.Yan,D.R.Meldrum.“Stability of DNA origami nanoarrays in cell lysate",Nano Letter,2011,11,1477–1482
F.Su,R.Alam,Q.Mei,Y.Tian,D.R.Meldrum,"Micelles as delivery vehicles for oligofluorene for bioimaging",PLoS One,2011,6(9):e24425
Q.Mei,R.Khnouf,A.Simon,H.Z.Fan.“Protein synthesis in a device with nanoporous membranes and microchannels”,Lab on a chip,2010,10,2541-2545
Q.Mei,Z.Xia,F.Xu,S.Soper,H.Z.Fan.“Fabrication of microfluidic reactors and mixing studies for luciferase detection.”Analytical Chemistry,2008,15,6045–6050
Q.Mei,C.K.Fredrickson,A.Simon,R.Khnouf,H.Z.Fan.“Cell-free protein synthesis in microfluidic array device”,Biotechnology Progress,2007,23,1305-1311
Q.Mei,C.K.Fredrickson,W.Lian,S.Jin,H.Z.Fan.“Ricin detection by a biological signal amplification in a well-in-well device”,Analytical Chemistry,2006,78,7659-7664
Q.Mei,C.K.Fredrickson,S.Jin,H.Z.Fan.“Toxin detection by a miniaturized in vitro protein expression array”,Analytical Chemistry,2005,77,5494-5500